Elastin-derived peptides increase invasive capacities of lung cancer cells by post-transcriptional regulation of MMP-2 and uPA

Clinical and Experimental Metastasis

Volumn 29, Issue 5, 2012, Pages 511-522

  Toupance, Simon ^a   Brassart, Bertrand ^a   Rabenoelina, Fanja ^a   Ghoneim, Christelle ^b   Vallar, Laurent ^b   Polette, Myriam ^a,c   Debelle, Laurent ^a   Birembaut, Philippe ^a,c  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^c HÔPITAL MAISON BLANCHE   (France)

Author keywords

Cell invasion; Elastin derived peptides; Lung cancer; Matrix metalloproteinases; Urokinase

Indexed keywords

DACTINOMYCIN; EDASTIN DERIVED PEPTIDE; ELASTIN; GELATINASE A; UNCLASSIFIED DRUG; UROKINASE; GALECTIN 3; MESSENGER RNA; OLIGOPEPTIDE; TUMOR MARKER; VITRONECTIN RECEPTOR;

ARTICLE; CANCER CELL CULTURE; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME RELEASE; HUMAN; HUMAN CELL; LUNG CANCER; TUMOR GROWTH; UPREGULATION; ADENOCARCINOMA; CELL MOTION; DNA MICROARRAY; DRUG EFFECT; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING; WESTERN BLOTTING;

ADENOCARCINOMA; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; ELASTIN; EXTRACELLULAR MATRIX; GALECTIN 3; GENE EXPRESSION PROFILING; HUMANS; INTEGRIN ALPHAVBETA3; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 2; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OLIGOPEPTIDES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84862339484     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-012-9467-3     Document Type: Article

References (55)

