-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010; 60: 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
2
-
-
84862493601
-
-
Cancer Facts & Figures 2010, American Cancer Society. 2010
-
Cancer Facts & Figures 2010, American Cancer Society. 2010.
-
-
-
-
3
-
-
3042824049
-
Pancreaticoduodenectomy: a 20-year experience in 516 patients
-
discussion 725-717
-
Schmidt CM, Powell ES, Yiannoutsos CT, Howard TJ, Wiebke EA, Wiesenauer CA, Baumgardner JA, Cummings OW, Jacobson LE, Broadie TA, Canal DF, Goulet RJ, Jr., Curie EA, Cardenes H, Watkins JM, Loehrer PJ, Lillemoe KD, Madura JA. Pancreaticoduodenectomy: a 20-year experience in 516 patients. Arch Surg 2004; 139: 718-725; discussion 725-717.
-
(2004)
Arch Surg
, vol.139
, pp. 718-725
-
-
Schmidt, C.M.1
Powell, E.S.2
Yiannoutsos, C.T.3
Howard, T.J.4
Wiebke, E.A.5
Wiesenauer, C.A.6
Baumgardner, J.A.7
Cummings, O.W.8
Jacobson, L.E.9
Broadie, T.A.10
Canal, D.F.11
Goulet Jr., R.J.12
Curie, E.A.13
Cardenes, H.14
Watkins, J.M.15
Loehrer, P.J.16
Lillemoe, K.D.17
Madura, J.A.18
-
4
-
-
0034329115
-
Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators
-
Sohn TA, Yeo CJ, Cameron JL, Koniaris L, Kaushal S, Abrams RA, Sauter PK, Coleman J, Hruban RH, Lillemoe KD. Resected adenocarcinoma of the pancreas-616 patients: results, outcomes, and prognostic indicators. J Gastrointest Surg 2000; 4: 567-579.
-
(2000)
J Gastrointest Surg
, vol.4
, pp. 567-579
-
-
Sohn, T.A.1
Yeo, C.J.2
Cameron, J.L.3
Koniaris, L.4
Kaushal, S.5
Abrams, R.A.6
Sauter, P.K.7
Coleman, J.8
Hruban, R.H.9
Lillemoe, K.D.10
-
5
-
-
0029002348
-
Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients
-
discussion 731-723
-
Yeo CJ, Cameron JL, Lillemoe KD, Sitzmann JV, Hruban RH, Goodman SN, Dooley WC, Coleman J, Pitt HA. Pancreaticoduodenectomy for cancer of the head of the pancreas. 201 patients. Ann Surg 1995; 221: 721-731; discussion 731-723.
-
(1995)
Ann Surg
, vol.221
, pp. 721-731
-
-
Yeo, C.J.1
Cameron, J.L.2
Lillemoe, K.D.3
Sitzmann, J.V.4
Hruban, R.H.5
Goodman, S.N.6
Dooley, W.C.7
Coleman, J.8
Pitt, H.A.9
-
6
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first- line therapy for patients with advanced pancreas cancer: a randomized trial [see comments]
-
Burris HA, 3rd, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P, Nelson R, Dorr FA, Stephens CD, Von Hoff DD. Improvements in survival and clinical benefit with gemcitabine as first- line therapy for patients with advanced pancreas cancer: a randomized trial [see comments]. J Clin Oncol 1997; 15: 2403-2413.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris 3rd, H.A.1
Moore, M.J.2
Andersen, J.3
Green, M.R.4
Rothenberg, M.L.5
Modiano, M.R.6
Cripps, M.C.7
Portenoy, R.K.8
Storniolo, A.M.9
Tarassoff, P.10
Nelson, R.11
Dorr, F.A.12
Stephens, C.D.13
von Hoff, D.D.14
-
7
-
-
0028981050
-
Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B
-
Lin YC, Brown K, Siebenlist U. Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B. Proc Natl Acad Sci U S A 1995; 92: 552-556.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 552-556
-
-
Lin, Y.C.1
Brown, K.2
Siebenlist, U.3
-
8
-
-
0038621384
-
Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death
-
Arlt A, Gehrz A, Muerkoster S, Vorndamm J, Kruse ML, Folsch UR, Schafer H. Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. Oncogene 2003; 22: 3243-3251.
-
(2003)
Oncogene
, vol.22
, pp. 3243-3251
-
-
Arlt, A.1
Gehrz, A.2
Muerkoster, S.3
Vorndamm, J.4
Kruse, M.L.5
Folsch, U.R.6
Schafer, H.7
-
9
-
-
0037457422
-
Usage of the NF-kappaB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer
-
Muerkoster S, Arlt A, Witt M, Gehrz A, Haye S, March C, Grohmann F, Wegehenkel K, Kalthoff H, Folsch UR, Schafer H. Usage of the NF-kappaB inhibitor sulfasalazine as sensitizing agent in combined chemotherapy of pancreatic cancer. Int J Cancer 2003; 104: 469-476.
