메뉴 건너뛰기




Volumn 97, Issue 6, 2012, Pages 842-848

Deferasirox for up to 3 years leads to continued improvement of myocardial T2* in patients with β-thalassemia major

(16)  Pennell, Dudley J a   Porter, John B b   Cappellini, Maria Domenica c   Chan, Lee Lee d   El Beshlawy, Amal e   Aydinok, Yesim f   Ibrahim, Hishamshah g   Li, Chi Kong h   Viprakasit, Vip i   Elalfy, Mohsen S j   Kattamis, Antonis k   Smith, Gillian a   Habr, Dany l   Domokos, Gabor l   Roubert, Bernard l   Taher, Ali m  


Author keywords

thalassemia major; Deferasirox; Iron chelation; Myocardial T2

Indexed keywords

DEFERASIROX; IRON;

EID: 84862141974     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.049957     Document Type: Article
Times cited : (118)

References (27)
  • 3
    • 78650982192 scopus 로고    scopus 로고
    • Deferasirox, deferiprone and desferrioxamine treatment in thalassemia major patients: Cardiac iron and function comparison determined by quantitative Magnetic Resonance Imaging
    • Pepe A, Meloni A, Capra M, Cianciulli P, Prossomariti L, Malaventura C, et al. Deferasirox, deferiprone and desferrioxamine treatment in thalassemia major patients: cardiac iron and function comparison determined by quantitative Magnetic Resonance Imaging. Haematologica. 2011; 96(1):41-7.
    • (2011) Haematologica. , vol.96 , Issue.1 , pp. 41-47
    • Pepe, A.1    Meloni, A.2    Capra, M.3    Cianciulli, P.4    Prossomariti, L.5    Malaventura, C.6
  • 4
    • 0037125595 scopus 로고    scopus 로고
    • Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
    • Anderson LJ, Wonke B, Prescott E, Holden S, Walker JM, Pennell DJ. Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet. 2002;360(9332): 516-20.
    • (2002) Lancet. , vol.360 , Issue.9332 , pp. 516-520
    • Anderson, L.J.1    Wonke, B.2    Prescott, E.3    Holden, S.4    Walker, J.M.5    Pennell, D.J.6
  • 5
    • 7944230624 scopus 로고    scopus 로고
    • Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: A prospective study using T2* cardiovascular magnetic resonance
    • Anderson LJ, Westwood MA, Holden S, Davis B, Prescott E, Wonke B, et al. Myocardial iron clearance during reversal of siderotic cardiomyopathy with intravenous desferrioxamine: a prospective study using T2* cardiovascular magnetic resonance. Br J Haematol. 2004;127(3):348-55.
    • (2004) Br J Haematol. , vol.127 , Issue.3 , pp. 348-355
    • Anderson, L.J.1    Westwood, M.A.2    Holden, S.3    Davis, B.4    Prescott, E.5    Wonke, B.6
  • 6
    • 33646387405 scopus 로고    scopus 로고
    • Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis
    • Pennell DJ, Berdoukas V, Karagiorga M, Ladis V, Piga A, Aessopos A, et al. Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis. Blood. 2006;107(9):3738-44.
    • (2006) Blood. , vol.107 , Issue.9 , pp. 3738-3744
    • Pennell, D.J.1    Berdoukas, V.2    Karagiorga, M.3    Ladis, V.4    Piga, A.5    Aessopos, A.6
  • 7
    • 77950617863 scopus 로고    scopus 로고
    • Efficacy of deferasirox in reducing and preventing cardiac iron overload in c-thalassemia
    • Pennell DJ, Porter JB, Cappellini MD, El-Beshlawy A, Chan LL, Aydinok Y, et al. Efficacy of deferasirox in reducing and preventing cardiac iron overload in c-thalassemia. Blood. 2010;115(12):2364-71.
    • (2010) Blood. , vol.115 , Issue.12 , pp. 2364-2371
    • Pennell, D.J.1    Porter, J.B.2    Cappellini, M.D.3    El-Beshlawy, A.4    Chan, L.L.5    Aydinok, Y.6
  • 8
    • 78650996705 scopus 로고    scopus 로고
    • Continued improvement in myocardial T2* over 2 years of deferasirox therapy in othalassemia major patients with cardiac iron overload
    • Pennell DJ, Porter JB, Cappellini MD, Chan LL, El-Beshlawy A, Aydinok Y, et al. Continued improvement in myocardial T2* over 2 years of deferasirox therapy in othalassemia major patients with cardiac iron overload. Haematologica. 2011;96 (1):48-54.