1. Kielty CM, Sherratt MJ, Shuttleworth CA (2002) Elastic fibres. J Cell Sci 115:2817-2828
2. Mithieux SM, Weiss AS (2005) Elastin. Adv Protein Chem 70:437-461 (Pubitemid 40544790)
3. Shapiro SD, Endicott SK, Province MA et al (1991) Marked longevity of human lung parenchymal elastic fibers deduced from prevalence of D-aspartate and nuclear weapons-related radiocarbon. J Clin Invest 87:1828-1834
4. Werb Z, Banda MJ, McKerrow JH et al (1982) Elastases and elastin degradation. J Invest Dermatol 79(Suppl 1):154s-159s (Pubitemid 12080842)
5. Lapis K, Tímár J (2002) Role of elastin-matrix interactions in tumor progression. Semin Cancer Biol 12:209-217 (Pubitemid 34833064)
6. Mecham RP, Hinek A, Griffin GL et al (1989) The elastin receptor shows structural and functional similarities to the 67-kDa tumor cell laminin receptor. J Biol Chem 264:16652-16657 (Pubitemid 19243559)
7. Mochizuki S, Brassart B, Hinek A (2002) Signaling pathways transduced through the elastin receptor facilitate proliferation of arterial smooth muscle cells. J Biol Chem 277:44854-44863 (Pubitemid 36159080)
8. Robinet A, Fahem A, Cauchard J-H et al (2005) Elastin-derived peptides enhance angiogenesis by promoting endothelial cell migration and tubulogenesis through upregulation of MT1-MMP. J Cell Sci 118:343-356 (Pubitemid 40277347)
9. Maeda I, Mizoiri N, Briones MPP et al (2007) Induction of macrophage migration through lactose-insensitive receptor by elastin-derived nonapeptides and their analog. J Pept Sci 13: 263-268 (Pubitemid 46638197)
10. Grosso LE, Scott M (1993) PGAIPG, a repeated hexapeptide of bovine and human tropoelastin, is chemotactic for neutrophils and Lewis lung carcinoma cells. Arch Biochem Biophys 305: 401-404 (Pubitemid 23282923)
11. Hauck M, Seres I, Kiss I et al (1995) Effects of synthesized elastin peptides on human leukocytes. Biochem Mol Biol Int 37:45-55 (Pubitemid 26177876)
12. Senior RM, Griffin GL, Mecham RP et al (1984) Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J Cell Biol 99:870-874 (Pubitemid 14043344)
13. Debret R, Antonicelli F, Theill A et al (2005) Elastin-derived peptides induce a T-helper type 1 polarization of human blood lymphocytes. Arterioscler Thromb Vasc Biol 25:1353-1358 (Pubitemid 40923351)
14. Brassart B, Randoux A, Hornebeck W et al (1998) Regulation of matrix metalloproteinase-2 (gelatinase A, MMP-2), membranetype matrix metalloproteinase-1 (MT1-MMP) and tissue inhibitor of metalloproteinases-2 (TIMP-2) expression by elastin-derived peptides in human HT-1080 fibrosarcoma cell line. Clin Exp Metastasis 16:489-500 (Pubitemid 29009585)
15. Ntayi C, Labrousse A-L, Debret R et al (2004) Elastin-derived peptides upregulate matrix metalloproteinase-2-mediated melanoma cell invasion through elastin-binding protein. J Invest Dermatol 122:256-265 (Pubitemid 38281042)
16. Jung S, Hinek A, Tsugu A et al (1999) Astrocytoma cell interaction with elastin substrates: implications for astrocytoma invasive potential. Glia 25:179-189 (Pubitemid 29032773)
17. Hinek A, Jung S, Rutka JT (1999) Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells. Acta Neuropathol 97:399-407 (Pubitemid 29134521)
18. Pocza P, Süli-Vargha H, Darvas Z et al (2008) Locally generated VGVAPG and VAPG elastin-derived peptides amplify melanoma invasion via the galectin-3 receptor. Int J Cancer 122:1972-1980 (Pubitemid 351441185)
19. Long MM, King VJ, Prasad KU et al (1989) Elastin repeat peptides as chemoattractants for bovine aortic endothelial cells. J Cell Physiol 140:512-518 (Pubitemid 19241768)
20. Brassart B, Fuchs P, Huet E et al (2001) Conformational dependence of collagenase (matrix metalloproteinase-1) up-regulation by elastin peptides in cultured fibroblasts. J Biol Chem 276:5222-5227
21. Maquart F-X, Pasco S, Ramont L et al (2004) An introduction to matrikines: extracellular matrix-derived peptides which regulate cell activity. Implication in tumor invasion. Crit Rev Oncol Hematol 49:199-202 (Pubitemid 38251352)
22. Bisaccia F, Morelli MA, De Biasi M et al (1994) Migration of monocytes in the presence of elastolytic fragments of elastin and in synthetic derivates. Structure-activity relationships. Int J Pept Protein Res 44:332-341 (Pubitemid 24316885)
23. Castiglione Morelli MA, Bisaccia F, Spisani S et al (1997) Structure-activity relationships for some elastin-derived peptide chemoattractants. J Pept Res 49:492-499 (Pubitemid 27334993)
24. Bisaccia F, Castiglione-Morelli MA, Spisani S et al (1998) The amino acid sequence coded by the rarely expressed exon 26A of human elastin contains a stable beta-turn with chemotactic activity for monocytes. Biochemistry 37:11128-11135 (Pubitemid 28368940)
25. Hinek A, Wrenn DS, Mecham RP et al (1988) The elastin receptor: a galactoside-binding protein. Science 239:1539-1541
