Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 799-813

  Yu, Shann S ^a   Lau, Cheryl M ^a   Thomas, Susan N ^b   Gray Jerome, W ^c   Maron, David J ^c   Dickerson, James H ^a,d   Hubbell, Jeffrey A ^b   Giorgio, Todd D ^a,e  

^a VANDERBILT UNIVERSITY   (United States)

^b EPFL   (Switzerland)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d VANDERBILT UNIVERSITY   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Iron oxides; Macrophage targeting; Opsonization; Poly(ethylene glycol) (PEG); Poly(propylene sulfide) (PPS)

Indexed keywords

GELATINASE B; IRON OXIDE; MACROGOL; NANOPARTICLE; POLYMER; PROTEINASE; FERRIC ION; FERRIC OXIDE; FUCOIDIN; MACROGOL DERIVATIVE; POLY(ETHYLENE GLYCOL) STABILIZED POLY(PROPYLENE SULFIDE); POLY(ETHYLENE GLYCOL)-STABILIZED POLY(PROPYLENE SULFIDE); POLYSACCHARIDE; SULFIDE;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; MACROPHAGE FUNCTION; MATERIAL COATING; MICELLE; MICELLIZATION; NANOFABRICATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PREDICTION; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PROTEIN CLEAVAGE; SENSITIVITY ANALYSIS; STRUCTURE ANALYSIS; SURFACE CHARGE; ZETA POTENTIAL; CELL CULTURE; CHEMISTRY; MACROPHAGE; METABOLISM; SURFACE PROPERTY; TUMOR CELL LINE;

CELL LINE, TUMOR; CELLS, CULTURED; FERRIC COMPOUNDS; HUMANS; MACROPHAGES; MATRIX METALLOPROTEINASE 9; MICELLES; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYSACCHARIDES; SULFIDES; SURFACE PROPERTIES;

EID: 84862327507     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S28531     Document Type: Article

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