The use of rhDNAse in severely ill, non-intubated adult asthmatics refractory to bronchodilators: A pilot study

Respiratory Medicine

Volumn 106, Issue 8, 2012, Pages 1096-1102

  Silverman, Robert A ^a,b   Foley, Finbar ^a,c   Dalipi, Resul ^a,d,e   Kline, Myriam ^b   Lesser, Martin ^b  

^a LONG ISLAND JEWISH MEDICAL CENTER   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Milford Hospital ^*  (United States)

^e Milford Hospital   (United States)

Author keywords

Acute; Asthma; rhDNAse; Severe

Indexed keywords

DEOXYRIBONUCLEASE; IPRATROPIUM BROMIDE; PLACEBO; RECOMBINANT HUMAN DEOXYRIBONUCLEASE; SALBUTAMOL; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG SAFETY; DRUG USE; FOLLOW UP; FORCED EXPIRATORY VOLUME; HOSPITALIZATION; HUMAN; LUNG FIBROSIS; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; VISCOELASTICITY;

ADOLESCENT; ADULT; ASTHMA; BRONCHODILATOR AGENTS; DEOXYRIBONUCLEASE I; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; EXPECTORANTS; FEMALE; FORCED EXPIRATORY VOLUME; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PILOT PROJECTS; TREATMENT FAILURE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84862527401     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2012.04.002     Document Type: Article

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