Cysteine coordination of Pb(II) is involved in the PbrR-dependent activation of the lead-resistance promoter, PpbrA, from Cupriavidus metallidurans CH34

BMC Microbiology

Volumn 12, Issue , 2012, Pages

  Hobman, Jon L ^a,b   Julian, Daniel J ^a   Brown, Nigel L ^a,c  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Bacterial gene expression; Metal protein interactions; Metal resistance; Metalloregulation

Indexed keywords

BACTERIAL DNA; CYSTEINE; LEAD;

ARTICLE; CONTROLLED STUDY; CUPRIAVIDUS; CUPRIAVIDUS METALLIDURANS; DNA FOOTPRINTING; DNA SEQUENCE; NONHUMAN; OPEN READING FRAME; TRANSCRIPTION INITIATION;

CUPRIAVIDUS; CYSTEINE; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; LEAD; PLASMIDS; PROMOTER REGIONS, GENETIC; TRANS-ACTIVATORS;

BACTERIA (MICROORGANISMS); CUPRIAVIDUS METALLIDURANS;

EID: 84862255350     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-12-109     Document Type: Article

References (57)

1. Lead precipitation by Vibrio harveyi: evidence for novel quorum-sensing interactions. Mire CE, Tourjee JA, O'Brien WF, Ramanujachary KV, Hecht GB, Appl Environ Microbiol 2004 70 855 864 (Pubitemid 38568209)
2. Pb(II)-translocating P-type ATPases. Rensing C, Sun Y, Mitra B, Rosen BP, J Biol Chem 1998 49 32614 32617 (Pubitemid 28557642)
3. The ATP hydrolytic activity of purified ZntA, a Pb(II)/Cd(II)/Zn(II)- translocating ATPase from Escherichia coli. Sharma R, Rensing C, Rosen BP, Mitra B, J Biol Chem 2000 275 3873 3878 (Pubitemid 30094611)
4. Cloning and functional analysis of the pbr lead resistance determinant of Ralstonia metallidurans CH34. Borremans B, Hobman JL, Provoost A, Corbisier P, Brown NL, van der Lelie D, J Bacteriol 2001 183 5651 5658 (Pubitemid 32898612)
5. An efflux transporter PbrA and a phosphatase PbrB cooperate in a lead-resistance mechanism in bacteria. Hynninen A, Touzé T, Pitkänen L, Mengin-Lecreulx D, Virta M, Mol Microbiol 2009 74 384 394
6. Alcaligenes eutrophus CH34 is a facultative chemolithotroph with plasmid-bound resistance to heavy metals. Mergeay M, Nies D, Schlegel HG, Gerits J, Charles P, van Gijsegem F, J Bacteriol 1985 162 328 334 (Pubitemid 15095872)
7. Transcriptomic and proteomic analyses of the pMOL30-encoded copper resistance in Cupriavidus metallidurans strain CH34. Monchy S, Benotmane MA, Wattiez R, van Aelst S, Auquier V, Borremans B, Mergeay M, Taghavi S, van der Lelie D, Vallaeys T, Microbiology 2006 152 1765 1776
8. Ralstonia metallidurans, a bacterium specifically adapted to toxic metals: towards a catalogue of metal-responsive genes. Mergeay M, Monchy S, Vallaeys T, Auquier V, Benotmane A, Bertin P, Taghavi S, Dunn J, van der Lelie D, Wattiez R, FEMS Microbiol Rev 2003 27 385 410 (Pubitemid 36700436)
9. The iron/lead supertransporter family of Fe3+/Pb2+ uptake systems. Debut AJ, Dumay QC, Barabote RD, Saier MH, J Mol Microbiol Biotechnol 2006 11 1 9 (Pubitemid 44015598)
10. The MerR family of transcriptional regulators. Brown NL, Stoyanov JV, Kidd SP, Hobman JL, FEMS Microbiol Rev 2003 27 145 163 (Pubitemid 36694653)
11. Plasmids pMOL28 and pMOL30 of Cupriavidus metallidurans are specialized in the maximum viable response to heavy metals. Monchy S, Benotmane MA, Janssen P, Vallaeys T, Taghavi S, van der Lelie D, Mergeay M, J Bacteriol 2007 189 7417 7425 (Pubitemid 47557358)
12. Lead (II) resistance in Cupriavidus metallidurans CH34: interplay between plasmid and chromosomally-located functions. Taghavi S, Lesaulnier C, Monchy S, Wattier R, Mergeay M, van der Lelie D, Anthonie van Leeuwenhoek 2009 96 171 182
13. An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: Development of a fluorescent lead(II) probe. Chen P, Greenberg B, Taghavi S, Romano C, van der Lelie D, He C, Angew Chem Int Ed 2005 44 2715 2719 (Pubitemid 40689570)
14. Spectroscopic insights into lead (II) coordination by the selective lead(II)-binding protein PbrR691. Chen PR, Wasinger EC, Zhao J, van der Lelie D, Chen LX, He C, J Am Chem Soc 2007 129 12350 12351 (Pubitemid 47598208)
15. Transcriptional activation of MerR family promoters in Cupriavidus metallidurans CH34. Julian DJ, Kershaw CJ, Brown NL, Hobman JL, Anthonie van Leeuwenhoek 2009 96 149 159
