Attenuation of prostaglandin E 2 elimination across the mouse blood-brain barrier in lipopolysaccharide-induced inflammation and additive inhibitory effect of cefmetazole

Fluids and Barriers of the CNS

Volumn 8, Issue 1, 2011, Pages

  Akanuma, Shin Ichi ^a   Uchida, Yasuo ^b   Ohtsuki, Sumio ^b   Tachikawa, Masanori ^b   Terasaki, Tetsuya ^b   Hosoya, Ken Ichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

Blood brain barrier; Inflammation; Lipopolysaccharide; MRP4; Multidrug resistance associated protein; Oat3; Oatp1a4; PGE2; Prostaglandin; Transporter

Indexed keywords

CARRIER PROTEIN; CEFAZOLIN; CEFMETAZOLE; LIPOPOLYSACCHARIDE; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER 3; ORGANIC ANION TRANSPORTING POLYPEPTIDE 1A4; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; BRAIN EFFLUX INDEX; CONTROLLED STUDY; DRUG EFFECT; EFFUSION; INFLAMMATION; INHIBITION KINETICS; LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; TANDEM MASS SPECTROMETRY;

EID: 84862206258     PISSN: None     EISSN: 20458118     Source Type: Journal    
DOI: 10.1186/2045-8118-8-24     Document Type: Article

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