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Volumn 19, Issue 4, 2012, Pages 256-260

Induced pluripotent stem cells in clinical hematology: Potentials, progress, and remaining obstacles

Author keywords

clinical hematology; hematopoietic differentiation; hematopoietic stem cell; induced pluripotency; reprogramming

Indexed keywords

CELL DIFFERENTIATION; CELL TRANSDIFFERENTIATION; EPIGENETICS; EX VIVO STUDY; GENE TARGETING; GENETIC VARIABILITY; HEMATOLOGIC DISEASE; HEMATOLOGY; HEMATOPOIETIC STEM CELL; HUMAN; IN VITRO STUDY; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; SOMATIC CELL; STEM CELL EXPANSION;

EID: 84862133325     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0b013e328353c78f     Document Type: Review
Times cited : (10)

References (34)
  • 2
    • 32944479985 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation and banking
    • DOI 10.1146/annurev.med.57.051804.123642
    • Brunstein CG, Wagner JE. Umbilical cord blood transplantation and banking. Annu Rev Med 2006; 57:403-417. (Pubitemid 43261998)
    • (2006) Annual Review of Medicine , vol.57 , pp. 403-417
    • Brunstein, C.G.1    Wagner, J.E.2
  • 3
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • Hanna J, Wernig M, Markoulaki S, et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007; 318:1920-1923.
    • (2007) Science , vol.318 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3
  • 4
    • 67650095306 scopus 로고    scopus 로고
    • Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
    • Raya A, Rodriguez-Piza I, Guenechea G, et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 2009; 460:53-59.
    • (2009) Nature , vol.460 , pp. 53-59
    • Raya, A.1    Rodriguez-Piza, I.2    Guenechea, G.3
  • 6
    • 0032483980 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science 1998; 282:1827.
    • (1998) Science , vol.282 , pp. 1827
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 7
    • 0037023544 scopus 로고    scopus 로고
    • HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors
    • DOI 10.1016/S0092-8674(02)00680-3
    • Kyba M, Perlingeiro RC, Daley GQ. HoxB4 confers definitive lymphoidmyeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 2002; 109:29-37. (Pubitemid 34327514)
    • (2002) Cell , vol.109 , Issue.1 , pp. 29-37
    • Kyba, M.1    Perlingeiro, R.C.R.2    Daley, G.Q.3
  • 8
    • 79960106880 scopus 로고    scopus 로고
    • Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment
    • Notta F, Doulatov S, Laurenti E, et al. Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science 2011; 333:218-221.
    • (2011) Science , vol.333 , pp. 218-221
    • Notta, F.1    Doulatov, S.2    Laurenti, E.3
  • 9
    • 78649471039 scopus 로고    scopus 로고
    • Direct conversion of human fibroblasts to multilineage blood progenitors
    • Szabo E, Rampalli S, Risueno RM, et al. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature 2010; 468:521-526.
    • (2010) Nature , vol.468 , pp. 521-526
    • Szabo, E.1    Rampalli, S.2    Risueno, R.M.3
  • 10
    • 77956519710 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
    • Boitano AE, Wang J, Romeo R, et al. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science 2010; 329:1345-1348.
    • (2010) Science , vol.329 , pp. 1345-1348
    • Boitano, A.E.1    Wang, J.2    Romeo, R.3
  • 11
    • 76349113345 scopus 로고    scopus 로고
    • Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution
    • Delaney C, Heimfeld S, Brashem-Stein C, et al. Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution. Nat Med 2010; 16:232-236.
    • (2010) Nat Med , vol.16 , pp. 232-236
    • Delaney, C.1    Heimfeld, S.2    Brashem-Stein, C.3
  • 12
    • 84863011896 scopus 로고    scopus 로고
    • Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling
