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Volumn 13, Issue 1, 2012, Pages

Simulating gene-gene and gene-environment interactions in complex diseases: Gene-Environment iNteraction Simulator 2

Author keywords

Complex disease; Computer simulation; Epistasis; Gene environment interaction; Genetic; Genetics; Genome wide association study; Genomics; Linkage disequilibrium; Population; SimuPOP

Indexed keywords

COMPLEX DISEASE; EPISTASIS; GENE-ENVIRONMENT INTERACTION; GENETIC; GENETICS; GENOME-WIDE ASSOCIATION STUDIES; GENOMICS; LINKAGE DISEQUILIBRIUM; POPULATION; SIMUPOP;

EID: 84862231203     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-13-132     Document Type: Article
Times cited : (12)

References (23)
  • 1
    • 34548340684 scopus 로고    scopus 로고
    • New models of collaboration in genome-wide association studies: the Genetic Association Information Network
    • 10.1038/ng2127, 17728769, Group TGCR
    • Group TGCR New models of collaboration in genome-wide association studies: the Genetic Association Information Network. Nat Genet 2007, 39(9):1045-51. [http://view.ncbi.nlm.nih.gov/pubmed/17728769], 10.1038/ng2127, 17728769, Group TGCR.
    • (2007) Nat Genet , vol.39 , Issue.9 , pp. 1045-1051
  • 2
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • 10.1038/ng1071, 12524541
    • Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003, 33:177-182. 10.1038/ng1071, 12524541.
    • (2003) Nat Genet , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 3
    • 0028857007 scopus 로고
    • Polygenic disease: methods for mapping complex disease traits
    • 10.1016/S0168-9525(00)89163-5, 8533170
    • Weeks DE, Lathrop GM. Polygenic disease: methods for mapping complex disease traits. Trends Genet 1995, 11(12):513-9. [http://view.ncbi.nlm.nih.gov/pubmed/8533170], 10.1016/S0168-9525(00)89163-5, 8533170.
    • (1995) Trends Genet , vol.11 , Issue.12 , pp. 513-519
    • Weeks, D.E.1    Lathrop, G.M.2
  • 5
    • 0026675062 scopus 로고
    • Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
    • 10.1038/359641a0, 1328889
    • Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard JM, Bara L, Ricard S. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992, 359:641-644. 10.1038/359641a0, 1328889.
    • (1992) Nature , vol.359 , pp. 641-644
    • Cambien, F.1    Poirier, O.2    Lecerf, L.3    Evans, A.4    Cambou, J.P.5    Arveiler, D.6    Luc, G.7    Bard, J.M.8    Bara, L.9    Ricard, S.10
  • 6
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • 10.1161/01.CIR.93.1.7, 8616944
    • Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, Rosenberg IH, Selhub J, Rozen R. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 1996, 93:7-9. 10.1161/01.CIR.93.1.7, 8616944.
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Bostom, A.G.2    Williams, R.R.3    Ellison, R.C.4    Eckfeldt, J.H.5    Rosenberg, I.H.6    Selhub, J.7    Rozen, R.8
  • 7
    • 15944383403 scopus 로고    scopus 로고
    • Gene-environment interactions in human diseases
    • Hunter DJ. Gene-environment interactions in human diseases. Nat Rev Genet 2005, 6(4):287-98. [http://view.ncbi.nlm.nih.gov/pubmed/15803198].
    • (2005) Nat Rev Genet , vol.6 , Issue.4 , pp. 287-298
    • Hunter, D.J.1
  • 8
    • 33847059518 scopus 로고    scopus 로고
    • Detection of gene x gene interactions in genome-wide association studies of human population data
    • 10.1159/000099179, 17283436
    • Musani SK, Shriner D, Liu N, Feng R, Coffey CS, Yi N, Tiwari HK, Allison DB. Detection of gene x gene interactions in genome-wide association studies of human population data. Hum Hered 2007, 63:67-84. 10.1159/000099179, 17283436.
    • (2007) Hum Hered , vol.63 , pp. 67-84
    • Musani, S.K.1    Shriner, D.2    Liu, N.3    Feng, R.4    Coffey, C.S.5    Yi, N.6    Tiwari, H.K.7    Allison, D.B.8
  • 9
    • 0037057235 scopus 로고    scopus 로고
    • Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure
    • 10.1056/NEJMoa020803, 12374873
    • Small KM, Wagoner LE, Levin AM, Kardia SL, Liggett SB. Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure. N Engl J Med 2002, 347:1135-1142. 10.1056/NEJMoa020803, 12374873.
    • (2002) N Engl J Med , vol.347 , pp. 1135-1142
    • Small, K.M.1    Wagoner, L.E.2    Levin, A.M.3    Kardia, S.L.4    Liggett, S.B.5
  • 10
    • 0036138963 scopus 로고    scopus 로고
    • Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma
    • 10.1086/338242, 384891, 11709756
