Expression of vascular endothelial growth factor-C in gastric carcinoma and the effect of its antisense gene transfection on the proliferation of human gastric cancer cell line SGC-7901

American Journal of Surgery

Volumn 204, Issue 1, 2012, Pages 78-83

  Zhu, Peng ^a   Zhang, Jianbo ^a   Chen, Qi ^a   Wang, Jijian ^a   Wang, Yaxu ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Antisense eukaryotic expression vector; Human gastric cancer cell line; Lymphangiogenesis; Transfection; Vascular endothelial growth factor C

Indexed keywords

COMPLEMENTARY RNA; MESSENGER RNA; VASCULOTROPIN C;

ADULT; AGED; ANTISENSE THERAPY; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CANCER RECURRENCE; CANCER TISSUE; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPH NODE METASTASIS; LYMPHANGIOGENESIS; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECOMBINANT PLASMID; STOMACH CARCINOMA;

ADULT; AGED; BLOTTING, WESTERN; CARCINOMA; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHANGIOGENESIS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; PLASMIDS; POLYMERASE CHAIN REACTION; RNA, ANTISENSE; RNA, MESSENGER; STOMACH NEOPLASMS; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

EID: 84862495515     PISSN: 00029610     EISSN: 18791883     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2011.06.056     Document Type: Article

References (18)

1. Yonemura Y, Endo Y, Tabata K, et al. Role of VEGF-C and VEGF-D in lymphangiogenesis in gastric cancer. Int J Clin Oncol 2005;10: 318-27. (Pubitemid 41507205)
2. Jennbacken K, Vallbo C, Wang W, et al. Expression of vascular endothelial growth factor C (VEGF-C) and VEGF receptor-3 in human prostate cancer is associated with regional lymph node metastasis. Prostate 2005;65:110-6. (Pubitemid 41362277)
3. Garcia EA, Simões K, Wakamatsu A, et al. Lymphatic vessel density and VEGF-C expression are significantly different among benign and malignant thyroid lesions. Endocr Pathol 2010;21:101-7.
4. Nakamura M. Suppression of lymphangiogenesis induced by Flt-4 antibody in gastric low-grade mucosa-associated lymphoid tissue lymphoma by Helicobacter heilmannii infection. Gastroenterol Hepatol 2010;5:S1-6.
5. Kemik O, Sumer A, Kemik AS, et al. The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer. World J Surg Oncol 2010;28:85.
6. Looney M, Doran P, Buggy DJ. Effect of anesthetic technique on serum vascular endothelial growth factor C and transforming growth factor β in women undergoing anesthesia and surgery for breast cancer. Anesthesiology 2010;113:1118-25.
7. Gajanin V, Krivokuća Z, Kostić K, et al. Significance of vascular endothelial growth factor expression in skin melanoma. Vojnosanit Pregl 2010;67:747-54.
8. Anagiri T, Oyama T, Yasumoto K. Association between lymphangiogenesis-/ micrometastasis- and adhesion-related molecules in resected stage I NSCLC.Lung. Cancer 2010;70:320-8.
9. Kristiina I, Karkkainen MJ, Lawrence EC, et al. VEGFR3 gene structure, regulatory region, and sequence polymorphisms. FASEB J 2001; 15:1028-36. (Pubitemid 32290791)
10. Feng Y, Wang W, Hu J, et al. Expression of VEGF-C and VEGF-D as significant markers for assessment of lymphangiogenesis and lymph node metastasis in non-small cell lung cancer. Anat Rec 2010;293: 802-12.
11. Kodama M, Kitadai Y, Tanaka M, et al. Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms. Clin Cancer Res 2008;14: 7205-14.
12. Dadras SS, Detmar M. Angiogenesis and lymphangiogenesis of skin cancers. Hematol Oncol Clin North Am 2004;18:1059-70. (Pubitemid 39335759)
13. Kösem M, Tuncer I, Kotan C, et al. Significance of VEGF and microvascular density in gastric carcinoma. Hepatogastroenterology 2009;56:1236-40.
14. Aurello P, Rossi Del Monte S, D'Angelo F, et al. Vascular endothelial growth factor C and microvessel density in gastric carcinoma: correlation with clinicopathological factors. Our experience and review of the literature. Oncol Res 2009;17:405-11.
15. Hirakawa S, Kodama S, Kunstfeld R, et al. VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med 2005;201:1089-99. (Pubitemid 40524677)
16. Dadras SS, Lange-Asschenfeldt B, Velasco P, et al. Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes. Mod Pathol 2005;18:1232-42. (Pubitemid 43079923)
17. Koyama Y, Kaneko K, Akazawa K, et al. Vascular endothelial growth factor C and vascular endothelial growth factor D messenger RNA expression in breast cancer: association with lymph node metastasis. Clin Breast Cancer 2003;4:354-60. (Pubitemid 38139591)
18. Wang XL, Fang JP, Tang RY, et al. Different significance between intratumoral and peritumoral lymphatic vessel density in gastric cancer: a retrospective study of 123 cases. BMC Cancer 2010;10: 299.