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Volumn 26, Issue 6, 2012, Pages 325-329

The interaction among insulin resistance, liver fibrosis and early virological response in Egyptian patients with chronic hepatitis C

Author keywords

HCV; HCV therapy response; HOMA IR; Insulin resistance; Liver fibrosis

Indexed keywords

INSULIN; PEGINTERFERON ALPHA; PEGINTERFERON ALPHA2A; PEGYLATED INTERFERON ALPHA 2A; RIBAVIRIN; UNCLASSIFIED DRUG;

EID: 84862616045     PISSN: 08357900     EISSN: None     Source Type: Journal    
DOI: 10.1155/2012/291457     Document Type: Article
Times cited : (12)

References (37)
  • 1
    • 0037979127 scopus 로고    scopus 로고
    • Chronic hepatitis C virus infection
    • Flamm SL. Chronic hepatitis C virus infection. JAMA 2003;289:2413-7.
    • (2003) JAMA , vol.289 , pp. 2413-2417
    • Flamm, S.L.1
  • 2
    • 0034031216 scopus 로고    scopus 로고
    • Hepatitis C virus risk: A hepatitis C virus-related syndrome
    • Mazzaro C, Panarello G, Tesio F, et al. Hepatitis C virus risk: A hepatitis C virus-related syndrome. J Intern Med 2000;247:535-45.
    • (2000) J Intern Med , vol.247 , pp. 535-545
    • Mazzaro, C.1    Panarello, G.2    Tesio, F.3
  • 3
    • 0345655291 scopus 로고    scopus 로고
    • Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression
    • Hui JM, Sud A, Farrell GC, et al. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression. Gastroenterology 2003;125:1695-704.
    • (2003) Gastroenterology , vol.125 , pp. 1695-1704
    • Hui, J.M.1    Sud, A.2    Farrell, G.C.3
  • 4
    • 34548127047 scopus 로고    scopus 로고
    • Post-load insulin resistance is an independent predictor of hepatic fibrosis in virus C chronic hepatitis and in nonalcoholic fatty liver disease
    • Svegliati-Baroni G, Bugianesi E, et al. Post-load insulin resistance is an independent predictor of hepatic fibrosis in virus C chronic hepatitis and in nonalcoholic fatty liver disease. Gut 2007;56:1296-301.
    • (2007) Gut , vol.56 , pp. 1296-1301
    • Svegliati-Baroni, G.1    Bugianesi, E.2
  • 5
    • 44649166337 scopus 로고    scopus 로고
    • Associations between hepatitis C viremia and low serum triglyceride and cholesterol levels: A community-based study
    • Dai CY, Chuang WL, Ho CK, et al. Associations between hepatitis C viremia and low serum triglyceride and cholesterol levels: A community-based study. J Hepatol 2008;49:9-16.
    • (2008) J Hepatol , vol.49 , pp. 9-16
    • Dai, C.Y.1    Chuang, W.L.2    Ho, C.K.3
  • 6
    • 33845389796 scopus 로고    scopus 로고
    • Association between liver fibrosis and insulin sensitivity in chronic hepatitis C patients
    • Taura N, Ichikawa T, Hamasaki K, et al. Association between liver fibrosis and insulin sensitivity in chronic hepatitis C patients. Am J Gastroenterol 2006;101:2752-9.
    • (2006) Am J Gastroenterol , vol.101 , pp. 2752-2759
    • Taura, N.1    Ichikawa, T.2    Hamasaki, K.3
  • 7
    • 0034862555 scopus 로고    scopus 로고
    • Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C
    • Petit JM, Bour JB, Galland-Jos C, et al. Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C. J Hepatol 2001;35:279-83.
    • (2001) J Hepatol , vol.35 , pp. 279-283
    • Petit, J.M.1    Bour, J.B.2    Galland-Jos, C.3
  • 8
    • 1542287381 scopus 로고    scopus 로고
    • Hepatitis C virus infection and diabetes: Direct involvement of the virus in the development of insulin resistance
    • Shintani Y, Fujie H, Miyoshi H, et al. Hepatitis C virus infection and diabetes: Direct involvement of the virus in the development of insulin resistance. Gastroenterology 2004;126:840-8.
    • (2004) Gastroenterology , vol.126 , pp. 840-848
    • Shintani, Y.1    Fujie, H.2    Miyoshi, H.3
  • 9
    • 20144388828 scopus 로고    scopus 로고
    • Hepatitis C virus infection and human pancreatic b-cell dysfunction