    • Csaszar E, Kirouac DC, Yu M, et al. Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling. Cell Stem Cell 2012; 10:218-229.
    • (2012) Cell Stem Cell , vol.10 , pp. 218-229
    • Csaszar, E.1    Kirouac, D.C.2    Yu, M.3
  • 13
    • 79959461100 scopus 로고    scopus 로고
    • Ex vivo expansion of human hematopoietic stem and progenitor cells
    • Dahlberg A, Delaney C, Bernstein ID. Ex vivo expansion of human hematopoietic stem and progenitor cells. Blood 2011; 117:6083-6090.
    • (2011) Blood , vol.117 , pp. 6083-6090
    • Dahlberg, A.1    Delaney, C.2    Bernstein, I.D.3
  • 14
    • 79959480335 scopus 로고    scopus 로고
    • Potential clinical applications for human pluripotent stem cell-derived blood components
    • Kimbrel EA, Lu SJ. Potential clinical applications for human pluripotent stem cell-derived blood components. Stem Cells Int 2011; 273076.
    • (2011) Stem Cells Int , pp. 273076
    • Kimbrel, E.A.1    Lu, S.J.2
  • 15
    • 84856007232 scopus 로고    scopus 로고
    • The promise of induced pluripotent stem cells in research and therapy
    • Robinton DA, Daley GQ. The promise of induced pluripotent stem cells in research and therapy. Nature 2012; 481:295-305.
    • (2012) Nature , vol.481 , pp. 295-305
    • Robinton, D.A.1    Daley, G.Q.2
  • 16
    • 77957334627 scopus 로고    scopus 로고
    • Identification and classification of chromosomal aberrations in human induced pluripotent stem cells
    • Mayshar Y, Ben-David U, Lavon N, et al. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 2010; 7:521-531.
    • (2010) Cell Stem Cell , vol.7 , pp. 521-531
    • Mayshar, Y.1    Ben-David, U.2    Lavon, N.3
  • 17
    • 78650971216 scopus 로고    scopus 로고
    • Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture
    • Laurent LC, Ulitsky I, Slavin I, et al. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. Cell Stem Cell 2011; 8:106-118.
    • (2011) Cell Stem Cell , vol.8 , pp. 106-118
    • Laurent, L.C.1    Ulitsky, I.2    Slavin, I.3
  • 18
    • 79952258224 scopus 로고    scopus 로고
    • Somatic coding mutations in human induced pluripotent stem cells
    • Gore A, Li Z, Fung HL, et al. Somatic coding mutations in human induced pluripotent stem cells. Nature 2011; 471:63-67.
    • (2011) Nature , vol.471 , pp. 63-67
    • Gore, A.1    Li, Z.2    Fung, H.L.3
  • 19
    • 79952126043 scopus 로고    scopus 로고
    • Copy number variation and selection during reprogramming to pluripotency
    • Hussein SM, Batada NN, Vuoristo S, et al. Copy number variation and selection during reprogramming to pluripotency. Nature 2011; 471:58-62.
    • (2011) Nature , vol.471 , pp. 58-62
    • Hussein, S.M.1    Batada, N.N.2    Vuoristo, S.3
  • 20
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • Lister R, Pelizzola M, Kida YS, et al. Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 2011; 471:68-73.
    • (2011) Nature , vol.471 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.S.3
  • 21
    • 79958109873 scopus 로고    scopus 로고
    • Recurrent copy number variations in human induced pluripotent stem cells
    • Martins-Taylor K, Nisler BS, Taapken SM, et al. Recurrent copy number variations in human induced pluripotent stem cells. Nat Biotechnol 2011; 29:488-491.
    • (2011) Nat Biotechnol , vol.29 , pp. 488-491
    • Martins-Taylor, K.1    Nisler, B.S.2    Taapken, S.M.3
  • 22
    • 84863229606 scopus 로고    scopus 로고
    • Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression
    • Cheng L, Hansen NF, Zhao L, et al. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell 2012; 10:337-344.
    • (2012) Cell Stem Cell , vol.10 , pp. 337-344
    • Cheng, L.1    Hansen, N.F.2    Zhao, L.3
  • 24
    • 84855390254 scopus 로고    scopus 로고
    • Concise review: Genomic stability of human induced pluripotent stem cells
