Apple leaf extract as a potential candidate for suppressing postprandial elevation of the blood glucose level

Journal of Nutritional Science and Vitaminology

Volumn 58, Issue 1, 2012, Pages 63-67

  Shirosaki, Miyuki ^a   Koyama, Tomoyuki ^a   Yazawa, Kazunaga ^a  

^a TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Anti hyperglycemic effects; Apple leaf extract; Glucose absorption; Malus pumila; Phloridzin

Indexed keywords

ALCOHOL; APPLE LEAF EXTRACT; GLUCOSE; PHLORIZIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APPLE; BIOASSAY; CONTROLLED STUDY; DRUG EFFICACY; DRUG ISOLATION; GLUCOSE ABSORPTION; GLUCOSE BLOOD LEVEL; HEATING; HYPERGLYCEMIA; HYPOGLYCEMIA; MALE; MOUSE; NONHUMAN; NOTE; POSTPRANDIAL STATE; SMALL INTESTINE; SPECTROSCOPY;

ANIMALS; BLOOD GLUCOSE; HYPOGLYCEMIC AGENTS; MALE; MALUS; MICE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHLORHIZIN; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; POSTPRANDIAL PERIOD;

EID: 84862142394     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.58.63     Document Type: Note

References (16)

1. Shirosaki M, Koyama T, Yazawa K. 2008. Anti-hyperglycemic activity of kiwifruit leaf (Actinidia deliciosa) in mice. Biosci Biotechnol Biochem 72: 1099-1102.
2. Shirosaki M, Koyama T, Yazawa K. 2011. Suppressive effects of peach leaf on glucose absorption from the small intestine in mice. Biosci Biotechnol Biochem 76: 89-94.
3. Phillips JP. 1866. A Pembrokeshire Proverb. Notes Queries s3;9: 153.
4. Boyer J, Liu H, Rui L. 2004. Apple phytochemicals and their health benefits. Nutr J 3: 5.
5. Sugiyama H, Akazome Y, Shoji T, Yamaguchi A, Yasue M, Kanda T, Ohtake Y. 2007. Oligomeric procyanidins in apple polyphenol are main active components for inhibition of pancreatic lipase and triglyceride absorption. J Agric Food Chem 55: 4604-4609.
6. 4-induced acute liver damage in mice. J Agric Food Chem 58: 525-531.
7. Iwashina T. 2000. The structure and distribution of the flavonoids in plants. J Plant Res 113: 287-299.
8. Veitch NC, Grayer RJ. 2006. Chalcones, dihydrochalcones, and aurones. In: Flavonoids: Chemistry, Biochemistry and Applications (Andersen MØ, Markham KR eds), p 1033-1071. Taylor & Francis Group, USA.
9. Petersen C. 1835. Analyse des phloridzins. Ann Pharm 15: 178.
10. Stiles PG, Lusk G. 1903. On the action of phlorizin. Am J Physiol 10: 61-79.
11. Chassis H, Joliffe N, Smith H. 1933. The action of phlorizin on the excretion on the excretion of glucose, xylose, sucrose, creatinine and urea by man. J Clin Invest 12: 1083-1089.
12. Sami M, Kanda T, Sunagawa T, Yokota T, Shirasawa T, Shimizu T. 2007. Longevity-extending agents containing fruit polyphenols, and foods, beverages, food additives, pharmaceuticals, and cosmetics containing them. Japan Kokai Tokkyo Koho JKXXAF JP 2007197374 A 20070809, 10 pp.
13. Miyadaka T, Ebata T, Aratsu K. 2003. Stabilized phloretin glycosides for prevention and treatment of diabetes. Japan Kokai Tokkyo Koho JKXXAF JP 2003238417 A 20030827, 10 pp.
14. Ehrenkranz G, Lewis C, Kahn R, Roth J. 2005. Phlorizin: a review. Diabetes Metab Res Rev 21: 31-38.
15. Jagde H, Nguy D, Moller I, Cooney JM, Atkinson RG. 2008. Isolation and characterization of a novel glycosyltransferase that converts phloretin to phloridzin, a potent antioxidant in apple. FEBS J 275: 3804-3918.
16. Petkovsek MM, Stampar F, Veberic R. 2009. Seasonal changes in phenolic compounds in the leaves of scabresistant and susceptible apple cultivars. Can J Plant Sci 89: 745-753.