Sepsis-induced acute kidney injury-is there a lack of energy?

Intensive Care Medicine

Volumn 38, Issue 5, 2012, Pages 735-737

  Frithiof, Robert ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE TRIPHOSPHATE; ANGIOTENSIN II; CREATININE; ENDOTHELIN; INFUSION FLUID; ISOFLURANE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NORADRENALIN; TOLL LIKE RECEPTOR 4;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; ANURIA; APOPTOSIS; CARDIOVASCULAR FUNCTION; CREATININE CLEARANCE; CRITICALLY ILL PATIENT; DISEASE SEVERITY; EDITORIAL; ENERGY CONSUMPTION; ESCHERICHIA COLI; GLOMERULUS FILTRATION RATE; GRAM NEGATIVE BACTERIUM; HUMAN; HYPOTENSION; HYPOXIA; INFLAMMATORY DISEASE; INNATE IMMUNITY; INTENSIVE CARE UNIT; KIDNEY BLOOD FLOW; KIDNEY FAILURE; MORBIDITY; MORTALITY; NONHUMAN; OXYGEN CONSUMPTION; OXYGEN EXTRACTION FRACTION; OXYGEN SUPPLY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRESSORECEPTOR; SEPSIS; SEPTIC SHOCK; SHEEP; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; URINE VOLUME;

ANGIOTENSIN II; ANIMALS; ENERGY METABOLISM; GRAM-NEGATIVE AEROBIC BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; KIDNEY; SEPSIS; VASOCONSTRICTOR AGENTS;

EID: 84862544455     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2489-0     Document Type: Editorial

References (16)

1. Singbartl K, Kellum JA (2011) AKI in the ICU: definition, epidemiology, risk stratification, and outcomes. Kidney Int. doi:10.1038/ki.2011.339
2. Lafrance JP, Miller DR (2010) Acute kidney injury associates with increased long-term mortality. J Am Soc Nephrol 21:345-352
3. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C, Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294:813-818
4. Ali T, Khan I, Simpson W, Prescott G, Townend J, Smith W, Macleod A (2007) Incidence and outcomes in acute kidney injury: a comprehensive population-based study. J Am Soc Nephrol 18:1292-1298
5. Bagshaw SM, Lapinsky S, Dial S, Arabi Y, Dodek P, Wood G, Ellis P, Guzman J, Marshall J, Parrillo JE, Skrobik Y, Kumar A, Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group (2009) Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy. Intensive Care Med 35:871-881
6. Legrand M, Bezemer R, Kandil A, Demirci C, Payen D, Ince C (2011) The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats. Intensive Care Med 37:1534-1542
7. Kikeri D, Pennell JP, Hwang KH, Jacob AI, Richman AV, Bourgoignie JJ (1986) Endotoxemic acute renal failure in awake rats. Am J Physiol 250:F1098-F1106
8. Yasuda H, Yuen PS, Hu X, Zhou H, Star RA (2006) Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects. Kidney Int 69:1535-1542
9. Brenner M, Schaer GL, Mallory DL, Suffredini AF, Parrillo JE (1990) Detection of renal blood flow abnormalities in septic and critically ill patients using a newly designed indwelling thermodilution renal vein catheter. Chest 98:170-179
10. Lerolle N, Nochy D, Guerot E, Bruneval P, Fagon JY, Diehl JL, Hill G (2010) Histopathology of septic shock induced acute kidney injury: apoptosis and leukocytic infiltration. Intensive Care Med 36:471-478
11. Fenhammar J, Rundgren M, Forestier J, Kalman S, Eriksson S, Frithiof R (2011) Toll-like receptor 4 inhibitor TAK-242 attenuates acute kidney injury in endotoxemic sheep. Anesthesiology 114:1130-1137
12. Langenberg C, Wan L, Egi M, May CN, Bellomo R (2006) Renal blood flow in experimental septic acute renal failure. Kidney Int 69:1996-2002
13. Andersson A, Rundgren M, Kalman S, Rooyackers O, Brattstrom O, Oldner A, Eriksson S, Frithiof R (2011) Gut microcirculatory and mitochondrial effects of hyperdynamic endotoxaemic shock and norepinephrine treatment. Br J Anaesth. doi:10.1093/bja/aer379
14. Wan L, Langenberg C, Bellomo R, May CN (2009) Angiotensin II in experimental hyperdynamic sepsis. Crit Care 13:R190
15. Frithiof R, Soehnlein O, Eriksson S, Fenhammar J, Hjelmqvist H, Lindbom L, Rundgren M (2011) The effects of isoflurane anesthesia and mechanical ventilation on renal function during endotoxemia. Acta Anaesthesiol Scand 55:401-410
16. Redfors B, Bragadottir G, Sellgren J, Sward K, Ricksten SE (2010) Acute renal failure is NOT an ''acute renal success''-a clinical study on the renal oxygen supply/demand relationship in acute kidney injury. Crit Care Med 38:1695-1701