Lyase activity of glycogen synthase: Is an elimination/addition mechanism a possible reaction pathway for retaining glycosyltransferases?

IUBMB Life

Volumn 64, Issue 7, 2012, Pages 649-658

  Díaz, Adelaida ^a,b   Díaz Lobo, Mireia ^a,b,c   Grados, Enrique ^c   Guinovart, Joan J ^a,b,c   Fita, Ignacio ^a,d   Ferrer, Joan C ^c  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSITY OF BARCELONA   (Spain)

^d INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

Author keywords

1,5 anhydro D fructose; catalytic mechanism; glycogen synthase; protein structure; retaining glycosyltransferase

Indexed keywords

CARBON; FRUCTOSE; GLUCOSE; GLYCOGEN SYNTHASE; GLYCOSYLTRANSFERASE; LYASE; OXYGEN; PHOSPHATE; URIDINE DIPHOSPHATE;

ADDITION REACTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; COVALENT BOND; CRYSTAL STRUCTURE; CRYSTALLIZATION; DENSITY; DERIVATIZATION; DONOR; ELIMINATION REACTION; ENZYME ACTIVITY; ESCHERICHIA COLI; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; NONHUMAN; PROTEIN EXPRESSION; PYROCOCCUS ABYSSI; TAUTOMER; X RAY DIFFRACTION;

BINDING SITES; BIOCHEMISTRY; CATALYSIS; CATIONS; CHROMATOGRAPHY, LIQUID; DNA, COMPLEMENTARY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLYCOGEN SYNTHASE; GLYCOSYLTRANSFERASES; LYASES; MODELS, CHEMICAL; MOLECULAR CONFORMATION; OXYGEN; PROTONS; URIDINE DIPHOSPHATE; X-RAY DIFFRACTION;

EID: 84862563880     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.1048     Document Type: Article

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