    • Masini M, Campani D, Boggi U, et al. Hepatitis C virus infection and human pancreatic b-cell dysfunction. Diabetes Care 2005;28:940-1.
    • (2005) Diabetes Care , vol.28 , pp. 940-941
    • Masini, M.1    Campani, D.2    Boggi, U.3
  • 10
    • 7244243810 scopus 로고    scopus 로고
    • Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through upregulation of suppressor of cytokine signaling 3
    • Kawaguchi T, Yoshida T, Harada M, et al. Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through upregulation of suppressor of cytokine signaling 3. Am J Pathol 2004;165:1499-508.
    • (2004) Am J Pathol , vol.165 , pp. 1499-1508
    • Kawaguchi, T.1    Yoshida, T.2    Harada, M.3
  • 11
    • 0037059330 scopus 로고    scopus 로고
    • Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
    • Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MF. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem 2002;277:1531-7.
    • (2002) J Biol Chem , vol.277 , pp. 1531-1537
    • Aguirre, V.1    Werner, E.D.2    Giraud, J.3    Lee, Y.H.4    Shoelson, S.E.5    White, M.F.6
  • 12
    • 1842479859 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C
    • American Association for the Study of Liver Diseases
    • Strader DB, Wright T, Thomas DL, Seeff LB. American Association for the Study of Liver Diseases. Diagnosis, management, and treatment of hepatitis C. Hepatology 2004;39:1147-71.
    • (2004) Hepatology , vol.39 , pp. 1147-1171
    • Strader, D.B.1    Wright, T.2    Thomas, D.L.3    Seeff, L.B.4
  • 13
    • 15744381704 scopus 로고    scopus 로고
    • Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
    • Romero-Gomez M, Del MV, Andrade RJ, et al. Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients. Gastroenterology 2005;128:636-41
    • (2005) Gastroenterology , vol.128 , pp. 636-641
    • Romero-Gomez, M.1    Del, M.V.2    Andrade, R.J.3
  • 14
    • 71549129264 scopus 로고    scopus 로고
    • Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin
    • Grasso A, Malfatti F, De Leo P, et al. Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin. J Hepatol 2009;51:984-90.
    • (2009) J Hepatol , vol.51 , pp. 984-990
    • Grasso, A.1    Malfatti, F.2    De Leo, P.3
  • 15
    • 3442889936 scopus 로고    scopus 로고
    • Insulin resistance and insulin secretion in chronic hepatitis C virus infection
    • Narita R, Abe S, Kihara Y, Akiyama T, Tabarau A, Otsuki M. Insulin resistance and insulin secretion in chronic hepatitis C virus infection. J Hepatol 2004;41:132-8.
    • (2004) J Hepatol , vol.41 , pp. 132-138
    • Narita, R.1    Abe, S.2    Kihara, Y.3    Akiyama, T.4    Tabarau, A.5    Otsuki, M.6
  • 16
    • 0347994977 scopus 로고    scopus 로고
    • Tumor necrosis factor-a-induced insulin resistance may mediate the hepatitis C virus-diabetes association
    • Knobler H, Zhornicky T, Sandler A, Haran N, Ashur Y, Schattner A. Tumor necrosis factor-a-induced insulin resistance may mediate the hepatitis C virus-diabetes association. Am J Gastroenterol 2003;98:2751-6.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2751-2756
    • Knobler, H.1    Zhornicky, T.2    Sandler, A.3    Haran, N.4    Ashur, Y.5    Schattner, A.6
  • 17
    • 33846463006 scopus 로고    scopus 로고
    • Race, insulin resistance and hepatic steatosis in chronic hepatitis C
    • Conjeevaram HS, Kleiner DE, Everhart JE, et al. Race, insulin resistance and hepatic steatosis in chronic hepatitis C. Hepatology 2007;45:80-7.
    • (2007) Hepatology , vol.45 , pp. 80-87
    • Conjeevaram, H.S.1    Kleiner, D.E.2    Everhart, J.E.3
  • 18
    • 79958698124 scopus 로고    scopus 로고
    • A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt
    • Sievert W, Altraif I, Razavi HA, et al. A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt. Liver Int 2011;31(Suppl 2):61-80.
    • (2011) Liver Int , vol.31 , Issue.SUPPL. 2 , pp. 61-80
    • Sievert, W.1    Altraif, I.2    Razavi, H.A.3
  • 19
