Isolation of bitter acids from hops (Humulus lupulus L.) using countercurrent chromatography

Journal of Separation Science

Volumn 35, Issue 9, 2012, Pages 1183-1189

  Dahlberg, Clinton J ^a   Harris, Guy ^b   Urban, Jan ^a   Tripp, Matthew L ^a   Bland, Jeffrey S ^a   Carroll, Brian J ^a  

^a Metagenics Inc   (United States)

^b Dynamic Extractions Inc   (United States)

Author keywords

Countercurrent chromatography; Hops; Iso acids; Isohumulone; Tetrahydro iso acids

Indexed keywords

ACID EXTRACTS; ALTERNATIVE PROCEDURES; AQUEOUS BUFFER; CATALYTIC HYDROGENATION; COUNTERCURRENT CHROMATOGRAPHY; CRITICAL VARIABLES; DIASTEREOMERS; HOPS; ISOHUMULONE; SOLVENT SYSTEM;

HEXANE; HYDROGENATION; PURIFICATION; SOLVENTS;

LIQUID CHROMATOGRAPHY;

BETA CYCLODEXTRIN; HEXANE; HUMULON; LUPULON;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL COMPOSITION; COUNTER CURRENT CHROMATOGRAPHY; HOPS; HYDROGENATION; ISOMERIZATION; PH; PRIORITY JOURNAL; PURIFICATION;

ACIDS; COUNTERCURRENT DISTRIBUTION; HUMULUS; ISOMERISM; PLANT EXTRACTS;

EID: 84862270959     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201101109     Document Type: Article

References (21)

1. Desai, A., Konda, V. R., Darland, G., Austin, M., Prabhu, K. S., Bland, J. S., Carroll, B. J., Tripp, M. L., Inflamm. Res. 2009, 58, 229-234.
2. Hall, A. J., Babish, J. G., Darland, G. K., Carroll, B. J., Konda, V. R., Lerman, R. H., Bland, J. S., Tripp, M. L., Phytochemistry 2008, 69, 1534-1547.
3. Konda, V. R., Desai, A., Darland, G., Bland, J. S., Tripp, M. L., J. Inflamm. 2009, 6, 26-35.
4. Konda, V. R., Desai, A., Darland, G., Bland, J. S., Tripp, M. L., Arthritis Rheum. 2010, 62, 1683-1692.
5. Rigby, F. L., Bethune, J. L., Proc. Am. Soc. Brew. Chem. 1952, 98-105.
6. Verzele, M., Dewaele, C., J. Am. Soc. Brew. Chem. 1981, 39, 67-69.
7. Burroughs, L. J., Williams, P. D., Eur. Brewing Convent. 1999, 27, 283-290.
8. Hughes, P. S., J. Chromatogr. A 1996, 731, 327-330.
9. Nord, L. I., Sorensen, S. B., Duus, J.O., Magn. Res. Chem. 2003, 41, 660-670.
10. Pusecker, K., Albert, K., Bayer, E., J. Chromatogr. A 1999, 836, 245-252.
11. Verzele, M., De Potter, M., J. Chromatogr. 1978, 166, 320- 326.
12. Sutherland, I. A., Fisher, D., J. Chromatogr. A 2009, 1216, 740-753.
13. Deamicis, C., Edwards, N. A., Giles, M. B., Harris, G. H., Hewitson, P., Janaway, L., Ignatova, S., J. Chromatogr. A 2011, 1218, 6122-6127.
14. Ito, Y., J. Chromatogr. A 2005, 1065, 145-168.
15. Pauli, G. F., Pro, S. M., Friesen, J. B., J. Nat. Prod. 2008, 71, 1489-1508.
16. Yuan, Y., Wang, B., Chen, L., Luo, H., Fisher, D., Sutherland, I. A., Wei, Y., J. Chromatogr. A 2008, 1194, 192-198.
17. Dahlberg, C. J., Traub, J. S., Tripp, M. L., Bland, J. S., Carroll, B. J., J. Sep. Sci. 2010, 33, 2828-2832.
18. Hermans-Lokkerbol, A. C. J., Hoek, A. C., Verpoorte, R., J. Chromatogr. A 1997, 771, 71-79.
19. Khatib, A., Wilson, E. G., Supardi, M., Verpoorte, R., Food. Chem. 2010, 119, 354-357.
20. Khatib, A., Wilson, E. G., Kim, H. K., Supardi, M., Choi, Y. H., Verpoorte, R., Phytochem. Anal. 2007, 18, 371-377.
21. Hermans-Lokkerbol, A. C. J., Verpoorte, R., J. Chromatogr. A 1994, 664, 45-53.