Quality of life and adverse events after radiotherapy in gynecologic cancer survivors: A cohort study

Archives of Gynecology and Obstetrics

Volumn 284, Issue 6, 2011, Pages 1523-1531

  Vaz, Ana Francisca ^a   Conde, Délio Marques ^a,b   Costa Paiva, Lúcia ^a   Morais, Sirlei Siani ^a   Esteves, Sérgio Barros ^a   Pinto Neto, Aarão Mendes ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b Hospital Materno Infantil   (Brazil)

Author keywords

Adverse events; Gynecologic cancer; Quality of life; Radiotherapy

Indexed keywords

ADULT; AGED; ARTICLE; BLADDER BLEEDING; BRACHYTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVOR; COHORT ANALYSIS; COMMON TERMINOLOGY CRITERIA ADVERSE EVENT SCALE; CONTROLLED STUDY; DIARRHEA; DYSPAREUNIA; DYSURIA; ENVIRONMENTAL FACTOR; FEMALE; FUNCTIONAL STATUS; GYNECOLOGIC CANCER; HOT FLUSH; HUMAN; MAJOR CLINICAL STUDY; PAIN; PROSPECTIVE STUDY; PSYCHOLOGICAL ASPECT; QUALITY OF LIFE; RADIATION DOSE; RADIATION INJURY; RATING SCALE; RECTUM HEMORRHAGE; SEXUAL DYSFUNCTION; SOCIAL INTERACTION; URINE INCONTINENCE; VAGINA BLEEDING; VAGINAL DRYNESS; FEMALE GENITAL TRACT TUMOR; FOLLOW UP; LONGITUDINAL STUDY; MIDDLE AGED; QUESTIONNAIRE; RADIOTHERAPY; SURVIVOR;

ADULT; AGED; COHORT STUDIES; DYSPAREUNIA; FEMALE; FOLLOW-UP STUDIES; GENITAL NEOPLASMS, FEMALE; HUMANS; LONGITUDINAL STUDIES; MIDDLE AGED; PAIN; PROSPECTIVE STUDIES; QUALITY OF LIFE; QUESTIONNAIRES; RADIOTHERAPY; SURVIVORS; YOUNG ADULT;

EID: 84862608098     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-011-1886-x     Document Type: Article

References (43)

