Ursodeoxycholic acid improves insulin sensitivity and hepatic steatosis by inducing the excretion of hepatic lipids in high-fat diet-fed KK-A y mice

Metabolism: Clinical and Experimental

Volumn 61, Issue 7, 2012, Pages 944-953

  Tsuchida, Takuma ^a   Shiraishi, Muneshige ^a   Ohta, Tetsuya ^b   Sakai, Kaoru ^a   Ishii, Shinichi ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^b Advanced Medical Research Laboratories   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 3 METHYL GLUTARYL COENZYME A REDUCTASE; BILE ACID; CHOLESTEROL; FATTY ACID; FATTY ACID SYNTHASE; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; PHOSPHOLIPID; STEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; FATTY ACID SYNTHESIS; FATTY LIVER; FECES; GENE EXPRESSION; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPID LIVER LEVEL; LIPID METABOLISM; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION;

ANIMALS; CHOLAGOGUES AND CHOLERETICS; CHOLESTEROL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; ENDOPLASMIC RETICULUM STRESS; FATTY ACIDS; FATTY LIVER; GENE EXPRESSION PROFILING; HYPERGLYCEMIA; HYPERINSULINISM; INSULIN RESISTANCE; LIPID METABOLISM; LIPIDS; MALE; MICE; PHOSPHORYLATION; UP-REGULATION; URSODEOXYCHOLIC ACID;

EID: 84862144999     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.10.023     Document Type: Article

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