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Volumn 28, Issue 3, 2012, Pages 780-787

Limiting cell aggregation during mesenchymal stem cell expansion on microcarriers

Author keywords

Aggregation; Mesenchymal stem cells; Microcarriers

Indexed keywords

AGITATION RATES; CELL AGGREGATION; CELL DENSITY; CELL NUMBER; CELL SOURCES; CLINICAL USE; CULTURE PARAMETERS; LIMITING STEP; MESENCHYMAL STEM CELL; MICROCARRIERS; REGENERATIVE MEDICINE; SPINNER FLASKS; STATIC CULTURE; THERAPEUTIC POTENTIALS;

EID: 84862160094     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1527     Document Type: Article
Times cited : (67)

References (39)
  • 1
    • 36248932643 scopus 로고    scopus 로고
    • Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing
    • Chamberlain G, Fox J, Ashton B, Middleton J. Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing. Stem Cells. 2007; 25: 2739-2749.
    • (2007) Stem Cells. , vol.25 , pp. 2739-2749
    • Chamberlain, G.1    Fox, J.2    Ashton, B.3    Middleton, J.4
  • 2
    • 34848863384 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
    • Caplan AI. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol. 2007; 213: 341-347.
    • (2007) J Cell Physiol. , vol.213 , pp. 341-347
    • Caplan, A.I.1
  • 3
    • 58449135981 scopus 로고    scopus 로고
    • Why are MSCs therapeutic? New data: new insight
    • Caplan AI. Why are MSCs therapeutic? New data: new insight. J Pathol. 2009; 217: 318-324.
    • (2009) J Pathol. , vol.217 , pp. 318-324
    • Caplan, A.I.1
  • 4
    • 0026437233 scopus 로고
    • Formation of bridges and large cellular clumps in CHO-cell microcarrier cultures: effects of agitation, dimethyl sulfoxide and calf serum
    • Borys MC, Papoutsakis ET. Formation of bridges and large cellular clumps in CHO-cell microcarrier cultures: effects of agitation, dimethyl sulfoxide and calf serum. Cytotechnology. 1992; 8: 237-248.
    • (1992) Cytotechnology. , vol.8 , pp. 237-248
    • Borys, M.C.1    Papoutsakis, E.T.2
  • 8
    • 60549096066 scopus 로고    scopus 로고
    • Ear mesenchymal stem cells: an efficient adult multipotent cell population fit for rapid and scalable expansion
    • Sart S, Schneider YJ, Agathos SN. Ear mesenchymal stem cells: an efficient adult multipotent cell population fit for rapid and scalable expansion. J Biotechnol. 2009; 139: 291-299.
    • (2009) J Biotechnol. , vol.139 , pp. 291-299
    • Sart, S.1    Schneider, Y.J.2    Agathos, S.N.3
  • 9
    • 77957329646 scopus 로고    scopus 로고
    • Influence of culture parameters on ear mesenchymal stem cells expanded on microcarriers
    • Sart S, Schneider YJ, Agathos SN. Influence of culture parameters on ear mesenchymal stem cells expanded on microcarriers. J Biotechnol. 2010; 150: 149-160.
    • (2010) J Biotechnol. , vol.150 , pp. 149-160
    • Sart, S.1    Schneider, Y.J.2    Agathos, S.N.3
  • 10
    • 80051672261 scopus 로고    scopus 로고
    • Expansion and preservation of multipotentiality of rabbit bone-marrow derived mesenchymal stem cells in dextran-based microcarrier spin culture
    • Boo L, Selvaratnam L, Tai CC, Ahmad TS, Kamarul T. Expansion and preservation of multipotentiality of rabbit bone-marrow derived mesenchymal stem cells in dextran-based microcarrier spin culture. J Mater Sci: Mater Med. 2011; 22: 1343-1356.
