Upregulation of fibroblast growth factor receptor 2 and 3 in the late stages of fetal lung development in the nitrofen rat model

Pediatric Surgery International

Volumn 28, Issue 2, 2012, Pages 195-199

  Friedmacher, Florian ^a   Doi, Takashi ^a   Gosemann, Jan Hendrik ^a   Fujiwara, Naho ^a   Kutasy, Balazs ^a   Puri, Prem ^a,b  

^a OUR LADY S CHILDREN S HOSPITAL   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Congenital diaphragmatic hernia; Fetal lung development; Fibroblast growth factor receptors; Nitrofen; Pulmonary hypoplasia

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR 4; MESSENGER RNA; NITROFEN; OLIVE OIL; DIPHENYL ETHER DERIVATIVE; FGFR2 PROTEIN, RAT; FGFR3 PROTEIN, RAT; FIBROBLAST GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CESAREAN SECTION; CONFERENCE PAPER; CONGENITAL DIAPHRAGM HERNIA; CONTROLLED STUDY; FEMALE; FETUS; FETUS DEVELOPMENT; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; MESENCHYME; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; ARTICLE; BIOSYNTHESIS; BREEDING; CHEMICALLY INDUCED DISORDER; DIAPHRAGM HERNIA; DISEASE MODEL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LUNG; METABOLISM; ORGANOGENESIS; PREGNANCY; PRENATAL DEVELOPMENT; SPRAGUE DAWLEY RAT;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HERNIA, DIAPHRAGMATIC; IMMUNOHISTOCHEMISTRY; LUNG; ORGANOGENESIS; PHENYL ETHERS; PREGNANCY; PREGNANCY, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 2; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; RNA, MESSENGER; UP-REGULATION;

EID: 84862261393     PISSN: 01790358     EISSN: 14379813     Source Type: Journal    
DOI: 10.1007/s00383-011-2985-2     Document Type: Conference Paper

References (25)

1. Bohn D (2002) Congenital diaphragmatic hernia. Am J Respir Crit Care Med 166(7):911-915 (Pubitemid 35193217)
2. Stege G, Fenton A, Jaffray B (2003) Nihilism in the 1990s: the true mortality of congenital diaphragmatic hernia. Pediatrics 112(3 Pt 1):532-535 (Pubitemid 37082102)
3. Gosche JR, Islam S, Boulanger SC (2005) Congenital diaphragmatic hernia: searching for answers. Am J Surg 190(2):324-332 (Pubitemid 40967947)
4. Sabharwal AJ, Davis CF, Howatson AG (2000) Post-mortem findings in fetal and neonatal congenital diaphragmatic hernia. Eur J Pediatr Surg 10(2):96-99 (Pubitemid 30349348)
5. Noble BR, Babiuk RP, Clugston RD et al (2007) Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen. Am J Physiol Lung Cell Mol Physiol 293(4):1079-1087
6. Montedonico S, Nakazawa N, Puri P (2008) Congenital diaphragmatic hernia and retinoids: searching for an etiology. Pediatr Surg Int 24(7):755-761
7. Lebeche D, Malpel S, Cardoso WV (1999) Fibroblast growth factor interactions in the developing lung. Mech Dev 86(1-2): 125-136 (Pubitemid 29371749)
8. Warburton D, Schwarz M, Tefft D et al (2000) The molecular basis of lung morphogenesis. Mech Dev 92(1):55-81 (Pubitemid 30125962)
9. Dionne CA, Crumley G, Bellot F et al (1990) Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors. EMBO J 9(9): 2685-2692
10. Keegan K, Johnson DE, Williams LT et al (1991) Isolation of an additional member of the fibroblast growth factor receptor family, FGFR-3. Proc Natl Acad Sci USA 88(4):1095-1099 (Pubitemid 21916171)
11. Partanen J, Makela TP, Eerola E et al (1991) FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J 10(6):1347-1354 (Pubitemid 21905599)
12. Thisse B, Thisse C (2005) Functions and regulations of fibroblast growth factor signaling during embryonic development. Dev Biol 287(2):390-402 (Pubitemid 41636772)
13. Lin X, Buff EM, Perrimon N et al (1999) Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development 126(17):3715-3723 (Pubitemid 29440471)
14. Metzger RJ, Krasnow MA (1999) Genetic control of branching morphogenesis. Science 284(5420):1635-1639 (Pubitemid 29291366)
15. Teramoto H, Yoneda A, Puri P (2003) Gene expression of fibroblast growth factors 10 and 7 is downregulated in the lung of nitrofen-induced diaphragmatic hernia in rats. J Pediatr Surg 38(7):1021-1024 (Pubitemid 36828866)
16. Powell PP, Wang CC, Horinouchi H et al (1998) Differential expression of fibroblast growth factor receptors 1 to 4 and ligand genes in late fetal and early postnatal rat lung. Am J Respir Cell Mol Biol 19(4):563-572 (Pubitemid 128354237)
17. De Langhe SP, Carraro G, Warburton D et al (2006) Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung. Dev Biol 299(1):52-62 (Pubitemid 44550103)
18. Weinstein M, Xu X, Ohyama K et al (1998) FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125(18):3615-3623 (Pubitemid 28469962)
19. Cardoso WV (2001) Molecular regulation of lung development. Annu Rev Physiol 63:471-494 (Pubitemid 32304326)
20. Sekine K, Ohuchi H, Fujiwara M et al (1999) Fgf10 is essential for limb and lung formation. Nat Genet 21(1):138-141 (Pubitemid 29036301)
21. Ornitz DM, Xu J, Colvin JS et al (1996) Receptor specificity of the fibroblast growth factor family. J Biol Chem 271(25):15292-15297 (Pubitemid 26195013)
22. Han RN, Liu J, Tanswell AK et al (1992) Expression of basic fibroblast growth factor and receptor: immunolocalization studies in developing rat fetal lung. Pediatr Res 31(5):435-440
23. Moura RS, Coutinho-Borges JP, Pacheco AP et al (2011) FGF signaling pathway in the developing chick lung: expression and inhibition studies. PLoS One 6(3):17660
24. Peters KG, Werner S, Chen G et al (1992) Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development 114(1):233-243
25. Cool SM, Sayer RE, van Heumen WR et al (2002) Temporal and spatial expression of fibroblast growth factor receptor 4 isoforms in murine tissues. Histochem J 34(6-7):291-297 (Pubitemid 36543072)