    • (2011) Haematologica. , vol.96 , Issue.1 , pp. 48-54
    • Pennell, D.J.1    Porter, J.B.2    Cappellini, M.D.3    Chan, L.L.4    El-Beshlawy, A.5    Aydinok, Y.6
  • 9
    • 33645055937 scopus 로고    scopus 로고
    • Evaluation of the efficacy of oral deferiprone in beta-thalassemia major by multislice multiecho T2*
    • Pepe A, Lombardi M, Positano V, Cracolici E, Capra M, Malizia R, et al. Evaluation of the efficacy of oral deferiprone in beta-thalassemia major by multislice multiecho T2*. Eur J Haematol. 2006;76(3):183-92.
    • (2006) Eur J Haematol. , vol.76 , Issue.3 , pp. 183-192
    • Pepe, A.1    Lombardi, M.2    Positano, V.3    Cracolici, E.4    Capra, M.5    Malizia, R.6
  • 10
    • 34247103036 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance
    • Tanner MA, Galanello R, Dessi C, Smith GC, Westwood MA, Agus A, et al. A randomized, placebo-controlled, double-blind trial of the effect of combined therapy with deferoxamine and deferiprone on myocardial iron in thalassemia major using cardiovascular magnetic resonance. Circulation. 2007;115(4):1876-84.
    • (2007) Circulation. , vol.115 , Issue.4 , pp. 1876-1884
    • Tanner, M.A.1    Galanello, R.2    Dessi, C.3    Smith, G.C.4    Westwood, M.A.5    Agus, A.6
  • 11
    • 18044399191 scopus 로고    scopus 로고
    • Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload
    • Anderson LJ, Holden S, Davis B, Prescott E, Charrier CC, Bunce NH, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J. 2001; 22(23):2171-9.
    • (2001) Eur Heart J. , vol.22 , Issue.23 , pp. 2171-2179
    • Anderson, L.J.1    Holden, S.2    Davis, B.3    Prescott, E.4    Charrier, C.C.5    Bunce, N.H.6
  • 12
    • 77954345425 scopus 로고    scopus 로고
    • Relation of myocardial T2* to right ventricular function in thalassaemia major
    • Alpendurada F, Carpenter J-P, Deac M, Kirk P, Walker JM, Porter JB, et al. Relation of myocardial T2* to right ventricular function in thalassaemia major. Eur Heart J. 2010;31(13):1648-54.
    • (2010) Eur Heart J. , vol.31 , Issue.13 , pp. 1648-1654
    • Alpendurada, F.1    Carpenter, J-P.2    Deac, M.3    Kirk, P.4    Walker, J.M.5    Porter, J.B.6
  • 13
    • 72449177984 scopus 로고    scopus 로고
    • Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major
    • Kirk P, Roughton M, Porter JB, Walker JM, Tanner MA, Patel J, et al. Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major. Circulation. 2009;120(20):1961-8.
    • (2009) Circulation. , vol.120 , Issue.20 , pp. 1961-1968
    • Kirk, P.1    Roughton, M.2    Porter, J.B.3    Walker, J.M.4    Tanner, M.A.5    Patel, J.6
  • 15
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41.
    • (1976) Nephron. , vol.16 , Issue.1 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 16
    • 33747120659 scopus 로고    scopus 로고
    • Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate
    • Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, et al. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med. 2006;145(4):247-54.
    • (2006) Ann Intern Med. , vol.145 , Issue.4 , pp. 247-254
    • Levey, A.S.1    Coresh, J.2    Greene, T.3    Stevens, L.A.4    Zhang, Y.L.5    Hendriksen, S.6
  • 17
    • 77953779950 scopus 로고    scopus 로고
    • The effect of deferasirox on cardiac iron in thalassemia major: Impact of total body iron stores
    • Wood JC, Kang BP, Thompson A, Giardina P, Harmatz P, Glynos T, et al. The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores. Blood. 2010;116(4):537-43.
    • (2010) Blood. , vol.116 , Issue.4 , pp. 537-543
    • Wood, J.C.1    Kang, B.P.2    Thompson, A.3    Giardina, P.4    Harmatz, P.5    Glynos, T.6
  • 19
    • 0038187626 scopus 로고    scopus 로고
    • Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: A retrospective analysis
