A novel method for high-throughput screening to quantify antiviral activity against viruses that induce limited CPE

Journal of Virological Methods

Volumn 183, Issue 2, 2012, Pages 176-179

  Jochmans, Dirk ^a   Leyssen, Pieter ^a   Neyts, Johan ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Antiviral assay; CPE quantitation; Fluorescent protease substrate; High throughput screening; Human coronavirus HCoV NL63

Indexed keywords

PROTEINASE;

ANTIVIRAL ACTIVITY; ARTICLE; CHILD; COLORIMETRY; CONTROLLED STUDY; CORONAVIRUS INFECTION; CYTOPATHOGENIC EFFECT; ENZYME SUBSTRATE; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; INCUBATION TIME; MALE; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN CLEAVAGE; VERO CELL; VIRUS DETECTION; VIRUS TITRATION;

ANIMALS; ANTIVIRAL AGENTS; CELL DEATH; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CORONAVIRUS NL63, HUMAN; FLUORESCENT DYES; HIGH-THROUGHPUT SCREENING ASSAYS; HOST-PATHOGEN INTERACTIONS; HUMANS; PEPTIDES; PROTEOLYSIS; VERO CELLS;

CORONAVIRUS;

EID: 84862120849     PISSN: 01660934     EISSN: 18790984     Source Type: Journal    
DOI: 10.1016/j.jviromet.2012.04.011     Document Type: Article

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