Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues

Annals of the Rheumatic Diseases

Volumn 71, Issue 7, 2012, Pages 1254-1258

  Bos, Steffan Daniël ^a,b   Boveáe, Judith V M G ^a   Duijnisveld, Bouke J ^a   Raine, Emma V A ^c   Dalen, Wouter Jvan ^a   Ramos, Yolande F M ^a   Van Der Breggen, Ruud ^a   Nelissen, Rob G H H ^a   Slagboom, P Eline ^a,b   Loughlin, John ^c   Meulenbelt, Ingrid ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Netherlands Consortium for Healthy Ageing   (Netherlands)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEIODINASE TYPE 2; IODIDE PEROXIDASE; MESSENGER RNA; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELIC IMBALANCE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIO2 GENE; ENZYME LOCALIZATION; FEMALE; GENE; GENE IDENTIFICATION; GENE LOCATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIGAMENT; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; RISK ASSESSMENT; TISSUE DISTRIBUTION; UPREGULATION; WILD TYPE;

ADULT; AGED; AGED, 80 AND OVER; CARTILAGE, ARTICULAR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; IODIDE PEROXIDASE; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 84862565364     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2011-200981     Document Type: Article

References (13)

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