    • Piga A, Gaglioti C, Fogliacco E, Tricta F. Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: a retrospective analysis. Haematologica. 2003;88(5):489-96.
    • (2003) Haematologica. , vol.88 , Issue.5 , pp. 489-496
    • Piga, A.1    Gaglioti, C.2    Fogliacco, E.3    Tricta, F.4
  • 21
    • 77956957627 scopus 로고    scopus 로고
    • Relation of chelation regimes to cardiac mortality and morbidity in patients with thalassaemia major: An observational study from a large Greek unit
    • Ladis V, Chouliaras G, Berdoukas V, Moraitis P, Zannikos K, Berdoussi E, et al. Relation of chelation regimes to cardiac mortality and morbidity in patients with thalassaemia major: an observational study from a large Greek unit. Eur J Haematol. 2010;84(5):335-44.
    • (2010) Eur J Haematol. , vol.84 , Issue.5 , pp. 335-344
    • Ladis, V.1    Chouliaras, G.2    Berdoukas, V.3    Moraitis, P.4    Zannikos, K.5    Berdoussi, E.6
  • 22
    • 44049102508 scopus 로고    scopus 로고
    • Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction
    • Tanner MA, Galanello R, Dessi C, Smith GC, Westwood MA, Agus A, et al. Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction. J Cardiovasc Magn Reson. 2008;10:12.
    • (2008) J Cardiovasc Magn Reson. , vol.10 , pp. 12
    • Tanner, M.A.1    Galanello, R.2    Dessi, C.3    Smith, G.C.4    Westwood, M.A.5    Agus, A.6
  • 23
    • 78049273304 scopus 로고    scopus 로고
    • Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy
    • Kolnagou A, Kleanthous M, Kontoghi-orghes GJ. Reduction of body iron stores to normal range levels in thalassaemia by using a deferiprone/deferoxamine combination and their maintenance thereafter by deferiprone monotherapy. Eur J Haematol. 2010;85(5):430-8.
    • (2010) Eur J Haematol. , vol.85 , Issue.5 , pp. 430-438
    • Kolnagou, A.1    Kleanthous, M.2    Kontoghi-orghes, G.J.3
  • 24
    • 77957674350 scopus 로고    scopus 로고
    • Follow-up report on the 2-year cardiac data from a deferasirox monotherapy trial
    • Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, et al. Follow-up report on the 2-year cardiac data from a deferasirox monotherapy trial. Am J Hematol. 2010;85(10):818-9.
    • (2010) Am J Hematol. , vol.85 , Issue.10 , pp. 818-819
    • Wood, J.C.1    Glynos, T.2    Thompson, A.3    Giardina, P.4    Harmatz, P.5    Kang, B.P.6
  • 25
    • 58149402407 scopus 로고    scopus 로고
    • Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation
    • Kakhlon O, Manning H, Breuer W, Melamed-Book N, Lu C, Cortopassi G, et al. Cell functions impaired by frataxin deficiency are restored by drug-mediated iron relocation. Blood. 2008;112(13):5219-27.
    • (2008) Blood. , vol.112 , Issue.13 , pp. 5219-5227
    • Kakhlon, O.1    Manning, H.2    Breuer, W.3    Melamed-Book, N.4    Lu, C.5    Cortopassi, G.6
  • 26
    • 84855169923 scopus 로고    scopus 로고
    • On improvement in ejection fraction with iron chelation in thalassemia major and the risk of future heart failure
    • Pennell DJ, Carpenter J-P, Roughton M, Cabantchik IZ. On improvement in ejection fraction with iron chelation in thalassemia major and the risk of future heart failure. Cardiovasc Magn Reson. 2011; 13(1):45.
    • (2011) Cardiovasc Magn Reson. , vol.13 , Issue.1 , pp. 45
    • Pennell, D.J.1    Carpenter, J-P.2    Roughton, M.3    Cabantchik, I.Z.4
  • 27
    • 33646414765 scopus 로고    scopus 로고
    • A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with o-thalassemia
    • Cappellini MD, Cohen A, Piga A, Bejaoui M, Perrotta S, Agaoglu L, et al. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with o-thalassemia. Blood. 2006;107(9):3455-62.
    • (2006) Blood. , vol.107 , Issue.9 , pp. 3455-3462
    • Cappellini, M.D.1    Cohen, A.2    Piga, A.3    Bejaoui, M.4    Perrotta, S.5    Agaoglu, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.