Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven by the Syntaxin N-peptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 25, 2012, Pages 9816-9821

  Christie, Michelle P ^a   Whitten, Andrew E ^a   King, Gordon J ^a   Hu, Shu Hong ^a   Jarrott, Russell J ^a   Chen, Kai En ^a   Duff, Anthony P ^b   Callow, Philip ^c   Collins, Brett M ^a   James, David E ^d   Martin, Jennifer L ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^c INSTITUT LAUE LANGEVIN   (France)

^d GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Membrane fusion; Protein interactions; Small angle neutron scattering; Small angle X ray scattering

Indexed keywords

MUNC18 PROTEIN; NEUROPEPTIDE; SNARE PROTEIN; SYNTAXIN; SYNTAXIN 1A; SYNTAXIN 4;

ADIPOCYTE; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; CRYSTAL STRUCTURE; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

MUNC18 PROTEINS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; SCATTERING, SMALL ANGLE; X-RAY DIFFRACTION;

EID: 84862561705     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1116975109     Document Type: Article

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