Conversion of a dodecahedral protein capsid into pentamers via minimal point mutations

Biochemistry

Volumn 51, Issue 23, 2012, Pages 4704-4712

  Chen, Hsiao Nung ^a   Woycechowsky, Kenneth J ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; AQUIFEX AEOLICUS; BIOCATALYSIS; BIOPHYSICAL CHARACTERIZATION; INTERACTION SITE; MATERIALS SYNTHESIS; MINIMAL POINTS; NANOSCALE ARCHITECTURES; NON-COVALENT INTERACTION; PENTAMERS; PROTEIN COMPLEXES; PROTEIN FAMILY; QUATERNARY STRUCTURE; SIDE-CHAINS; STRUCTURE-FUNCTION RELATIONSHIP; SUBUNIT INTERFACES; SYNTHASES; TERTIARY STRUCTURES;

AMINO ACIDS; DRUG DELIVERY; HYDROGEN BONDS; PROTEINS; SELF ASSEMBLY;

BIOSYNTHESIS;

AMINO ACID; HYDROGEN; LUMAZINE SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AQUIFEX AEOLICUS; ARTICLE; BINDING SITE; BIOCATALYSIS; DODECAHEDRAL PROTEIN CAPSID; DRUG DELIVERY SYSTEM; ENZYME ANALYSIS; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; PENTAMER PROTEIN CAPSID; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

BACTERIAL PROTEINS; CIRCULAR DICHROISM; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY;

EID: 84862181184     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3003555     Document Type: Article

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