Changes in measurement procedure from a radioassay to a microbiologic assay necessitate adjustment of serum and RBC folate concentrations in the U.S. population from the NHANES 1988-2010

Journal of Nutrition

Volumn 142, Issue 5, 2012, Pages 894-900

  Pfeiffer, Christine M ^a   Hughes, Jeffery P ^b   Durazo Arvizu, Ramon A ^c   Lacher, David A ^b   Sempos, Christopher T ^d   Zhang, Mindy ^a   Yetley, Elizabeth A ^d   Johnson, Clifford L ^a  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b NATIONAL CENTER FOR HEALTH STATISTICS   (United States)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLIC ACID;

ARTICLE; BIOTRANSFORMATION; BLOOD SAMPLING; CHILD; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ERYTHROCYTE; FOLIC ACID BLOOD LEVEL; FOLIC ACID DEFICIENCY; FRACTIONAL POLYNOMIAL REGRESSION ANALYSIS; HEALTH SURVEY; HUMAN; LINEAR REGRESSION ANALYSIS; LONG TERM CARE; MAJOR CLINICAL STUDY; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; NATIONAL HEALTH ORGANIZATION; PIECEWISE LINEAR REGRESSION ANALYSIS; PRESCHOOL CHILD; PREVALENCE; RADIOASSAY; REGRESSION ANALYSIS; SENSITIVITY AND SPECIFICITY; SERUM; TREND STUDY; UNITED STATES;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; ERYTHROCYTES; FEMALE; FOLIC ACID; FOLIC ACID DEFICIENCY; HUMANS; MALE; MICROBIOLOGICAL TECHNIQUES; MIDDLE AGED; NUTRITION SURVEYS; PREVALENCE; RADIOLIGAND ASSAY; UNITED STATES; YOUNG ADULT;

EID: 84862062809     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.156901     Document Type: Article

References (25)

