Urinary bladder relaxation through activation of opioid μ-receptors induced by loperamide is increased in diabetic rats

Experimental and Clinical Endocrinology and Diabetes

Volumn 120, Issue 6, 2012, Pages 323-328

  Lee, L M ^a   Lin, C S ^b   Chung, H H ^c   Lin, K C ^b,d   Cheng, J T ^b,c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

ATP sensitive K + channels; isometric tension; loperamide; opioid receptors; overactive bladder

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ADENYLATE CYCLASE ACTIVATOR; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYPRODIME; FORSKOLIN; GLIBENCLAMIDE; ISOBUTYLMETHYLXANTHINE; LOPERAMIDE; MU OPIATE RECEPTOR; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NALOXONAZINE; NALOXONE; PHOSPHODIESTERASE INHIBITOR; POTASSIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER MUSCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DETRUSOR MUSCLE; DIABETES MELLITUS; DRUG EFFECT; DRUG TARGETING; MALE; MUSCLE RELAXATION; MUSCLE TONE; NONHUMAN; OVERACTIVE BLADDER; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

ANIMALS; ANTIDIARRHEALS; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; GLYBURIDE; HYPOGLYCEMIC AGENTS; LOPERAMIDE; MALE; MUSCLE RELAXATION; MUSCLE, SMOOTH; NALOXONE; NARCOTIC ANTAGONISTS; ORGAN CULTURE TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, OPIOID, MU; STREPTOZOCIN; URINARY BLADDER;

EID: 84862167479     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0031-1295473     Document Type: Article

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