Significant activity of ecdysteroids on the resistance to doxorubicin in mammalian cancer cells expressing the human ABCB1 transporter

Journal of Medicinal Chemistry

Volumn 55, Issue 11, 2012, Pages 5034-5043

  Martins, Ana ^a   Tóth, Noémi ^a   Ványolós, Attila ^a   Béni, Zoltán ^b   Zupkó, István ^c   Molnár, József ^a,d   Báthori, Mária ^a   Hunyadi, Attila ^a,d  

^a UNIVERSITY OF SZEGED   (Hungary)

^b GEDEON RICHTER LTD   (Hungary)

^c UNIVERSITY OF SZEGED   (Hungary)

^d EUROPEAN COMMISSION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXY 22 DEOXY 20,21 DIDEHYDROECDYSONE; 14 EPI 20 HYDROXYECDYSONE; 2 DEOXY 5ALPHA INTEGRISTERONE A; 2 DEOXY 5ALPHA POLYPODINE B; 2 DEOXY ECDYSTERONE; 2 DEOXY ECDYSTERONE 25 GLUCOSIDE; 2 DEOXYECDYSONE; 22 DEOXY 20,21 DIDEHYDROECDYSONE; 22 DEOXY ECDYSTERONE; 22 DEOXYINTEGRISTERONE A; 25 HYDROXYDACRIHAINANSTERONE; 25,26 DIDEHYDRODACRYHAINANSTERONE; 3 EPI BETA ECDYSONE; 5ALPHA 20 HYDROXYECDYSONE; AJUGASTERONE C; DACRYHAINANSTERONE; DOXORUBICIN; ECDYSONE; ECDYSTEROID; ECDYSTERONE; INTEGRISTERONE A; MAKISTERONE C; MULTIDRUG RESISTANCE PROTEIN 1; MURISTERONE A; POLYPODINE B; PONASTERONE A; PTEROSTERONE; RHODAMINE 123; TURKESTERONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG POTENTIATION; DRUG RESISTANCE; DRUG STRUCTURE; LEUKEMIA L 5178 Y; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DOXORUBICIN; DRUG ANTAGONISM; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; ECDYSTEROIDS; HUMANS; MICE; P-GLYCOPROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862298709     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300424n     Document Type: Article

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