Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats

Acta Pharmacologica Sinica

Volumn 33, Issue 6, 2012, Pages 775-782

  Wu, Wen Shiann ^a   Chou, Ming Ting ^a   Chao, Chien Ming ^b   Chang, Chen Kuei ^c   Lin, Mao Tsun ^b,c   Chang, Ching Ping ^d  

^a CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

acute lung injury; free radicals; heat stroke; interleukins; melatonin; nitric oxide; tumor necrosis factor alpha; Wistar rats

Indexed keywords

2,3 DIHYDROXYBENZOIC ACID; GLUTAMIC ACID; HYDROXYL RADICAL; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LACTIC ACID; MELATONIN; MYELOPEROXIDASE; NITRIC OXIDE; PYRUVIC ACID; SALICYLATE SODIUM; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEAT STRESS; HEAT STROKE; HYDROXYLATION; HYPERTHERMIA; HYPOTENSION; LUNG EDEMA; LUNG HEMORRHAGE; LUNG LAVAGE; MALE; MICRODIALYSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OUTCOME ASSESSMENT; PLEURA FLUID; PNEUMONIA; POLYMORPHONUCLEAR CELL; RAT; ROOM TEMPERATURE; SURVIVAL TIME; THERAPY EFFECT; UPREGULATION;

ACUTE LUNG INJURY; ANIMALS; ANTIOXIDANTS; BRONCHOALVEOLAR LAVAGE FLUID; FEVER; HEAT STROKE; HEMORRHAGE; HYPOTENSION; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; LUNG; MALE; MELATONIN; NITRIC OXIDE; PULMONARY EDEMA; RATS; RATS, WISTAR; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84862534483     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.29     Document Type: Article

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