16. Characterisation of CadR from Pseudomonas aeruginosa: a Cd(II)-responsive MerR homologue. Brocklehurst KR, Megit SJ, Morby AP, Biochem Biophys Res Commun 2003 308 234 239 (Pubitemid 36937171)
17. Chromosomal locus for cadmium resistance in Pseudomonas putida consisting of a cadmium transporting ATPase and a MerR family response regulator. Lee S-W, Glickman E, Cooksey D, Appl Environ Microbiol 2001 67 697 702
18. Transcriptional activation of an Escherichia coli copper efflux regulon by the chromosomal MerR homologue, CueR. Outten FW, Outten CE, Hale J, O'Halloran TV, J Biol Chem 2000 275 31024 31029
19. Control of copper homeostasis in Escherichia coli by a P-type ATPase, CopA, and a MerR-like transcriptional activator, CopR. Petersen C, Moller LB, Gene 2000 261 289 298 (Pubitemid 32146500)
20. CueR (YbbI) of Escherichia coli is a MerR family regulator controlling expression of the copper exporter CopA. Stoyanov JV, Hobman JL, Brown NL, Mol Microbiol 2001 39 502 511 (Pubitemid 32113519)
21. ActP controls copper homeostasis in Rhizobium leguminosarum bv. viciae and Sinorhizobium melliloti preventing low-pH induced copper toxicity. Reeve WG, Tiwari RP, Kale NB, Dilworth MJ, Glenn AR, Mol Microbiol 2002 43 981 991 (Pubitemid 34415721)
22. The SctR of Salmonella enterica serovar Typhimurium encoding a homologue of the MerR protein is involved in the copper-responsive regulation of cuiD. Kim JS, Kim MH, Joe MH, Song SS, Lee IS, Choi SY, FEMS Microbiol Lett 2002 210 99 103 (Pubitemid 34521956)
23. ZntR is a Zn(II)-responsive MerR-like transcriptional regulator of zntA in Escherichia coli. Brocklehurst KR, Hobman JL, Lawley B, Blank L, Marshall SJ, Brown NL, Morby AP, Mol Microbiol 1999 31 893 902 (Pubitemid 29057291)
24. DNA distortion mechanism for transcriptional activation by ZntR, a Zn(II)-responsive MerR homologue in Escherichia coli. Outten CE, Outten FW, O'Halloran TV, J Biol Chem 1999 274 37517 37524 (Pubitemid 30026804)
25. ZccR- a MerR-like regulator from Bordetella pertussis, which responds to zinc, cadmium and cobalt. Kidd SP, Brown NL, Biochem Biophys Res Comm 2003 302 697 702 (Pubitemid 36294029)
26. Bacterial sensing of and resistance to gold salts. Checa SK, Espariz M, Perez Audero ME, Botta PE, Spinelli SV, Soncini FC, Mol Microbiol 2007 63 1307 1318
27. Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR. Changela A, Chen K, Xue Y, Holschen J, Outten CE, O'Halloran TV, Mondragon A, Science 2003 301 1383 1387 (Pubitemid 37075815)
28. The MerR Metalloregulatory Protein Binds Mercuric Ion as a Tricoordinate, Metal-Bridged Dimer. Helmann JD, Ballard BT, Walsh CT, Science 1990 248 946 948
29. Mutagenesis of the cysteines in the metalloregulatory protein MerR indicates that a metal-bridged dimer activates transcription. Shewchuk LM, Verdine GL, Nash H, Walsh CT, Biochemistry 1989 28 6140 6145 (Pubitemid 19202000)
30. Sambrook J, Fritsch EF, Maniatis T, Molecular cloning: A laboratory manual Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York 1989
31. Gibson T, Studies on the Eppstein-Barr virus genome University of Cambridge, Cambridge, U.K 1984
32. Efficient oligonucleotide-directed construction of mutations in expression vectors by the gapped duplex DNA method using alternating selectable markers. Stanssens P, Opsomer C, McKeown YM, Kramer W, Zabeau M, Fritz HJ, Nucleic Acid Res 1989 17 4441 4454 (Pubitemid 19165019)
33. Mutations affecting translational coupling between the rep genes of an IncB miniplasmid. Praszkier J, Wilson IW, Pittard AJ, J Bacteriol 1992 174 2376 2383
34. New pUC-derived cloning vectors with different selectable markers and DNA replication origins. Vieira J, Messing J, Gene 1991 100 189 194
35. Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Bradford MM, Anal Biochem 1976 72 248 254
36. Construction and characterization of a mercury-independent MerR activator (MerRAC): transcriptional activation in the absence of Hg(II) is accompanied by DNA distortion. Parkhill J, Ansari AZ, Wright JG, Brown NL, O'Halloran TV, EMBO J 1993 12 413 421 (Pubitemid 23073687)