    • Martins-Taylor K, Xu RH. Concise review: genomic stability of human induced pluripotent stem cells. Stem Cells 2012; 30:22-27.
    • (2012) Stem Cells , vol.30 , pp. 22-27
    • Martins-Taylor, K.1    Xu, R.H.2
  • 25
    • 79957866291 scopus 로고    scopus 로고
    • Targeted gene correction of laminopathyassociated LMNA mutations in patient-specific iPSCs
    • Liu GH, Suzuki K, Qu J, et al. Targeted gene correction of laminopathyassociated LMNA mutations in patient-specific iPSCs. Cell Stem Cell 2011; 8:688-694.
    • (2011) Cell Stem Cell , vol.8 , pp. 688-694
    • Liu, G.H.1    Suzuki, K.2    Qu, J.3
  • 26
    • 82655168715 scopus 로고    scopus 로고
    • Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs
    • Li M, Suzuki K, Qu J, et al. Efficient correction of hemoglobinopathy- causing mutations by homologous recombination in integration-free patient iPSCs. Cell Res 2011; 21:1740-1744.
    • (2011) Cell Res , vol.21 , pp. 1740-1744
    • Li, M.1    Suzuki, K.2    Qu, J.3
  • 27
    • 79957587075 scopus 로고    scopus 로고
    • Oxidase-deficient neutrophils fromX-linked chronic granulomatous disease iPS cells: Functional correction by zinc finger nuclease-mediated safe harbor targeting
    • Zou J, Sweeney CL, Chou BK, et al. Oxidase-deficient neutrophils fromX-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting. Blood 2011; 117:5561-5672.
    • (2011) Blood , vol.117 , pp. 5561-5672
    • Zou, J.1    Sweeney, C.L.2    Chou, B.K.3
  • 28
    • 80055069793 scopus 로고    scopus 로고
    • Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
    • Zou J, Mali P, Huang X, et al. Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood 2011; 118:4599-4608.
    • (2011) Blood , vol.118 , pp. 4599-4608
    • Zou, J.1    Mali, P.2    Huang, X.3
  • 29
    • 79960833952 scopus 로고    scopus 로고
    • Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
    • Soldner F, Laganiere J, Cheng AW, et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 2011; 146:318-331.
    • (2011) Cell , vol.146 , pp. 318-331
    • Soldner, F.1    Laganiere, J.2    Cheng, A.W.3
  • 30
    • 79955574166 scopus 로고    scopus 로고
    • Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy
    • Howden SE, Gore A, Li Z, et al. Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. Proc Natl Acad Sci USA 2011; 108:6537-6542.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 6537-6542
    • Howden, S.E.1    Gore, A.2    Li, Z.3
  • 31
    • 80052050274 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction
    • Gaspar HB, Cooray S, Gilmour KC, et al. Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction. Sci Transl Med 2011; 3:97ra80.
    • (2011) Sci Transl Med , vol.3
    • Gaspar, H.B.1    Cooray, S.2    Gilmour, K.C.3
  • 32
    • 80052048463 scopus 로고    scopus 로고
    • Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency
    • Gaspar HB, Cooray S, Gilmour KC, et al. Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency. Sci Transl Med 2011; 3:97ra79.
    • (2011) Sci Transl Med , vol.3
    • Gaspar, H.B.1    Cooray, S.2    Gilmour, K.C.3
  • 33
    • 84857644799 scopus 로고    scopus 로고
    • Embryonic stem cell pioneer Geron exits field, cuts losses
    • Frantz S. Embryonic stem cell pioneer Geron exits field, cuts losses. Nat Biotechnol 2012; 30:12-13.
    • (2012) Nat Biotechnol , vol.30 , pp. 12-13
    • Frantz, S.1
  • 34
    • 84857643783 scopus 로고    scopus 로고
    • Embryonic stem cell trials for macular degeneration: A preliminary report
    • Schwartz SD, Hubschman JP, Heilwell G, et al. Embryonic stem cell trials for macular degeneration: a preliminary report. Lancet 2012; 379:713-720.
    • (2012) Lancet , vol.379 , pp. 713-720
    • Schwartz, S.D.1    Hubschman, J.P.2    Heilwell, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.