Forward-time simulations of human populations with complex diseases

PLoS Genetics

Volumn 3, Issue 3, 2007, Pages 0407-0420

  Peng, Bo ^a   Amos, Christopher I ^a   Kimmel, Marek ^b,c  

^a UNIVERSITY OF TEXAS   (United States)

^b Rice University   (United States)

^c SILESIAN UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DISEASE PREDISPOSITION; EVOLUTIONARY HOMOLOGY; GENE FREQUENCY; GENE INTERACTION; GENE LOCUS; GENE MAPPING; GENETIC ANALYSIS; GENOTYPE; HUMAN; MUTANT; POPULATION GENETICS; QUANTITATIVE TRAIT; SIMULATION; ALGORITHM; BIOLOGICAL MODEL; CASE CONTROL STUDY; CHROMOSOME MAP; COMPUTER SIMULATION; DIABETES MELLITUS; EVOLUTION; GENE LINKAGE DISEQUILIBRIUM; GENERAL ASPECTS OF DISEASE; GENETIC DRIFT; GENETIC MARKER; GENETIC RECOMBINATION; GENETIC SELECTION; GENETICS; HUMAN CHROMOSOME; HYPERTENSION; MIGRATION; NEOPLASM; ONSET AGE; PATHOLOGY; PEDIGREE; POINT MUTATION; POISSON DISTRIBUTION; PROPORTIONAL HAZARDS MODEL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL; TIME;

MICROSATELLITE DNA;

AGE OF ONSET; ALGORITHMS; ALLELES; CASE-CONTROL STUDIES; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN; COMPUTER SIMULATION; DEMOGRAPHY; DIABETES MELLITUS; DISEASE; DISEASE SUSCEPTIBILITY; EMIGRATION AND IMMIGRATION; EVOLUTION; GENE FREQUENCY; GENETIC DRIFT; GENETIC MARKERS; GENETICS, POPULATION; GENOTYPE; HUMANS; HYPERTENSION; LINKAGE DISEQUILIBRIUM; LOGISTIC MODELS; MICROSATELLITE REPEATS; MODELS, GENETIC; NEOPLASMS; PEDIGREE; POINT MUTATION; POISSON DISTRIBUTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; QUANTITATIVE TRAIT LOCI; RECOMBINATION, GENETIC; SELECTION (GENETICS); TIME;

EID: 34047228125     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0030047     Document Type: Article

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