Flt3-ITD mutations in a mouse model of radiation-induced acute myeloid leukaemia

Leukemia

Volumn 26, Issue 6, 2012, Pages 1445-1446

  Finnon, R ^a   Brown, N ^a   Moody, J ^a   Badie, C ^a   Olme, C H ^a   Huiskamp, R ^b   Meijne, E ^c   Sutmuller, M ^b   Rosemann, M ^d   Bouffler, S D ^a  

^a PUBLIC HEALTH ENGLAND   (United Kingdom)

^b NUCLEAR RESEARCH AND CONSULTANCY GROUP NRG   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; CHROMOSOME 2; CHROMOSOME DELETION; DNA EXTRACTION; FLT3 GENE; GENE; GENE MUTATION; GENETIC ANALYSIS; LETTER; MOUSE; NONHUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADIATION INJURY;

ANIMALS; DISEASE MODELS, ANIMAL; DNA, NEOPLASM; FMS-LIKE TYROSINE KINASE 3; LEUKEMIA, MYELOID, ACUTE; LEUKEMIA, RADIATION-INDUCED; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MUTATION; POLYMERASE CHAIN REACTION; TANDEM REPEAT SEQUENCES; X-RAYS;

EID: 84862023915     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.377     Document Type: Letter

References (8)

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3. Suraweera N, Meijne E, Moody J, Carvajal-Carmona L, Yoshida K, Pollard P et al. Mutations of the PU.1 etc domain are specifically associated with murine radiationinduced, but not human therapy-related acute myeloid leukaemia. Oncogene 2005; 24: 3678-3683. (Pubitemid 40756237)
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6. Small D. Flt3 mutations: biology and treatment. Hematology Am Soc Hematol Educ Program 2006, 178-184. Review.
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8. Kiyoi H, Towatari M, Yokota S, Hamaguchi M, Ohno R, Saito H et al. Internal tandem duplication of the Flt3 gene is a novel modality of enlongation mutation which causes constitutive activation of the product. Leukaemia 1998; 12: 1333-1337. (Pubitemid 28442377)