A model predicting delivery of saquinavir in nanoparticles to human monocyte/macrophage (Mo/Mac) cells

Biotechnology and Bioengineering

Volumn 101, Issue 5, 2008, Pages 1072-1082

  Gamsiz, D Ece ^a   Shah, Lipa K ^b,c   Devalapally, Harikrishna ^b   Amiji, Mansoor M ^b   Carrier, Rebecca L ^a  

^a Northeastern University   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Drug delivery; Modeling; Nanoparticles; PEO PCL; THP 1 Mo Mac cells

Indexed keywords

CELLS; CONCENTRATION (PROCESS); CYTOLOGY; DRUG DELIVERY; ETHYLENE; FORECASTING; NANOSTRUCTURED MATERIALS; NANOSTRUCTURES; POLYETHYLENE OXIDES; SOLUTIONS;

AQUEOUS SOLUTIONS; CAPROLACTONE; CULTURED CELLS; DRUG CONCENTRATIONS; DRUG RELEASES; FORMULATION DESIGNS; INTRACELLULAR CONCENTRATIONS; INTRACELLULAR DELIVERIES; KEY PROCESSES; KEY SYSTEMS; MATHEMATICAL EXPRESSIONS; MODELING; NANOPARTICLE SYSTEMS; PEO-PCL; POLY(ETHYLENE OXIDE); RELATIVE KINETICS; SAQUINAVIR; SIMPLE MODELS; THP-1 MO/MAC CELLS;

NANOPARTICLES;

MACROGOL; NANOPARTICLE; POLYCAPROLACTONE; SAQUINAVIR;

AQUEOUS SOLUTION; ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG UPTAKE; HUMAN; HUMAN CELL; MACROPHAGE; MATHEMATICAL MODEL; MONOCYTE;

BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; HIV PROTEASE INHIBITORS; HUMANS; KINETICS; MODELS, BIOLOGICAL; MONOCYTES; NANOPARTICLES; PARTICLE SIZE; POLYESTERS; SAQUINAVIR; SOLUBILITY;

EID: 56449114180     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21958     Document Type: Article

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