    • Howard TD, Koppelman GH, Xu J, Zheng SL, Postma DS, Meyers DA, Bleecker ER. Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma. Am J Hum Genet 2002, 70:230-236. 10.1086/338242, 384891, 11709756.
    • (2002) Am J Hum Genet , vol.70 , pp. 230-236
    • Howard, T.D.1    Koppelman, G.H.2    Xu, J.3    Zheng, S.L.4    Postma, D.S.5    Meyers, D.A.6    Bleecker, E.R.7
  • 13
    • 78650150425 scopus 로고    scopus 로고
    • You've gotta be lucky: Coverage and the elusive gene-gene interaction
    • 10.1111/j.1469-1809.2010.00615.x, 3005128, 20977438
    • Reimherr M, Nicolae DL. You've gotta be lucky: Coverage and the elusive gene-gene interaction. Ann Hum Genet 2011, 75:105-111. 10.1111/j.1469-1809.2010.00615.x, 3005128, 20977438.
    • (2011) Ann Hum Genet , vol.75 , pp. 105-111
    • Reimherr, M.1    Nicolae, D.L.2
  • 14
    • 77349092838 scopus 로고    scopus 로고
    • A novel approach to simulate gene-environment interactions in complex diseases
    • 10.1186/1471-2105-11-8, 2824681, 20051127
    • Amato R, Pinelli M, D'Andrea D, Miele G, Nicodemi M, Raiconi G, Cocozza S. A novel approach to simulate gene-environment interactions in complex diseases. BMC Bioinformatics 2010, 11:8. 10.1186/1471-2105-11-8, 2824681, 20051127.
    • (2010) BMC Bioinformatics , vol.11 , pp. 8
    • Amato, R.1    Pinelli, M.2    D'Andrea, D.3    Miele, G.4    Nicodemi, M.5    Raiconi, G.6    Cocozza, S.7
  • 15
    • 84872177705 scopus 로고    scopus 로고
    • North Shore LIJ Research Institute List of Genetic Analysis Software page
    • North Shore LIJ Research Institute List of Genetic Analysis Software page. [http://www.nslij-genetics.org/soft/].
  • 16
    • 78751680980 scopus 로고    scopus 로고
    • Simulating gene-environment interactions in complex human diseases
    • 10.1186/gm142, 2873799, 20346093
    • Peng B. Simulating gene-environment interactions in complex human diseases. Genome Med 2010, 2:21. 10.1186/gm142, 2873799, 20346093.
    • (2010) Genome Med , vol.2 , pp. 21
    • Peng, B.1
  • 17
    • 2142705388 scopus 로고    scopus 로고
    • STUDENTJAMA. The challenges of whole-genome approaches to common diseases
    • 10.1001/jama.291.13.1642, 15069055
    • Moore JH, Ritchie MD. STUDENTJAMA. The challenges of whole-genome approaches to common diseases. JAMA 2004, 291:1642-1643. 10.1001/jama.291.13.1642, 15069055.
    • (2004) JAMA , vol.291 , pp. 1642-1643
    • Moore, J.H.1    Ritchie, M.D.2
  • 18
    • 34047228125 scopus 로고    scopus 로고
    • Forward-Time Simulations of Human Populations with Complex Diseases
    • 1829403, 17381243
    • Peng B, Amos CI, Kimmel M. Forward-Time Simulations of Human Populations with Complex Diseases. PLoS Genetics 2007, 3(3):e47+. [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1829403&rendertype=abstract], 1829403, 17381243.
    • (2007) PLoS Genetics , vol.3 , Issue.3
    • Peng, B.1    Amos, C.I.2    Kimmel, M.3
  • 19
    • 77956480238 scopus 로고    scopus 로고
    • Forward-time simulation of realistic samples for genome-wide association studies
    • 10.1186/1471-2105-11-442, 2939614, 20809983
    • Peng B, Amos CI. Forward-time simulation of realistic samples for genome-wide association studies. BMC Bioinformatics 2010, 11:442. 10.1186/1471-2105-11-442, 2939614, 20809983.
    • (2010) BMC Bioinformatics , vol.11 , pp. 442
    • Peng, B.1    Amos, C.I.2
  • 20
    • 84872182478 scopus 로고    scopus 로고
    • HapMap project home page
    • HapMap project home page. [http://hapmap.ncbi.nlm.nih.gov/].
  • 21
    • 84872194469 scopus 로고    scopus 로고
    • Gene-Environment iNteraction Simulator 2 Download Page
    • Gene-Environment iNteraction Simulator 2 Download Page. [http://sourceforge.net/projects/gensim].
  • 22
    • 79961193174 scopus 로고    scopus 로고
    • HAPGEN2: simulation of multiple disease SNPs
    • 10.1093/bioinformatics/btr341, 3150040, 21653516
    • Su Z, Marchini J, Donnelly P. HAPGEN2: simulation of multiple disease SNPs. Bioinformatics 2011, 27:2304-2305. 10.1093/bioinformatics/btr341, 3150040, 21653516.
    • (2011) Bioinformatics , vol.27 , pp. 2304-2305
    • Su, Z.1    Marchini, J.2    Donnelly, P.3
  • 23
    • 41049102190 scopus 로고    scopus 로고
    • Generating samples for association studies based on HapMap data
    • 10.1186/1471-2105-9-44, 2375120, 18218094
    • Li J, Chen Y. Generating samples for association studies based on HapMap data. BMC Bioinformatics 2008, 9:44. 10.1186/1471-2105-9-44, 2375120, 18218094.
    • (2008) BMC Bioinformatics , vol.9 , pp. 44
    • Li, J.1    Chen, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.