    • (2011) J Mater Sci: Mater Med. , vol.22 , pp. 1343-1356
    • Boo, L.1    Selvaratnam, L.2    Tai, C.C.3    Ahmad, T.S.4    Kamarul, T.5
  • 12
    • 34247141436 scopus 로고    scopus 로고
    • Ex vivo expansion of rat bone marrow mesenchymal stromal cells on microcarrier beads in spin culture
    • Yang Y, Rossi FMV, Putnins EE. Ex vivo expansion of rat bone marrow mesenchymal stromal cells on microcarrier beads in spin culture. Biomaterials. 2007; 28: 3110-3120.
    • (2007) Biomaterials. , vol.28 , pp. 3110-3120
    • Yang, Y.1    Rossi, F.M.V.2    Putnins, E.E.3
  • 13
    • 61549112193 scopus 로고    scopus 로고
    • 3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells
    • Wang W, Itaka K, Ohba S, Nishiyama N, Chung UI, Yamasaki Y, Kataoka K. 3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cells. Biomaterials. 2009; 30: 2705-2715.
    • (2009) Biomaterials. , vol.30 , pp. 2705-2715
    • Wang, W.1    Itaka, K.2    Ohba, S.3    Nishiyama, N.4    Chung, U.I.5    Yamasaki, Y.6    Kataoka, K.7
  • 15
    • 68549118666 scopus 로고    scopus 로고
    • The use of injectable spherically symmetric cell aggregates self-assembled in a thermo-responsive hydrogel for enhanced cell transplantation
    • Lee WY, Chang YH, Yeh YC, Chen CH, Lin KM, Huang CC, Chang Y, Sung HW. The use of injectable spherically symmetric cell aggregates self-assembled in a thermo-responsive hydrogel for enhanced cell transplantation. Biomaterials. 2009; 30: 5505-5513.
    • (2009) Biomaterials. , vol.30 , pp. 5505-5513
    • Lee, W.Y.1    Chang, Y.H.2    Yeh, Y.C.3    Chen, C.H.4    Lin, K.M.5    Huang, C.C.6    Chang, Y.7    Sung, H.W.8
  • 16
    • 65249111036 scopus 로고    scopus 로고
    • Spherically symmetric mesenchymal stromal cell bodies inherent with endogenous extracellular matrices for cellular cardiomyoplasty
    • Wang CC, Chen CH, Hwang SM, Lin WW, Huang CH, Lee WY, Chang Y, Sung HW. Spherically symmetric mesenchymal stromal cell bodies inherent with endogenous extracellular matrices for cellular cardiomyoplasty. Stem Cells. 2009; 27: 724-732.
    • (2009) Stem Cells. , vol.27 , pp. 724-732
    • Wang, C.C.1    Chen, C.H.2    Hwang, S.M.3    Lin, W.W.4    Huang, C.H.5    Lee, W.Y.6    Chang, Y.7    Sung, H.W.8
  • 17
    • 0042668340 scopus 로고    scopus 로고
    • Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion
    • Baksh D, Davies JE, Zandstra PW. Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion. Exp Hematol. 2003; 31: 723-732.
    • (2003) Exp Hematol. , vol.31 , pp. 723-732
    • Baksh, D.1    Davies, J.E.2    Zandstra, P.W.3
  • 18
    • 78650211966 scopus 로고    scopus 로고
    • Scalable expansion of multipotent adult progenitor cells as three-dimensional cell aggregates
    • Subramanian K, Park Y, Verfaillie CM, Hu WS. Scalable expansion of multipotent adult progenitor cells as three-dimensional cell aggregates. Biotechnol Bioeng. 2010; 108: 364-375.
    • (2010) Biotechnol Bioeng. , vol.108 , pp. 364-375
    • Subramanian, K.1    Park, Y.2    Verfaillie, C.M.3    Hu, W.S.4
  • 19
    • 77955000681 scopus 로고    scopus 로고
    • Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential
