Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model

Blood

Volumn 119, Issue 24, 2012, Pages 5871-5878

  Hilden, Ida ^a   Lauritzen, Brian ^a   Sørensen, Brit Binow ^a   Clausen, Jes Thorn ^a   Jespersgaard, Christina ^a   Krogh, Berit Olsen ^a   Bowler, Andrew Neil ^a   Breinholt, Jens ^a   Gruhler, Albrecht ^a   Svensson, L Anders ^a   Petersen, Helle Heibroch ^a   Petersen, Lars Christian ^a   Balling, Kristoffer W ^a   Hansen, Lene ^a   Hermit, Mette Brunsgaard ^a   Egebjerg, Thomas ^a   Friederichsen, Birgitte ^a   Ezban, Mirella ^a   Bjørn, Søren Erik ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7A; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2021; SERINE PROTEINASE INHIBITOR; TISSUE FACTOR PATHWAY INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; CONTROLLED STUDY; DRUG PROTEIN BINDING; EXPERIMENTAL RABBIT; FEMALE; HEMOPHILIA; HEMOSTASIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PLASMA; PRIORITY JOURNAL; SINGLE DRUG DOSE; X RAY CRYSTALLOGRAPHY;

EID: 84862499521     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-401620     Document Type: Article

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