    • 1542378867 scopus 로고    scopus 로고
    • Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
    • Hadziyannis SJ, Sette Jr H, Morgan TR, et al. Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004;140:346-55.
    • (2004) Ann Intern Med , vol.140 , pp. 346-355
    • Hadziyannis, S.J.1    Sette Jr., H.2    Morgan, T.R.3
  • 20
    • 0028491096 scopus 로고
    • Chronic hepatitis: Morphology and nomenclature
    • Ishak KG. Chronic hepatitis: Morphology and nomenclature. Mod Pathol 1994;7:690-713.
    • (1994) Mod Pathol , vol.7 , pp. 690-713
    • Ishak, K.G.1
  • 21
    • 0033025254 scopus 로고    scopus 로고
    • Association of diabetes mellitus and chronic hepatitis C virus infection
    • Mason AL, Lau JY, Hoang N, et al. Association of diabetes mellitus and chronic hepatitis C virus infection. Hepatology 1999;29:328-33.
    • (1999) Hepatology , vol.29 , pp. 328-333
    • Mason, A.L.1    Lau, J.Y.2    Hoang, N.3
  • 22
    • 38449111521 scopus 로고    scopus 로고
    • Significance of glucose intolerance and SHIP2 expression in hepatocellular carcinoma patients with HCV infection
    • Sumie S, Kawaguchi T, Komuta M, et al. Significance of glucose intolerance and SHIP2 expression in hepatocellular carcinoma patients with HCV infection. Oncol Rep 2007;18:545-52.
    • (2007) Oncol Rep , vol.18 , pp. 545-552
    • Sumie, S.1    Kawaguchi, T.2    Komuta, M.3
  • 23
    • 0842321807 scopus 로고    scopus 로고
    • Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    • El-Serag HB, Tran T, Everhart JE. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 2004;126:460-8.
    • (2004) Gastroenterology , vol.126 , pp. 460-468
    • El-Serag, H.B.1    Tran, T.2    Everhart, J.E.3
  • 24
    • 21044456174 scopus 로고    scopus 로고
    • Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C
    • Fartoux L, Poujol-Robert A, Guéchot J, Wendum D, Poupon R, Serfaty L. Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C. Gut 2005;54:1003-8.
    • (2005) Gut , vol.54 , pp. 1003-1008
    • Fartoux, L.1    Poujol-Robert, A.2    Guéchot, J.3    Wendum, D.4    Poupon, R.5    Serfaty, L.6
  • 25
    • 51349122296 scopus 로고    scopus 로고
    • Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C
    • Cua IH, Hui JM, Kench JG, George J. Genotype-specific interactions of insulin resistance, steatosis, and fibrosis in chronic hepatitis C. Hepatology 2008;48:723-31
    • (2008) Hepatology , vol.48 , pp. 723-731
    • Cua, I.H.1    Hui, J.M.2    Kench, J.G.3    George, J.4
  • 26
    • 67449085321 scopus 로고    scopus 로고
    • Influence of insulin resistance on hepatic fibrosis and steatosis in hepatitis C virus (HCV) mono-infected compared with HIV-HCV co-infected patients
    • Epub March 9, 2009
    • Halfon P, Pénaranda G, Carrat F. Influence of insulin resistance on hepatic fibrosis and steatosis in hepatitis C virus (HCV) mono-infected compared with HIV-HCV co-infected patients. Aliment Pharmacol Ther 2009;30:61-70. Epub March 9, 2009.
    • (2009) Aliment Pharmacol Ther , vol.30 , pp. 61-70
    • Halfon, P.1    Pénaranda, G.2    Carrat, F.3
  • 27
    • 0034802171 scopus 로고    scopus 로고
    • High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
    • Paradis V, Perlemuter G, Bonvoust F, et al. High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis. Hepatology 2001;34:738-44.
    • (2001) Hepatology , vol.34 , pp. 738-744
    • Paradis, V.1    Perlemuter, G.2    Bonvoust, F.3
  • 28
    • 36549032819 scopus 로고    scopus 로고
    • Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3
    • Epub October 1, 2007
    • Poustchi H, Negro F, Hui J, et al. Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3. J Hepatol 2008;48:28-34. Epub October 1, 2007.
    • (2008) J Hepatol , vol.48 , pp. 28-34
    • Poustchi, H.1    Negro, F.2    Hui, J.3
  • 29
    • 21044450147 scopus 로고    scopus 로고
    • Steatosis, oxidative stress and fibrosis in chronic hepatitis C