    • Frith JE, Thomson B, Genever PG. Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential. Tissue Eng Part C. 2010; 16: 735-749.
    • (2010) Tissue Eng Part C. , vol.16 , pp. 735-749
    • Frith, J.E.1    Thomson, B.2    Genever, P.G.3
  • 22
    • 84862159854 scopus 로고    scopus 로고
    • Expansion of murine embryonic stem cells on microcarriers-functional characteristics and scale-up potential
    • Gòdia F, Fussenegger M, editors. The Netherlands: Springer
    • Burg M, Quel G, Ruediger M, Zweigerdt R. Expansion of murine embryonic stem cells on microcarriers-functional characteristics and scale-up potential. In: Gòdia F, Fussenegger M, editors. Animal Cell Technology meets Genomics. The Netherlands: Springer; 2005: 237-240.
    • (2005) Animal Cell Technology meets Genomics , pp. 237-240
    • Burg, M.1    Quel, G.2    Ruediger, M.3    Zweigerdt, R.4
  • 24
    • 76649133306 scopus 로고    scopus 로고
    • Critical fluid shear stress analysis for cell-polymer adhesion
    • Rocha A, Hahn M, Liang H. Critical fluid shear stress analysis for cell-polymer adhesion. J Mater Sci. 2010; 45: 811-817.
    • (2010) J Mater Sci. , vol.45 , pp. 811-817
    • Rocha, A.1    Hahn, M.2    Liang, H.3
  • 25
    • 0034307024 scopus 로고    scopus 로고
    • The effect of fluid shear stress on endothelial cell adhesiveness to polymer surfaces with wettability gradient
    • Lee JH, Lee SJ, Khang G, Lee HB. The effect of fluid shear stress on endothelial cell adhesiveness to polymer surfaces with wettability gradient. J Colloid Interface Sci. 2000; 230: 84-90.
    • (2000) J Colloid Interface Sci. , vol.230 , pp. 84-90
    • Lee, J.H.1    Lee, S.J.2    Khang, G.3    Lee, H.B.4
  • 26
    • 69549118411 scopus 로고    scopus 로고
    • Cell aggregation on agar as an indicator for cell-matrix adhesion: effects of opioids
    • Debruyne D, Mareel M, Vanhoecke B, Bracke M. Cell aggregation on agar as an indicator for cell-matrix adhesion: effects of opioids. In Vitro Cell. Dev Biol Animal. 2009; 45: 473-482.
    • (2009) In Vitro Cell. Dev Biol Animal. , vol.45 , pp. 473-482
    • Debruyne, D.1    Mareel, M.2    Vanhoecke, B.3    Bracke, M.4
  • 27
    • 33748108166 scopus 로고    scopus 로고
    • Application of hanging drop technique for stem cell differentiation and cytotoxicity studies
    • Banerjee M, Bhonde RR. Application of hanging drop technique for stem cell differentiation and cytotoxicity studies. Cytotechnology. 2006; 51: 1-5.
    • (2006) Cytotechnology. , vol.51 , pp. 1-5
    • Banerjee, M.1    Bhonde, R.R.2
  • 28
    • 34948812489 scopus 로고    scopus 로고
    • Wettability of substrata controls cell-substrate and cell-cell adhesions
    • Tzoneva R, Faucheux N, Groth T. Wettability of substrata controls cell-substrate and cell-cell adhesions. Biochim Biophys Acta. 2007; 1770: 1538-1547.
    • (2007) Biochim Biophys Acta. , vol.1770 , pp. 1538-1547
    • Tzoneva, R.1    Faucheux, N.2    Groth, T.3
  • 30
    • 0035836686 scopus 로고    scopus 로고
    • Tissue spreading on implantable substrates is a competitive outcome of cell-cell vs. cell-substratum adhesivity
    • Ryan PL, Foty RA, Kohn J, Steinberg MS. Tissue spreading on implantable substrates is a competitive outcome of cell-cell vs. cell-substratum adhesivity. Proc Natl Acad Sci USA. 2001; 98: 4323-4327.
