Association of statin use with risk and outcome of acute kidney injury in Community-acquired pneumonia

Clinical Journal of the American Society of Nephrology

Volumn 7, Issue 6, 2012, Pages 895-905

  Murugan, Raghavan ^a   Weissfeld, Lisa ^a,b   Yende, Sachin ^a   Singbartl, Kai ^a   Angus, Derek C ^a   Kellum, John A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ACUTE KIDNEY FAILURE; ADULT; AGE; AGED; ARTICLE; ARTIFICIAL VENTILATION; CARDIOVASCULAR DISEASE; COHORT ANALYSIS; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DEATH; DISEASE SEVERITY; FEMALE; HEALTH INSURANCE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NURSING HOME; PROPENSITY SCORE; PROSPECTIVE STUDY;

ACUTE KIDNEY INJURY; AGED; AGED, 80 AND OVER; CHI-SQUARE DISTRIBUTION; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HOSPITALIZATION; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PNEUMONIA; PROPENSITY SCORE; PROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES;

EID: 84862189046     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.07100711     Document Type: Article

References (34)

1. Murugan R, Karajala-Subramanyam V, Lee M, Yende S, Kong L, Carter M, Angus DC, Kellum JA; Genetic and Inflammatory Markers of Sepsis (GenIMS) Investigators: Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int 77: 527-535, 2010
2. Murugan R, Kellum JA: Acute kidney injury: What's the prognosis? Nat Rev Nephrol 7: 209-217, 2011
3. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C; Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators: Acute renal failure in critically ill patients: A multinational, multicenter study. JAMA 294: 813-818, 2005
4. Bagshaw SM, Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten HM, Ronco C, Kellum JA; Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators: Septic acute kidney injury in critically ill patients: Clinical characteristics and outcomes. Clin J Am Soc Nephrol 2: 431-439, 2007
5. Schrier RW, Wang W: Acute renal failure and sepsis. N Engl J Med 351: 159-169, 2004
6. Chen YC, Jenq CC, Tian YC, Chang MY, Lin CY, Chang CC, Lin HC, Fang JT, Yang CW, Lin SM: Rifle classification for predicting in-hospital mortality in critically ill sepsis patients. Shock 31: 139-145, 2009
7. James MT, Ghali WA, Knudtson ML, Ravani P, Tonelli M, Faris P, Pannu N, Manns BJ, Klarenbach SW, Hemmelgarn BR; Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) Investigators: Associations between acute kidney injury and cardiovascular and renal outcomes after coronary angiography. Circulation 123: 409-416, 2011
8. Hobson CE, Yavas S, Segal MS, Schold JD, Tribble CG, Layon AJ, Bihorac A: Acute kidney injury is associated with increased longterm mortality after cardiothoracic surgery. Circulation 119: 2444-2453, 2009
9. Parikh CR, Coca SG, Wang Y, Masoudi FA, Krumholz HM: Longterm prognosis of acute kidney injury after acute myocardial infarction. Arch Intern Med 168: 987-995, 2008
10. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet 344: 1383-1389, 1994
11. Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, McKillop JH, Packard CJ; West of Scotland Coronary Prevention Study Group: Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 333: 1301-1307, 1995
12. Albert MA, Danielson E, Rifai N, Ridker PM; PRINCE Investigators: Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): A randomized trial and cohort study. JAMA 286: 64-70, 2001
13. Novack V, Eisinger M, Frenkel A, Terblanche M, Adhikari NK, Douvdevani A, Amichay D, Almog Y: The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: A randomized double-blind placebo controlled clinical trial. Intensive Care Med 35: 1255-1260, 2009
14. Undas A, Brummel KE, Musial J, Mann KG, Szczeklik A: Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation. Circulation 103: 2248-2253, 2001
15. O'Neal HR Jr, Koyama T, Koehler EA, Siew E, Curtis BR, Fremont RD, May AK, Bernard GR, Ware LB: Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/ acute respiratory distress syndrome. Crit Care Med 39: 1343-1350, 2011
16. Majumdar SR, McAlister FA, Eurich DT, Padwal RS, Marrie TJ: Statins and outcomes in patients admitted to hospital with community acquired pneumonia: Population based prospective cohort study. BMJ 333: 999, 2006
17. Yende S, Milbrandt EB, Kellum JA, Kong L, Delude RL, Weissfeld LA, Angus DC: Understanding the potential role of statins in pneumonia and sepsis. Crit Care Med 39: 1871-1878, 2011
18. Yasuda H, Yuen PS, Hu X, Zhou H, Star RA: Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects. Kidney Int 69: 1535-1542, 2006
19. Kellum JA, Kong L, Fink MP, Weissfeld LA, Yealy DM, Pinsky MR, Fine J, Krichevsky A, Delude RL, Angus DC; GenIMS Investigators: Understanding the inflammatory cytokine response in pneumonia and sepsis: Results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study. Arch Intern Med 167: 1655-1663, 2007
20. Fine MJ, Auble TE, Yealy DM, Hanusa BH, Weissfeld LA, Singer DE, Coley CM, Marrie TJ, Kapoor WN: A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 336: 243-250, 1997
21. Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40: 373-383, 1987
22. Knaus WA, Wagner DP, Draper EA, Zimmerman JE, Bergner M, Bastos PG, Sirio CA, Murphy DJ, Lotring T, Damiano A, et al: The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest 100: 1619-1636, 1991
23. Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G; SCCM/ESICM/ACCP/ ATS/SIS: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 31: 1250-1256, 2003
24. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG: The SOFA (Sepsisrelated Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 22: 707-710, 1996
25. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P; Acute Dialysis Quality Initiative workgroup: Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: The Second International Consensus Conference of theAcute DialysisQuality Initiative (ADQI) Group. Crit Care 8: R204-R212, 2004
26. National Kidney Foundation: K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Am J Kidney Dis 39[Suppl 1]: S1-S266, 2002
27. Hoste EA, Clermont G, Kersten A, Venkataraman R, Angus DC, De Bacquer D, Kellum JA: RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: A cohort analysis. Crit Care 10: R73, 2006
28. Rich-Edwards JW, Corsano KA, Stampfer MJ: Test of the National Death Index and Equifax Nationwide Death Search. Am J Epidemiol 140: 1016-1019, 1994
29. Liang KY, Zeger SL: Longitudinal data analysis using generalized linear models. Biometrika 73: 13-22, 1986
30. Braitman LE, Rosenbaum PR: Rare outcomes, common treatments: Analytic strategies using propensity scores. Ann Intern Med 137: 693-695, 2002
31. Brookhart MA, Patrick AR, Dormuth C, Avorn J, Shrank W, Cadarette SM, Solomon DH: Adherence to lipid-lowering therapy and the use of preventive health services: An investigation of the healthy user effect. Am J Epidemiol 166: 348-354, 2007
32. Dublin S, Jackson ML, Nelson JC, Weiss NS, Larson EB, Jackson LA: Statin use and risk of community acquired pneumonia in older people: Population based case-control study. BMJ 338: b2137, 2009
33. Lopes JA, Fernandes P, Jorge S, Resina C, Santos C, Pereira A, Neves J, Antunes F, Gomes da Costa A: Long-term risk of mortality after acute kidney injury in patients with sepsis: A contemporary analysis. BMC Nephrol 11: 9, 2010
34. Molnar AO, Coca SG, Devereaux PJ, Jain AK, Kitchlu A, Luo J, Parikh CR, Paterson JM, Siddiqui N, Wald R, Walsh M, Garg AX: Statin use associates with a lower incidence of acute kidney injury after major elective surgery. J Am Soc Nephrol 22: 939-946, 2011