-
(2003)
Int J Cancer
, vol.104
, pp. 469-476
-
-
Muerkoster, S.1
Arlt, A.2
Witt, M.3
Gehrz, A.4
Haye, S.5
March, C.6
Grohmann, F.7
Wegehenkel, K.8
Kalthoff, H.9
Folsch, U.R.10
Schafer, H.11
-
10
-
-
0032943591
-
The nuclear factorkappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells
-
Wang W, Abbruzzese JL, Evans DB, Larry L, Cleary KR, Chiao PJ. The nuclear factorkappa B RelA transcription factor is constitutively activated in human pancreatic adenocarcinoma cells. Clin Cancer Res 1999; 5: 119-127.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 119-127
-
-
Wang, W.1
Abbruzzese, J.L.2
Evans, D.B.3
Larry, L.4
Cleary, K.R.5
Chiao, P.J.6
-
11
-
-
41149089359
-
The role of nuclear factor kappaB in pancreatic cancer and the clinical applications of targeted therapy
-
Holcomb B, Yip-Schneider M, Schmidt CM. The role of nuclear factor kappaB in pancreatic cancer and the clinical applications of targeted therapy. Pancreas 2008; 36: 225-235.
-
(2008)
Pancreas
, vol.36
, pp. 225-235
-
-
Holcomb, B.1
Yip-Schneider, M.2
Schmidt, C.M.3
-
12
-
-
18044376489
-
Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells
-
Yip-Schneider MT, Nakshatri H, Sweeney CJ, Marshall MS, Wiebke EA, Schmidt CM. Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. Mol Cancer Ther 2005; 4: 587-594.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 587-594
-
-
Yip-Schneider, M.T.1
Nakshatri, H.2
Sweeney, C.J.3
Marshall, M.S.4
Wiebke, E.A.5
Schmidt, C.M.6
-
13
-
-
67650311657
-
Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1)
-
Neelakantan S, Nasim S, Guzman ML, Jordan CT, Crooks PA. Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1). Bioorg Med Chem Lett 2009; 19: 4346-4349.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 4346-4349
-
-
Neelakantan, S.1
Nasim, S.2
Guzman, M.L.3
Jordan, C.T.4
Crooks, P.A.5
-
14
-
-
58149359316
-
Effect of celecoxib and the novel anti-cancer agent, dimethylaminoparthenolide, in a developmental model of pancreatic cancer
-
Yip-Schneider MT, Wu H, Njoku V, Ralstin M, Holcomb B, Crooks PA, Neelakantan S, Sweeney CJ, Schmidt CM. Effect of celecoxib and the novel anti-cancer agent, dimethylaminoparthenolide, in a developmental model of pancreatic cancer. Pancreas 2008; 37: e45-53.
-
(2008)
Pancreas
, vol.37
-
-
Yip-Schneider, M.T.1
Wu, H.2
Njoku, V.3
Ralstin, M.4
Holcomb, B.5
Crooks, P.A.6
Neelakantan, S.7
Sweeney, C.J.8
Schmidt, C.M.9
-
15
-
-
34250703218
-
Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo
-
Yip-Schneider MT, Wu H, Ralstin M, Yiannoutsos C, Crooks PA, Neelakantan S, Noble S, Nakshatri H, Sweeney CJ, Schmidt CM. Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo. Mol Cancer Ther 2007; 6: 1736-1744.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1736-1744
-
-
Yip-Schneider, M.T.1
Wu, H.2
Ralstin, M.3
Yiannoutsos, C.4
Crooks, P.A.5
Neelakantan, S.6
Noble, S.7
Nakshatri, H.8
Sweeney, C.J.9
Schmidt, C.M.10
-
16
-
-
47749086343
-
Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies
-
Holcomb B, Yip-Schneider MT, Matos JM, Dixon J, Kennard J, Mahomed J, Shanmugam R, Sebolt-Leopold J, Schmidt CM. Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies. J Gastrointest Surg 2008; 12: 288-296.
-
(2008)
J Gastrointest Surg
, vol.12
, pp. 288-296
-
-
Holcomb, B.1
Yip-Schneider, M.T.2
Matos, J.M.3
Dixon, J.4
Kennard, J.5
Mahomed, J.6
Shanmugam, R.7
Sebolt-Leopold, J.8
Schmidt, C.M.9
-
17
-
-
77952420656
-
Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo
-
Wang SJ, Gao Y, Chen H, Kong R, Jiang HC, Pan SH, Xue DB, Bai XW, Sun B. Dihydroartemisinin inactivates NF-kappaB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo. Cancer Lett 2010; 293: 99-108.
