An unusually low prevalence of huntington's disease in Iceland

European Neurology

Volumn 68, Issue 1, 2012, Pages 48-51

  Sveinsson, Ólafur ^a,d   Halldórsson, Sigurur ^b   Olafsson, Elias ^a,c  

^a LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^b Kopasker Health Care Center   (Iceland)

^c UNIVERSITY OF ICELAND   (Iceland)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Chorea; Dementia; Prevalence; Trinucleotide repeats

Indexed keywords

ADULT; AGED; ARTICLE; AUTOSOMAL DOMINANT DISORDER; FEMALE; HUMAN; HUNTINGTON CHOREA; ICELAND; INCIDENCE; INVOLUNTARY MOVEMENT; MALE; MENTAL DISEASE; NORWAY; PREVALENCE; PRIORITY JOURNAL; SYMPTOM;

ADULT; FEMALE; HISTORY, 16TH CENTURY; HUMANS; HUNTINGTON DISEASE; ICELAND; INCIDENCE; MALE; MIDDLE AGED; PREVALENCE; YOUNG ADULT;

EID: 84862506894     PISSN: 00143022     EISSN: 14219913     Source Type: Journal    
DOI: 10.1159/000337680     Document Type: Article

References (25)

1. Kremer B: Clinical neurology of Hunting-ton's disease; in Bates G, Harper P, Jones L (eds): Huntington's Disease. Oxford, Oxford University Press, 2002, pp 28-53.
2. Harper P: The epidemiology of Huntington's disease; in Bates G, Harper P, Jones L (eds): Huntington's Disease. Oxford, Oxford Uni-versity Press, 2002, pp 159-189.
3. Paolo J, Somer H, Ikonen EM, Karila L, Perl-tonen L: Low prevalence of Huntington's dis-ease in Finland. Lancet 1987; 2: 805-806. (Pubitemid 17133158)
4. Harper PS: The epidemiology of Hunting-ton's disease. Hum Genet 1992; 89:365-376.
5. Gudmundsson KR: Prevalence and occur-rence of some rare neurological diseases in Iceland. Acta Neurol Scand 1969; 45:114-118.
6. Helgason A, Sigurthardóttir S, Gulcher JR, Ward R, Stefánsson K: mtDNA and the ori-gin of the Icelanders: deciphering signals of recent population history. Am J Hum Genet 2000; 66:999-1016. (Pubitemid 30470501)
7. Saugstad L, Odegard O: Huntington's chorea in Norway Psychol Med 1986; 16:39-48. (Pubitemid 16130404)
8. Mattsson B: Huntington's chorea in Sweden. I. Prevalence and genetic data. Acta Psychi-atr Scand (Suppl) 1974; 255: 211-255.
9. Simpson A, Johnston AW: The prevalence and patterns of care of Huntington's chorea in Grampian. Br J Psychiatry 1989; 155: 799-804. (Pubitemid 20086775)
10. Sjögren T: Vererbungsmedizinische Unter-suchungen über Huntingtons Chorea in ein-er schwedischen Bauernpopulation. Vererb-konstit-Lehre 1936; 19: 131-165.
11. Avila-Giron R: Medical and social aspects of Huntington's chorea in the state of Zulia, Venezuela; in Barbeau A, Chase TN, Paulson GW (eds): Advances in Neurology. New York, Raven Press, 1973, vol 1, pp 261-266.
12. Brothers CRD: The history and incidence of Huntington's chorea in Tasmania. Proceed-ings of the Royal Australian College of Physi-cians 1949; 4: 48-50.
13. Pridmore SA: The prevalence of Hunting-ton's disease in Tasmania. Med J Aust 1990; 153: 133-134.
14. Lyon RL: Huntington's chorea in the Moray Firth area. Br Med J 1962; 1: 1301-1306.
15. Walker DA, Harper PS, Wells CEC, Tyler A, Davies K, Newcombe RG: Huntington's cho-rea in South Wales: a genetic and epidemio-logical study. Clin Genet 1981; 19: 213-221. (Pubitemid 11067772)
16. Bergsteinsson H, Baldursson Ó, Clausen M, Cook E, Ólafsson I: Cystic fibrosis in Iceland 1955-2005; incidence, survival and CFT mu-tations in the Icelandic population. J Cyst Fi-bros 2006; 5(suppl 1):S102.
17. Helgason A, Pálsson S, Gudbjartsson DF, Kristjánsson T, Stefánsson K: An association between the kinship and fertility of human couples. Science 2008; 319: 813-816. (Pubitemid 351225871)
18. Pridmore SA: Age of onset of Huntington's disease in Tasmania. Med J Aust 1990; 153: 135-137. (Pubitemid 20244924)
19. Haines JL, Conneally PM: Causes of death in Huntington's disease as reported on death cer-tificates. Genet Epidemiol 1986; 3: 417-423. (Pubitemid 17234610)
20. Lanska DJ, Lanska MJ, Lavine L, Schoenberg BS: Conditions associated with Huntington's disease at death. A case-control study. Arch Neurol 1988; 45:878-880.
21. Pridmore SA: Age of death and duration in Huntington's disease in Tasmania. Med J Australia 1990; 153: 137-139. (Pubitemid 20244925)
22. Huntington G: On chorea. Med Surg Report-er 1872; 26: 320-321.
23. Chandler JH, Reed TE, de Jong RN: Hun-tington's chorea in Michigan. III Clinical ob-servations. Neurology 1960; 10:148-153.
24. Sorensen SA, Fenger K: Causes of death in patients with Huntington's disease and in unaffected first degree relatives. J Med Gen-et 1992; 29:911-914. (Pubitemid 23035219)
25. Hendricks AE, Latourelle JC, Lunetta KL, Cupples LA, Wheeler V, MacDonald ME, Gusella JF, Myers RH: Estimating the prob-ability of de novo HD cases from transmis-sions of expanded penetrant CAG alleles in the Huntington disease gene from male car-riers of high normal alleles (27-35 CAG). Am J Med Genet A 2009; 149A:1375-1381.