B-type natriuretic peptide (BNP) affects the initial response to intravenous glucose: A randomised placebo-controlled cross-over study in healthy men

Diabetologia

Volumn 55, Issue 5, 2012, Pages 1400-1405

  Heinisch, B B ^a   Vila, G ^a   Resl, M ^a   Riedl, M ^a   Dieplinger, B ^b   Mueller, T ^b   Luger, A ^a   Pacini, G ^c   Clodi, M ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Hospital St John of God   (Austria)

^c CNR   (Italy)

Author keywords

BNP; C peptide; Diabetes; Glucose; Healthy volunteers; Heart failure; Insulin sensitivity; IVGTT

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; BRAIN NATRIURETIC PEPTIDE 32; C PEPTIDE; GLUCOSE; INSULIN; NEUTRAL INSULIN; PLACEBO; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; BLOOD PRESSURE; BODY MASS; CONTINUOUS INFUSION; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET RESTRICTION; DISTRIBUTION VOLUME; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HEART RATE; HUMAN; HUMAN EXPERIMENT; INSULIN CLEARANCE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; MALE; METABOLISM; NORMAL HUMAN; OPEN STUDY; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; RANDOMIZED CONTROLLED TRIAL; SIGNAL TRANSDUCTION; SINGLE BLIND PROCEDURE; TREATMENT RESPONSE; UNIVERSITY HOSPITAL;

ADULT; BLOOD GLUCOSE; C-PEPTIDE; CROSS-OVER STUDIES; GLUCOSE TOLERANCE TEST; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; NATRIURETIC AGENTS; NATRIURETIC PEPTIDE, BRAIN; YOUNG ADULT;

EID: 84862533076     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2392-1     Document Type: Article

References (30)

1. Nichols GA, Gullion CM, Koro CE, Ephross SA, Brown JB (2004) The incidence of congestive heart failure in type 2 diabetes: an update. Diabetes Care 27: 1879-1884
2. Egstrup M, Schou M, Gustafsson I, Kistorp CN, Hildebrandt PR, Tuxen CD (2011) Oral glucose tolerance testing in an outpatient heart failure clinic reveals a high proportion of undiagnosed diabetic patients with an adverse prognosis. Eur J Heart Fail 13: 319-326
3. Clodi M, Resl M, Stelzeneder D et al (2009) Interactions of glucose metabolism and chronic heart failure. Exp Clin Endocrinol Diabetes 117: 99-106
4. Andersson C, Norgaard ML, Hansen PR et al (2010) Heart failure severity, as determined by loop diuretic dosages, predicts the risk of developing diabetes after myocardial infarction: a nationwide cohort study. Eur J Heart Fail 12: 1333-1338
5. Shimabukuro M, Higa N, Asahi T et al (2011) Impaired glucose tolerance, but not impaired fasting glucose, underlies leftventricular diastolic dysfunction. Diabetes Care 34: 686-690
6. Massie B, Conway M, Yonge R et al (1987) Skeletal muscle metabolism in patients with congestive heart failure: relation to clinical severity and blood flow. Circulation 76: 1009-1019
7. Swan JW, Anker SD, Walton C et al (1997) Insulin resistance in chronic heart failure: relation to severity and etiology of heart failure. J Am Coll Cardiol 30: 527-532
8. Uriel N, Naka Y, Colombo PC et al (2011) Improved diabetic control in advanced heart failure patients treated with left ventricular assist devices. Eur J Heart Fail 13: 195-199
9. Ruskoaho H (2003) Cardiac hormones as diagnostic tools in heart failure. Endocr Rev 24: 341-356
10. Daniels LB, Maisel AS (2007) Natriuretic peptides. J Am Coll Cardiol 50: 2357-2368
11. Vila G, Resl M, Stelzeneder D et al (2008) Plasma NT-proBNP increases in response to LPS administration in healthy men. J Appl Physiol 105: 1741-1745
12. Maisel AS, Krishnaswamy P, Nowak RM et al (2002) Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med 347: 161-167
13. McKenna K, Smith D, Tormey W, Thompson CJ (2000) Acute hyperglycaemia causes elevation in plasma atrial natriuretic peptide concentrations in type 1 diabetes mellitus. Diabet Med 17: 512-517
14. Tanabe A, Naruse M, Wasada T et al (1995) Effects of acute hyperinsulinemia on plasma atrial and brain natriuretic peptide concentrations. Eur J Endocrinol 132: 693-698
15. Ang DS, Welsh P, Watt P, Nelson SM, Struthers A, Sattar N (2009) Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and prognosis. Clin Sci 117: 41-48
16. Yamaji M, Tsutamoto T, Tanaka Tet al (2009) Effect of carperitide on plasma adiponectin levels in acute decompensated heart failure in patients with diabetes mellitus. Circ J 12: 2264-2269
17. Stolley PD, Strom BL (1986) Sample size calculations for clinical pharmacology studies. Clin Pharmacol Ther 39: 489-490
18. Pacini G, Tonolo G, Sambataro M et al (1998) Insulin sensitivity and glucose effectiveness: minimal model analysis of regular and insulin-modified FSIGT. Am J Physiol 274: E592-E599
19. Bergman RN (1989) Toward physiological understanding of glucose tolerance. Minimal-model approach. Diabetes 38: 1512-1527
20. Tura A, Sbrignadello S, Succurro E, Groop L, Sesti G, Pacini G (2010) An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics. Diabetologia 53: 144-152. Erratum 53: 1245
21. Stadler M, Anderwald C, Karer T et al (2006) Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation. A sign of impaired beta cell function? Diabetes Care 29: 1031-1038
22. Gibaldi M, Perrier D (1982) Pharmacokinetics, 2nd edn. Marcel Dekker, New York.
23. Ahrén B, Pacini G (2004) Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies. Eur J Endocrinol 150: 97-104
24. van der Zander K, Houben AJ, Hofstra L, Kroon AA, de Leeuw PW (2008) Hemodynamic and renal effects of low-dose brain natriuretic peptide infusion in humans: a randomized, placebocontrolled crossover study. Am J Physiol Heart Circ Physiol 285: H1206-H1212
25. Prahash A, Lynch T (2004) B-type natriuretic peptide: a diagnostic, prognostic, and therapeutic tool in heart failure. Am J Crit Care 13: 46-53, quiz 54-55. Review. Erratum 13: 101
26. Han J, Mandal AK, Hiebert LM (2005) Endothelial cell injury by high glucose and heparanase is prevented by insulin, heparin and basic fibroblast growth factor. Cardiovasc Diabetol 4: 12
27. Wang TJ, Larson MG, Keyes MJ, Levy D, Benjamin EJ, Vasan RS (2007) Association of plasma natriuretic peptide levels with metabolic risk factors in ambulatory individuals. Circulation 115: 1345-1353
28. Miyashita K, Itoh H, Tsujimoto H et al (2009) Natriuretic peptides/cGMP/cGMP-dependent protein kinase cascades promote muscle mitochondrial biogenesis and prevent obesity. Diabetes 58: 2880-2892
29. Polak J, Kotrc M, Wedellova Z et al (2011) Lipolytic effects of B-type natriuretic peptide(1-32) in adipose tissue of heart failure patients compared with healthy controls. J Am Coll Cardiol 11: 1119-1125
30. Miller WL, Phelps MA, Wood CM et al (2011) Comparison of mass spectrometry and clinical assay measurements of circulating fragments of B-type natriuretic peptide in patients with chronic heart failure. Circ Heart Fail 4: 355-360