1. Yetley EA, Johnson CL. Folate and vitamin B-12 biomarkers in NHANES: history of their measurement and use. Am J Clin Nutr. 2011;94 Suppl:322S-31S.
2. Yetley EA, Pfeiffer CM, Phinney KW, Fazili Z, Lacher DA, Bailey RL, Blackmore S, Bock JL, Brody LC, Carmel R, et al. Biomarkers of folate status in the National Health and Nutrition Examination Survey (NHANES): a roundtable summary. Am J Clin Nutr. 2011;94 Suppl:303S-12S.
3. Raiten DJ, Fisher KD. Assessment of folate methodology used in the third National Health and Nutrition Examination Survey (NHANES III, 1988-1994). J Nutr. 1995;125:1371S-98S.
4. Fazili Z, Pfeiffer CM, Zhang M. Comparison of serum folate species analyzed by LC-MS/MS with total folate measured by microbiologic assay and BioRad radioassay. Clin Chem. 2007;53:781-4.
5. Fazili Z, Pfeiffer CM, Zhang M, Jain RB, Koontz D. Influence of 5,10- methylene-tetrahydrofolate reductase polymorphism on whole blood folate concentrations measured by LC-MS/MS, microbiologic assay and BioRad radioassay. Clin Chem. 2008;54:197-201.
6. Yetley EA, Coates PM, Johnson CL. Overview of a roundtable on NHANES monitoring of biomarkers of folate and vitamin B-12 status: measurement procedure issues. Am J Clin Nutr. 2011;94 Suppl:297S-302S.
7. Senti FR, Pilch SM. Analysis of folate data from the Second National Health and Nutrition Examination Survey (NHANES II). J Nutr. 1985;115:1398-402.
8. Pfeiffer CM, Hughes JP, Lacher DA, Bailey RL, Berry RJ, Yetley EA, Zhang M, Yetley EA, Rader JI, Sempos CT, et al. Trends in serum and red blood cell folate in the U.S. population from pre- to postfortification: National Health and Nutrition Examination Survey 1988-2010. J Nutr. 2011.
9. Centers for Disease Control and Prevention, National Center for Health Statistics. National Health and Nutrition Examination Survey, 2007-2008 [cited 2011 Dec 17]. Available from: http://www.cdc.gov/nchs/data/nhanes/nhanes_07_08/overviewbrochure_0708.pdf.
10. Centers for Disease Control and Prevention, National Center for Health Statistics. 2007-2008 Serum and red blood cell folate [cited 2011 Dec 17]. Available from: http://www.cdc.gov/nchs/nhanes/nhanes2007-2008/FOLATE_E.htm.
11. Centers for Disease Control and Prevention, National Center for Health Statistics.2009-2010 Serum and red blood cell folate [cited 2011 Dec 17]. Available from: http://www.cdc.gov/nchs/nhanes/nhanes2009-2010/ FOLATE_F.htm.
12. O'Broin S, Kelleher B. Microbiological assay on microtitre plates of folate in serum and red cells. J Clin Pathol. 1992;45:344-7.
13. Molloy AM, Scott JM. Microbiological assay for serum, plasma, and red cell folate using cryopreserved, microtiter plate method. Methods Enzymol. 1997;281:43-53.
14. Pfeiffer CM, Zhang M, Lacher DA, Molloy AM, Tamura T, Yetley EA, Picciano M-F, Johnson CL. Comparison of serum and red blood cell folate microbiologic assays for national population surveys. J Nutr. 2011;141:1402-9.
15. Centers for Disease Control and Prevention, National Center for Health Statistics. Total folate by microbiological assay [cited 2011 Dec 17]. Available from: http://www.cdc.gov/nchs/data/nhanes/nhanes_07_08/ folate_b12_d_met.pdf.
16. Centers for Disease Control and Prevention, National Center for Health Statistics. Total folate by microbiological assay [cited 2011 Dec 17]. Available from: http://www.cdc.gov/NCHS/data/nhanes/nhanes_09_10/ FOLATE_F_met.pdf.
17. Satterfield MB, Sniegoski LT, Sharpless KE, Welch MJ, Hornikova A, Zhang N-F, Pfeiffer CM, Fazili Z, Zhang M, Nelson BC. Development of a new standard reference material: SRM 1955 (homocysteine and folate in human serum). Anal Bioanal Chem. 2006;385:612-22.
18. Thorpe SJ, Heath A, Blackmore S, Lee A, Hamilton M, O'Broin S, Nelson BC, Pfeiffer CM. An international standard for serum vitamin B12 and serum folate: International collaborative study to evaluate a batch of lyophilized serum for B12 and folate content. Clin Chem Lab Med. 2007;45:380-6.
19. Thorpe SJ, Sands D, Heath AB, Hamilton M, Blackmore S, Barrowcliffe T. An international standard for whole blood folate: evaluation of a lyophilised haemolysate in an international collaborative study. Clin Chem Lab Med. 2004;42:533-9.
20. U.K. National External Quality Assessment Scheme for Haematinic Assays. [cited 2012 Feb 5]. Available from: http://www.ukneqas-haematinics.org. uk/content/Pageserver.asp.
21. Pfeiffer CM, Johnson CL, Jain RB, Yetley EA, Picciano MF, Rader JI, Fisher KD, Mulinare J, Osterloh JD. Trends in blood folate and vitamin B12 concentrations in the United States, 1988-2004. Am J Clin Nutr. 2007;86:718-27.
22. Royston P, Altman DG. Regression using fractional polynomials of continuous covariates: parsimonious parametric modeling. Appl Stat. 1994;43:429-67.
23. Shane B. Folate status assessment history: implications for measurement of biomarkers in NHANES. Am J Clin Nutr. 2011;94 Suppl:337S-42S.
24. Blackmore S, Pfeiffer CM, Lee A, Fazili Z, Hamilton MS. Assessment of the accuracy of serum folate assays and a proficiency testing consensus mean by an isotope dilution liquid chromatography tandem-mass spectrometry reference method. Clin Chem. 2011;57:986-94.
25. Pfeiffer CM, Fazili Z, ZhangM. Folate analytical methodology. In: Bailey LB, editor. Folate in health and disease. 2nd ed. Boca Raton, FL: CRC Press; 2010.