Decreased affinity of mosaic-structure recombinant penicillin-binding protein 2 for oral cephalosporins in neisseria gonorrhoeae

Journal of Antimicrobial Chemotherapy

Volumn 60, Issue 1, 2007, Pages 54-60

  Ochiai, Susumu ^a,b   Sekiguchi, Satomi ^a   Hayashi, Akio ^a   Shimadzu, Mitsunobu ^a   Ishiko, Hiroaki ^a   Matsushima Nishiwaki, Rie ^b   Kozawa, Osamu ^b   Yasuda, Mitsuru ^b   Deguchi, Takashi ^b  

^a LSI MEDIENCE CORPORATION   (Japan)

^b GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cephem; Competition assay; Fluorescent penicillin; Mosaic; PBP 2

Indexed keywords

CEFDINIR; CEFIXIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; PENICILLIN BINDING PROTEIN; PENICILLIN G; RECOMBINANT PENICILLIN BINDING PROTEIN 2; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; GONORRHEA; HUMAN; INSECT CELL; MALE; MINIMUM INHIBITORY CONCENTRATION; NEISSERIA GONORRHOEAE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN STRUCTURE;

ADMINISTRATION, ORAL; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACULOVIRIDAE; CELLS, CULTURED; CEPHALOSPORINS; HUMANS; MALE; MOSAICISM; NEISSERIA GONORRHOEAE; PENICILLIN-BINDING PROTEINS; RECOMBINANT PROTEINS; SPODOPTERA;

EID: 34447563781     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkm166     Document Type: Article

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