37. Protein-DNA interactions. Savery N, Belyaeva T, Busby S, Essential Techniques: Gene Transcription John Wiley and sons, Chichester, Docherty K, 1996 1 33
38. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR, Gene 1989 77 51 59 (Pubitemid 19125653)
39. Miller J, Experiments in Molecular Genetics Cold spring Harbor Laboratory Press, Cold Spring Harbor, New York 1972
40. The MerR heavy metal receptor mediates positive activation in a topologically novel transcription complex. OHalloran TV, Frantz B, Shin MK, Ralston DM, Wright JG, Cell 1989 56 119 129
41. Site-specific insertion and deletion mutants in the mer promoter-operator region of Tn501; the nineteen base-pair spacer is essential for normal induction of the promoter by MerR. Parkhill J, Brown NL, Nucleic Acid Res 1990 18 5157 5162
42. Analysis of Escherichia coli promoter sequences. Harley CB, Reynolds RP, Nucleic Acid Res 1987 15 2343 2361
43. DNA-bend modulation in a repressor-to-activator switching mechanism. Ansari AZ, Bradner JE, O'Halloran TV, Nature 1995 374 371 375
44. Allosteric underwinding of DNA is a critical step in positive control of transcription by Hg-MerR. Ansari AZ, Chael ML, O'Halloran TV, Nature 1995 355 87 89
45. Genetic analysis of transcriptional activation and repression in the Tn21 mer operon. Ross W, Park S-J, Summers AO, J Bacteriol 1989 171 4009 4018 (Pubitemid 19174176)
46. Transcriptional switching by the MerR protein: activation and repression mutants implicate distinct DNA and mercury (II) binding domains. Shewchuk LM, Helmann JD, Ross W, Park S-J, Summers AO, Walsh CT, Biochemistry 1989 28 2340 2344 (Pubitemid 19084463)
47. ClustalW and ClustalX version 2. Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, Thompson JD, Gibson TJ, Higgins DG, Bioinformatics 2007 23 2947 2948
48. A design for life: prokaryotic metal-binding MerR family regulators. Hobman JL, Wilkie J, Brown NL, Biometals 2005 18 429 436 (Pubitemid 41298026)
49. Role of cysteinyl residues in sensing Pb(II), Cd(II), and Zn(II) by the plasmid pI258 CadC repressor. Sun Y, Wong MD, Rosen BP, J Biol Chem 2001 276 14955 14960
50. Ratiometric pulsed alkylation mass spectrometry as a probe of thiolate reactivity in different metalloderivatives of Staphylococcus aureus pI258 CadC. Apuy JL, Busenlehner LS, Russell DH, Giedroc DP, Biochemistry 2004 43 3824 3834 (Pubitemid 38437048)
51. Elucidation of primary (3N) and vestigial (5) heavy metal-binding sites in Staphylococcus aureus pI258 CadC: evolutionary implications for metal ion selectivity of ArsR/SmtB metal sensor proteins. Busenlehner LS, Weng T-C, Penner-Hahn JE, Giedroc DP, J Mol Biol 2002 319 685 701 (Pubitemid 34729443)
52. Reexamination of lead(II) coordination preferences in sulphur-rich sites: implications for a critical mechanism of lead poisoning. Magyar JS, Weng T-C, Stern CM, Dye DF, Rous BW, Payne JC, Bridgewater BM, Mijovilovich A, Parkin G, Zaleski JM, Penner-Hahn JE, Godwin HA, J Am Chem Soc 2005 127 9495 9505 (Pubitemid 40934761)
53. Characterization of the first N2S(alkylthiolate) lead compound: A model for three-coordinate lead in biological systems. Anderson RJ, diTargiani RC, Hancock RD, Stern CL, Goldberg DP, Godwin HA, Inorg Chem 2006 45 6574 6576
54. The SmtB/ArsR family of metalloregulatory transcriptional repressors: structural insights into prokaryotic metal resistance. Busenlehner LS, Pennella MA, Giedroc DP, FEMS Microbiol Rev 2003 27 131 143 (Pubitemid 36694652)
55. Comparative genomics of regulation of heavy metal resistance in eubacteria. Permina EA, Kazakov AE, Kalinina OV, Gelfand MS, BMC Microbiol 2006 6 49
56. Whole cell and protein-based biosensors for the detection of bioavailable heavy metals in environmental samples. Corbisier P, van der Lelie D, Borremans B, Provoost A, de Lorenzo V, Brown NL, Lloyd JR, Hobman JL, Csoregi E, Johansson G, Mattiasson B, Anal Chim Acta 1999 387 235 244 (Pubitemid 29172948)
57. The functional analysis of directed amino-acid alterations in ZntR from Escherichia coli. Khan S, Brocklehurst KR, Jones GW, Morby AP, Biochem Biophys Res Commun 2002 299 438 445 (Pubitemid 35365648)