-
(2010)
Cancer Lett
, vol.293
, pp. 99-108
-
-
Wang, S.J.1
Gao, Y.2
Chen, H.3
Kong, R.4
Jiang, H.C.5
Pan, S.H.6
Xue, D.B.7
Bai, X.W.8
Sun, B.9
-
18
-
-
1842609941
-
Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: implications for therapy in pancreatic cancer
-
Fahy BN, Schlieman MG, Virudachalam S, Bold RJ. Inhibition of AKT abrogates chemotherapy-induced NF-kappaB survival mechanisms: implications for therapy in pancreatic cancer. J Am Coll Surg 2004; 198: 591-599.
-
(2004)
J Am Coll Surg
, vol.198
, pp. 591-599
-
-
Fahy, B.N.1
Schlieman, M.G.2
Virudachalam, S.3
Bold, R.J.4
-
19
-
-
77953703732
-
Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer
-
Harikumar KB, Kunnumakkara AB, Sethi G, Diagaradjane P, Anand P, Pandey MK, Gelovani J, Krishnan S, Guha S, Aggarwal BB. Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer. Int J Cancer 2010; 127: 257-268.
-
(2010)
Int J Cancer
, vol.127
, pp. 257-268
-
-
Harikumar, K.B.1
Kunnumakkara, A.B.2
Sethi, G.3
Diagaradjane, P.4
Anand, P.5
Pandey, M.K.6
Gelovani, J.7
Krishnan, S.8
Guha, S.9
Aggarwal, B.B.10
-
20
-
-
39649125467
-
An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells
-
Guzman ML, Rossi RM, Neelakantan S, Li X, Corbett CA, Hassane DC, Becker MW, Bennett JM, Sullivan E, Lachowicz JL, Vaughan A, Sweeney CJ, Matthews W, Carroll M, Liesveld JL, Crooks PA, Jordan CT. An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells. Blood 2007; 110: 4427-4435.
-
(2007)
Blood
, vol.110
, pp. 4427-4435
-
-
Guzman, M.L.1
Rossi, R.M.2
Neelakantan, S.3
Li, X.4
Corbett, C.A.5
Hassane, D.C.6
Becker, M.W.7
Bennett, J.M.8
Sullivan, E.9
Lachowicz, J.L.10
Vaughan, A.11
Sweeney, C.J.12
Matthews, W.13
Carroll, M.14
Liesveld, J.L.15
Crooks, P.A.16
Jordan, C.T.17
-
21
-
-
79953284393
-
A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-kappaB and generating reactive oxygen species
-
Shanmugam R, Kusumanchi P, Appaiah H, Cheng L, Crooks P, Neelakantan S, Peat T, Klaunig J, Matthews W, Nakshatri H, Sweeney CJ. A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-kappaB and generating reactive oxygen species. Int J Cancer 2010.
-
(2010)
Int J Cancer
-
-
Shanmugam, R.1
Kusumanchi, P.2
Appaiah, H.3
Cheng, L.4
Crooks, P.5
Neelakantan, S.6
Peat, T.7
Klaunig, J.8
Matthews, W.9
Nakshatri, H.10
Sweeney, C.J.11
-
22
-
-
77953371413
-
A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFkappaB and generating reactive oxygen species
-
Shanmugam R, Kusumanchi P, Cheng L, Crooks P, Neelakantan S, Matthews W, Nakshatri H, Sweeney CJ. A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFkappaB and generating reactive oxygen species. Prostate 2010; 70: 1074-1086.
-
(2010)
Prostate
, vol.70
, pp. 1074-1086
-
-
Shanmugam, R.1
Kusumanchi, P.2
Cheng, L.3
Crooks, P.4
Neelakantan, S.5
Matthews, W.6
Nakshatri, H.7
Sweeney, C.J.8
-
23
-
-
77953460179
-
Natural and synthetic alpha, betaunsaturated carbonyls for NF-kB inhibition
-
Ramachandran P, Yip-Schneider, MT, Schmidt, CM. Natural and synthetic alpha, betaunsaturated carbonyls for NF-kB inhibition. Future Medicinal Chemistry 2009; 1: 177-198.
-
(2009)
Future Medicinal Chemistry
, vol.1
, pp. 177-198
-
-
Ramachandran, P.1
Yip-Schneider, M.T.2
Schmidt, C.M.3
-
24
-
-
77958068349
-
Tailored alpha-methylene-gamma-butyrolactones and their effects on growth suppression in pancreatic carcinoma cells
-
Ramachandran PV, Pratihar D, Nair HN, Walters M, Smith S, Yip-Schneider MT, Wu H, Schmidt CM. Tailored alpha-methylene-gamma-butyrolactones and their effects on growth suppression in pancreatic carcinoma cells. Bioorg Med Chem Lett 2010.
-
(2010)
Bioorg Med Chem Lett
-
-
Ramachandran, P.V.1
Pratihar, D.2
Nair, H.N.3
Walters, M.4
Smith, S.5
Yip-Schneider, M.T.6
Wu, H.7
Schmidt, C.M.8
|