Optimized Selection of Unrelated Subjects for Whole-Genome Sequencing Studies of Rare High-Penetrance Alleles

Genetic Epidemiology

Volumn 36, Issue 5, 2012, Pages 472-479

  Edwards, Todd L ^a   Li, Chun ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY   (United States)

Author keywords

Ancestry; Cryptic relatedness; Sequencing; Study design; Subject selection

Indexed keywords

ALLELE; ARTICLE; CHROMOSOME; CONTROLLED STUDY; GENE SEQUENCE; GENETIC ALGORITHM; GENETIC DATABASE; GENETIC SELECTION; GENOME ANALYSIS; GENOME SEQUENCE; GENOTYPE; HUMAN; SAMPLE SIZE; SEQUENCE ANALYSIS;

ALGORITHMS; ALLELES; AMISH; CASE-CONTROL STUDIES; COMPUTER SIMULATION; FEMALE; GENOME; GENOME, HUMAN; GENOTYPE; HUMANS; MALE; MODELS, GENETIC; MODELS, STATISTICAL; PEDIGREE; PENETRANCE; PHYLOGENY; RESEARCH DESIGN; SEQUENCE ANALYSIS, DNA;

EID: 84862259573     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.21641     Document Type: Article

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