Airway responsiveness depends on the diffusion rate of methacholine across the airway wall

Journal of Applied Physiology

Volumn 112, Issue 10, 2012, Pages 1670-1677

  Bates, Jason H T ^a   Stevenson, Chelsea A ^a   Aliyeva, Minara ^a   Lundblad, Lennart K A ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Airway resistance; Computational model; Hyperresponsiveness; Mouse model

Indexed keywords

BRONCHOCONSTRICTING AGENT; DIAGNOSTIC AGENT; METHACHOLINE CHLORIDE; OVALBUMIN;

AEROSOL; AIRWAY RESISTANCE; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOLOGICAL MODEL; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CHEMICALLY INDUCED DISORDER; COMPUTER SIMULATION; DIFFUSION; DISEASE MODEL; DOSE RESPONSE; INHALATION TEST; INHALATIONAL DRUG ADMINISTRATION; LUNG; METABOLISM; MOUSE; PATHOPHYSIOLOGY; PERMEABILITY; SMOOTH MUSCLE;

ADMINISTRATION, INHALATION; AEROSOLS; AIRWAY RESISTANCE; ANIMALS; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; BRONCHOCONSTRICTION; BRONCHOCONSTRICTOR AGENTS; COMPUTER SIMULATION; DIFFUSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; LUNG; METHACHOLINE CHLORIDE; MICE; MICE, INBRED BALB C; MODELS, BIOLOGICAL; MUSCLE, SMOOTH; OVALBUMIN; PERMEABILITY;

EID: 84862063485     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00703.2011     Document Type: Article

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