    • Fartoux L, Serfaty L, Lefevre G, et al. Steatosis, oxidative stress and fibrosis in chronic hepatitis C. Hepatology 2003;38:363A.
    • (2003) Hepatology , vol.38
    • Fartoux, L.1    Serfaty, L.2    Lefevre, G.3
  • 30
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • Day CP, James OF. Steatohepatitis: A tale of two "hits"? Gastroenterology 1998;114:842-5.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 31
    • 0036158719 scopus 로고    scopus 로고
    • Steatosis and liver cancer in transgenic mice expressing the structural and non-structural proteins of hepatitis C virus
    • Lerat H, Honda M, Beard MR, et al. Steatosis and liver cancer in transgenic mice expressing the structural and non-structural proteins of hepatitis C virus. Gastroenterology 2002;122:352-65.
    • (2002) Gastroenterology , vol.122 , pp. 352-365
    • Lerat, H.1    Honda, M.2    Beard, M.R.3
  • 32
    • 0342716457 scopus 로고    scopus 로고
    • Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice
    • Letteron P, Fromenty B, Terris B, et al. Acute and chronic hepatic steatosis lead to in vivo lipid peroxidation in mice. J Hepatol 1996;24:200-8.
    • (1996) J Hepatol , vol.24 , pp. 200-208
    • Letteron, P.1    Fromenty, B.2    Terris, B.3
  • 33
    • 4143054671 scopus 로고    scopus 로고
    • Prevalence of non-significant liver fibrosis and rate of fibrosis progression in HIV/hepatitis C virus- co-infected patients: Still a role for liver biopsy?
    • Merchante N, Macías J, Palacios RB, et al. Prevalence of non-significant liver fibrosis and rate of fibrosis progression in HIV/hepatitis C virus- co-infected patients: Still a role for liver biopsy? AIDS 2004;18:1746-8.
    • (2004) AIDS , vol.18 , pp. 1746-1748
    • Merchante, N.1    Macías, J.2    Palacios, R.B.3
  • 34
    • 14844315985 scopus 로고    scopus 로고
    • Predictive value of early virological response to treatment with different interferon-based regimens plus ribavirin in patients with chronic hepatitis C
    • Napoli N, Giannelli G, Parisi CV, Antonaci A, Maddalena G, Antonaci S. Predictive value of early virological response to treatment with different interferon-based regimens plus ribavirin in patients with chronic hepatitis C. New Microbiol 2005;28:13-21.
    • (2005) New Microbiol , vol.28 , pp. 13-21
    • Napoli, N.1    Giannelli, G.2    Parisi, C.V.3    Antonaci, A.4    Maddalena, G.5    Antonaci, S.6
  • 35
    • 34250320980 scopus 로고    scopus 로고
    • Predictive value of rapid virological response and early virological response on sustained virological response in HCV patients treated with pegylated interferon alpha-2a and ribavirin
    • Yu JW, Wang GQ, Sun LJ, Li XG, Li SC. Predictive value of rapid virological response and early virological response on sustained virological response in HCV patients treated with pegylated interferon alpha-2a and ribavirin. J Gastroenterol Hepatol 2007;22:832-6.
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 832-836
    • Yu, J.W.1    Wang, G.Q.2    Sun, L.J.3    Li, X.G.4    Li, S.C.5
  • 36
    • 71549129264 scopus 로고    scopus 로고
    • Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin
    • Epub July 23, 2009
    • Grasso A, Malfatti F, De Leo P, et al. Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin. J Hepatol 2009;51:984-90. Epub July 23, 2009.
    • (2009) J Hepatol , vol.51 , pp. 984-990
    • Grasso, A.1    Malfatti, F.2    De Leo, P.3
  • 37
    • 77950602195 scopus 로고    scopus 로고
    • Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance
    • Epub November 16, 2009
    • Khattab M, Emad M, Abdelaleem A. Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance. Liver Int 2010;30:447-54. Epub November 16, 2009.
    • (2010) Liver Int , vol.30 , pp. 447-454
    • Khattab, M.1    Emad, M.2    Abdelaleem, A.3


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