The use of multiplexed MRM for the discovery of biomarkers to differentiate iron-deficiency anemia from anemia of inflammation

Journal of Proteomics

Volumn 75, Issue 12, 2012, Pages 3514-3528

  Domanski, Dominik ^a   Cohen Freue, Gabriela V ^b,c   Sojo, Luis ^d   Kuzyk, Michael A ^a   Ratkay, Leslie ^d   Parker, Carol E ^a   Goldberg, Y Paul ^d   Borchers, Christoph H ^a,e  

^a UNIVERSITY OF VICTORIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c NCE CECR PROOF Centre of Excellence   (Canada)

^d Xenon Pharmaceuticals Inc   (Canada)

^e UNIVERSITY OF VICTORIA   (Canada)

Author keywords

Biomarkers; Inflammation; Inflammation plus iron deficiency Anemia; Iron deficiency anemia; Multiple reaction monitoring; Multiplexed quantitation

Indexed keywords

APOLIPOPROTEIN A4; BIOLOGICAL MARKER; CATALASE; CD71 ANTIGEN; CERULOPLASMIN; HAPTOGLOBIN; HEMOGLOBIN; HEMOPEXIN; LACTOFERRIN; NEUTROPHIL COLLAGENASE; TRANSFERRIN;

ACIDIFICATION; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL MONITORING; BLOOD SAMPLING; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; DISEASE ASSOCIATION; ERYTHROPOIESIS; EXPERIMENTAL MODEL; FEMALE; GENETIC REGULATION; GENETIC VARIABILITY; HOMEOSTASIS; INFLAMMATION; IRON DEFICIENCY ANEMIA; IRON METABOLISM; IRON TRANSPORT; MACROPHAGE; MASS SPECTROMETRY; MOUSE; MULTIPLE REACTION MONITORING; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

ANEMIA; ANEMIA, IRON-DEFICIENCY; ANIMALS; BIOLOGICAL MARKERS; BLOOD PROTEINS; DIAGNOSIS, DIFFERENTIAL; FEMALE; INFLAMMATION; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; PEPTIDE MAPPING; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84862177872     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2011.11.022     Document Type: Article

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