26. Mecham RP, Hinek A, Entwistle R et al (1989) Elastin binds to a multifunctional 67-kilodalton peripheral membrane protein. Biochemistry 28:3716-3722 (Pubitemid 19125413)
27. Privitera S, Prody CA, Callahan JW et al (1998) The 67-kDa enzymatically inactive alternatively spliced variant of betagalactosidase is identical to the elastin/laminin-binding protein. J Biol Chem 273:6319-6326 (Pubitemid 28144722)
28. Duca L, Blanchevoye C, Cantarelli B et al (2007) The elastin receptor complex transduces signals through the catalytic activity of its Neu-1 subunit. J Biol Chem 282:12484-12491 (Pubitemid 47100624)
29. Floquet N, Héry-Huynh S, Dauchez M et al (2004) Structural characterization of VGVAPG, an elastin-derived peptide. Biopolymers 76:266-280 (Pubitemid 38724854)
30. Fuchs PFJ, Bonvin AMJJ, Bochicchio B et al (2006) Kinetics and thermodynamics of type VIII beta-turn formation: a CD, NMR, and microsecond explicit molecular dynamics study of the GDNP tetrapeptide. Biophys J 90:2745-2759
31. Moroy G, Alix AJP, Héry-Huynh S (2005) Structural characterization of human elastin derived peptides containing the GXXP sequence. Biopolymers 78:206-220 (Pubitemid 41140775)
32. Plow EF, Haas TA, Zhang L et al (2000) Ligand binding to integrins. J Biol Chem 275:21785-21788 (Pubitemid 30621742)
33. Humphries JD, Byron A, Humphries MJ (2006) Integrin ligands at a glance. J Cell Sci 119:3901-3903 (Pubitemid 44650863)
34. Bax DV, Rodgers UR, Bilek MMM et al (2009) Cell adhesion to tropoelastin is mediated via the C-terminal GRKRK motif and integrin alphaVbeta3. J Biol Chem 284:28616-28623
35. Ochieng J, Furtak V, Lukyanov P (2004) Extracellular functions of galectin-3. Glycoconj J 19:527-535 (Pubitemid 38316526)
36. Wang Y, Nangia-Makker P, Tait L et al (2009) Regulation of prostate cancer progression by galectin-3. Am J Pathol 174: 1515-1523
37. Ochieng J, Warfield P, Green-Jarvis B et al (1999) Galectin-3 regulates the adhesive interaction between breast carcinoma cells and elastin. J Cell Biochem 75:505-514 (Pubitemid 29521657)
38. Devy J, Duca L, Cantarelli B et al (2010) Elastin-derived peptides enhance melanoma growth in vivo by upregulating the activation of Mcol-A (MMP-1) collagenase. Br J Cancer 103:1562-1570
39. Jacob M-P, Hornebeck W (1985) Isolation and characterization of insoluble and kappa-elastins. Front Matrix Biol 10:92-129
40. Irizarry RA, Hobbs B, Collin F et al (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4:249-264
41. Hinek A (1996) Biological roles of the non-integrin elastin/laminin receptor. Biol Chem 377:471-480
42. Cairns RA, Harris IS, Mak TW (2011) Regulation of cancer cell metabolism. Nat Rev Cancer 11:85-95
43. Timar J, Lapis K, Fulop T et al (1991) Interaction between elastin and tumor cell lines with different metastatic potential; in vitro and in vivo studies. J Cancer Res Clin Oncol 117:232-238
44. Timár J, Diczházi C, Ladányi A et al (1995) Interaction of tumour cells with elastin and the metastatic phenotype. Ciba Found Symp 192:321-335; discussion 335-337
45. Martinella-Catusse C, Polette M, Noel A et al (2001) Downregulation of MT1-MMP expression by the alpha3 chain of type IV collagen inhibits bronchial tumor cell line invasion. Lab Invest 81:167-175 (Pubitemid 32176380)
46. Niki T, Kohno T, Iba S et al (2002) Frequent co-localization of Cox-2 and laminin-5 gamma2 chain at the invasive front of earlystage lung adenocarcinomas. Am J Pathol 160:1129-1141 (Pubitemid 34224599)
47. Chang C, Werb Z (2001) The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol 11:S37-S43
48. Polette M, Nawrocki-Raby B, Gilles C et al (2004) Tumour invasion and matrix metalloproteinases. Crit Rev Oncol Hematol 49:179-186 (Pubitemid 38251350)
49. Sidenius N, Blasi F (2003) The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy. Cancer Metastasis Rev 22:205-222 (Pubitemid 36561058)
50. Senior RM, Griffin GL, Fliszar CJ et al (1991) Human 92- and 72-kilodalton type IV collagenases are elastases. J Biol Chem 266:7870-7875 (Pubitemid 21906446)
51. Dashevsky O, Varon D, Brill A (2009) Platelet-derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP-2 production. Int J Cancer 124:1773-1777
52. Angelucci A, D'Ascenzo S, Festuccia C et al (2000) Vesicleassociated urokinase plasminogen activator promotes invasion in prostate cancer cell lines. Clin Exp Metastasis 18:163-170 (Pubitemid 32165250)
53. Dolo V, D'Ascenzo S, Giusti I et al (2005) Shedding of membrane vesicles by tumor and endothelial cells. Ital J Anat Embryol 110:127-133 (Pubitemid 40993967)
54. Moisa A, Fritz P, Eck A et al (2007) Growth/adhesion-regulatory tissue lectin galectin-3: stromal presence but not cytoplasmic/nuclear expression in tumor cells as a negative prognostic factor in breast cancer. Anticancer Res 27:2131-2139 (Pubitemid 47228046)
55. Duca L, Floquet N, Alix AJP et al (2004) Elastin as a matrikine. Crit Rev Oncol Hematol 49:235-244 (Pubitemid 38251355)