1. Leake RB, Gurrin LC, Hammond IG (2001) Quality of life in patients attending a low risk gynaecological oncology follow-up clinic. Psycho-Oncology 10:428-435 (Pubitemid 32904007)
2. Green JA, Kirwan JM, Tierney JF et al (2001) Survival and recurrence after concomitant chemotherapy and radiotherapy for cancer of the uterine cervix: a systematic review and metaanalysis. Lancet 358:140-147
3. Ryu HS, Chun M, Chang KH, Chang HJ, Lee JP (2005) Postoperative adjuvant concurrent chemotherapy improves survival rates for high-risk, early-stage cervical cancer patients. Gynecol Oncol 96:490-495 (Pubitemid 40127153)
4. Creutzberg C, Putten WLJV, Koper PC et al (2001) The morbidity of treatment for patients with stage I endometrial cancer: results from a randomized trial. Int J Radiat Oncol Biol Phys 51(5):246-255
5. Maher EJ, Delton A (2008) Survivorship, late effects and cancer of the cervix. Clin Oncol 20:479-487
6. Kirwan JM, Symonds P, Green JA, Tierney J, Collingwood M, Williams CJ (2003) A systematic review of acute and late toxicity of concomitant chemoradiation for cervical cancer. Radiother Oncol 68:217-226 (Pubitemid 38373421)
7. Agarwal S, Bodurka DC (2010) Symptom research in gynecology: a review of available measurements tools. Gynecol Oncol 119:384-389
8. Pedersen D, Bentzen SM, Overgaard J (1994) Early and late radiotherapeutic morbidity in 442 consecutive patients with locally advanced carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 29(5):941-952 (Pubitemid 24278959)
9. Vistad I, Cvancarova M, Fossa SD, Kristensen GB (2008) Post radiotherapy morbidity in long-term survivors after locally advanced cervical cancer: how well do physicians' assessment agree with those of their patients. Int J Radiat Oncol Biol Phys 71(5):1335-1342
10. Li C, Samsioe G, Iosif C (1999) Quality of life in endometrial cancer survivors. Maturitas 31:227-236 (Pubitemid 29132824)
11. Jensen PT, Groenvold M, Klee MC, Tharanov I, Petersen MA, Machin D (2003) Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 56:937-949 (Pubitemid 36794024)
12. Bye A, Tropé C, Loge JH, Hjermstad M, Kaasa S (2000) Healthrelated quality of life and occurrence of intestinal side-effects after pelvic radiotherapy; evaluation of long-term effects of diagnosis and treatment. Acta Oncol 39:173-180 (Pubitemid 30316884)
13. Flay LD, Matthews HL (1995) The effects of radiotherapy and surgery on the sexual function of women treated for cervical cancer. Int J Radiat Oncol Biol Phys 31(2):399-404
14. Frumovitz M, Sun CC, Schover LR et al (2005) Quality of life and sexual functioning in cervical cancer survivors. J Clin Oncol 23(30):7428-7436 (Pubitemid 46291804)
15. Lalos O, Kjellberg L, Lalos A (2009) Urinary, climacteric and sexual symptoms 1 year after treatment of cervical cancer without brachytherapy. J Psychosom Obstet Gynecol 30(4):269-274
16. Park YS, Bae D-S, Nam JH et al (2007) Quality of life and sexual problems in disease-free survivors of cervical cancer compared with the general population. Cancer 110:2716-2725 (Pubitemid 350250341)
17. Wan GJ, Counte MA, Cella DF (1997) The influence of personal expectations on cancer patients' reports of health-related quality of life. Psychooncology 6:1-11 (Pubitemid 27195758)
18. Vaz AF, Pinto-Neto AM, Conde DM, Costa-Paiva L, Morais SS, Esteves SB (2007) Quality of life of women with gynecologic cancer: associated factors. Arch Gynecol Obstet 276:583-589 (Pubitemid 350029502)
19. Bradley S, Stephen R, Lutgendorf S, Costanzo E, Anderson B (2006) Quality of life and mental health in cervical and endometrial cancer survivors. Gynecol Oncol 100:479-486 (Pubitemid 43246862)
20. Bye A, Ose T, Kaasa S (1995) Quality of life during pelvic radiotherapy. Acta Obstet Gynecol Scand 74:147-152
21. Chan YM, Ngan HY, Li BY et al (2001) A longitudinal study on quality of life after gynecologic cancer treatment. Gynecol Oncol 83:10-19 (Pubitemid 32959873)
22. Greimel E, Thiel I, Peintinger F, Cegnar I, Pongratz E (2002) Prospective assessment of quality of life of female cancer patients. Gynecol Oncol 85:140-147 (Pubitemid 34304024)
23. Barker CL, Routledge JA, Farnell DJJ, Swindell R, Davidson SE (2009) The impact of radiotherapy late effects on quality of life in gynaecological cancer patients. Br J Cancer 100:1558-1565
24. Denton AS, Bond SJ, Matthws S, Bentzen SM, Maher EJ, UK Link Gynaecologic-Oncology Group (2000) National audit of the management and outcome of carcinoma of the cervix treated with radiotherapy in 1993. Clinic Oncol 69:195-200
25. Vaz AF, Pinto-Neto AM, Conde DM, Costa-Paiva L, Morais SS, Esteves SB (2008) Quality of life and acute toxicity of radiotherapy in women with gynecologic cancer: a prospective longitudinal study. Arch Gynecol Obstet 278(3):215-223
26. Common Terminology Criteria Adverse Event scale (CTCAE) v 3.0. Available at http://ctep. cancer.gov/protocolDeveloment/electronic-applications/docs/ ctcaev3.pdf. Accessed 1 March 2005
27. WHOQOL Group (1998) Development of the World Health Organization WHOQOL-BREF quality of life assessment. Psychol Med 28:551-558
28. Fleck MP, Louzada S, Xavier M et al (2000) Application of the Portuguese version of the abbreviated instrument of quality of life WHOQOL-bref. Rev Saude Publica 34:178-183
29. Hoyle RH ed (1995) Structural equation modeling: concepts, issues and applications. Sage Publications Inc, Thousand Oaks CA
30. SAS Institute Inc. SAS/STAT software changes and enhancements though release 8.2 Cary, NC: SAS Institute, Inc. 1999-2001
31. Hsu WC, Chung NN, Chen YC et al (2009) Comparison of surgery or radiotherapy on complications and quality of life in patients with stage IB and IIA uterine cervical cancer. Gynecol Oncol 115(1):41-45
32. Klee M, Thranov I, Marchin D (2000) The patients' perspective on physical symptoms after radiotherapy for cervical cancer. Gynecol Oncol 76:14-23 (Pubitemid 30048313)
33. Mundt AJ, Mell LK, Roeske JC (2003) Preliminary analysis of chronic gastrointestinal toxicity in gynecology patients treated with intensity-modulated whole pelvic radiation therapy. Int J Radiat Oncol Biol Phys 56(5):1354-1360 (Pubitemid 36842887)
34. Wenzel L, DeAlba I, Habbal R et al (2005) Quality of life in long-term cervical cancer survivors. Gynecol Oncol 97:310-317 (Pubitemid 40614869)
35. Korfage IJ, Essink-Bot ML, Mols F, van de Poll-Franse L, Kruitwagen R, van Ballegooijen M (2009) Health-related quality of life in cervical cancer survivors: a population-based survey. Int J Radiat Oncol Biol Phys 73(5):1501-1509
36. Thranov I, Klee M (1994) Sexuality among gynecologic cancer patients-a cross-sectional study. Gynecol Oncol 52:14-19
37. Bergmark K, Avall-Lundqvist E, Dickman PW, Henningsohn L, Steineck G (1999) Vaginal changes and sexuality in women with a history of cervical cancer. N Engl J Med 340:1383-1389 (Pubitemid 29205401)
38. Lutgendorf SK, Anderson B, Ullrich P et al (2002) Quality of life and mood in women with gynecologic cancer: a one year prospective study. Cancer 94:131-140 (Pubitemid 34049051)
39. Greimel ER, Winter R, Kapp KS, Haas J (2009) Quality of life and sexual functioning after cervical cancer treatment: a longterm follow-up study. Psycho-Oncology 18:476-482
40. Abayomi J, Kirwan J, Hackett A (2009) The prevalence of chronic radiation enteritis following radiotherapy for cervical or endometrial cancer and its impact on quality of life. Eur J Oncol Nurs 13:262-267
41. Rummans TA, Frost M, Suman VJ et al (1998) Quality of life and pain in patients with recurrent breast and gynecologic cancer. Psychosomatics 39:437-445 (Pubitemid 28439944)
42. Vaz AF, Pinto-Neto AM, Conde DM, Costa-Paiva L, Morais SS, Pedro AO, Esteves SB (2010) Quality of life, menopause and sexual symptoms in gynecologic cancer survivors: a cohort study. Accepted for publication in Menopause 18(6): june 2011 issue
43. Avis NE, Smith KW, McGraw S, Smith RG, Petronis VM, Carver CS (2005) Assessing quality of life in adult cancer survivors (QLACS). Qual Life Res 14:1007-1023 (Pubitemid 40685224)