    • (2001) Proc Natl Acad Sci USA. , vol.98 , pp. 4323-4327
    • Ryan, P.L.1    Foty, R.A.2    Kohn, J.3    Steinberg, M.S.4
  • 31
    • 19944423801 scopus 로고    scopus 로고
    • Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers
    • Burleson KM, Hansen LK, Skubitz APN. Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers. Clin Exp Metastas. 2005; 21: 685-697.
    • (2005) Clin Exp Metastas. , vol.21 , pp. 685-697
    • Burleson, K.M.1    Hansen, L.K.2    Skubitz, A.P.N.3
  • 32
    • 0031908543 scopus 로고    scopus 로고
    • Long-range and selective autoregulation of cell-cell or cell-matrix adhesions by cadherin or integrin ligands
    • Levenberg S, Katz BZ, Yamada KM, Geiger B. Long-range and selective autoregulation of cell-cell or cell-matrix adhesions by cadherin or integrin ligands. J Cell Sci. 1998; 111: 347-357.
    • (1998) J Cell Sci. , vol.111 , pp. 347-357
    • Levenberg, S.1    Katz, B.Z.2    Yamada, K.M.3    Geiger, B.4
  • 33
    • 34247587041 scopus 로고    scopus 로고
    • Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation
    • Kolf CM, Cho E, Tuan RS. Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation. Arthritis Res Ther. 2007; 9: 204.
    • (2007) Arthritis Res Ther. , vol.9 , pp. 204
    • Kolf, C.M.1    Cho, E.2    Tuan, R.S.3
  • 35
    • 66149150611 scopus 로고    scopus 로고
    • Rigidity-dependent cross talk between integrin and cadherin signaling
    • Tsai J, Kam L. Rigidity-dependent cross talk between integrin and cadherin signaling. Biophys J. 2009; 96: L39-L41.
    • (2009) Biophys J. , vol.96
    • Tsai, J.1    Kam, L.2
  • 36
    • 0032858997 scopus 로고    scopus 로고
    • Bead-to-bead-transfer of vero cells in microcarrier culture
    • Wang Y, Ouyang F. Bead-to-bead-transfer of vero cells in microcarrier culture. Bioprocess Eng. 1999; 21: 211-213.
    • (1999) Bioprocess Eng. , vol.21 , pp. 211-213
    • Wang, Y.1    Ouyang, F.2
  • 37
    • 51649141523 scopus 로고
    • Mammalian cell cultivation on serum-coated microcarriers
    • Kim BS, Choi YH, Choi CY, Kim BG. Mammalian cell cultivation on serum-coated microcarriers. Biotechnol Tech. 1992; 6: 347-352.
    • (1992) Biotechnol Tech. , vol.6 , pp. 347-352
    • Kim, B.S.1    Choi, Y.H.2    Choi, C.Y.3    Kim, B.G.4
  • 38
    • 0027314514 scopus 로고
    • Influence of serum proteins on the kinetics of attachment of Vero cells to Cytodex microcarriers
    • Mukhopadhyay A, Mukhopadhyay, SN, Talwar GP. Influence of serum proteins on the kinetics of attachment of Vero cells to Cytodex microcarriers. J Chem Technol Biotechnol. 1993; 56: 369-374.
    • (1993) J Chem Technol Biotechnol. , vol.56 , pp. 369-374
    • Mukhopadhyay, A.1    Mukhopadhyay, S.N.2    Talwar, G.P.3
  • 39
    • 0034688706 scopus 로고    scopus 로고
    • Hydrodynamic effects on animal cells grown in microcarrier cultures
    • Croughan MS, Hamel JF, Wang DIC. Hydrodynamic effects on animal cells grown in microcarrier cultures. Biotechnol Bioeng. 2000; 67: 841-852.
    • (2000) Biotechnol Bioeng. , vol.67 , pp. 841-852
    • Croughan, M.S.1    Hamel, J.F.2    Wang, D.I.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.