In vivo wound-healing efficacy and antioxidant activity of Achyranthes aspera in experimental burns

Pharmaceutical Biology

Volumn 50, Issue 7, 2012, Pages 892-899

  Barua, Chandana Choudhury ^a   Talukdar, Archana ^a   Begum, Shameem Ara ^a   Pathak, Debesh Chandra ^a   Sarma, Dilip Kumar ^a   Borah, Rumi Saikia ^a   Gupta, Asheesh ^b  

^a Uttar Pradesh Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go Anusandhan Sansthan   (India)

^b DEFENCE INSTITUTE OF PHYSIOLOGY AND ALLIED SCIENCES   (India)

Author keywords

Achyranthes aspera; angiogenesis; antioxidants; catalase; collagen; hydroxyproline; matrix metalloproteinase

Indexed keywords

ACHYRANTHES ASPERA EXTRACT; ASCORBIC ACID; CATALASE; COLLAGEN; DERMATOLOGICAL AGENT; GELATINASE A; GELATINASE B; HIMAX; HYDROXYPROLINE; METHANOL; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMISTRY; BURN; CELL PROLIFERATION; COLLAGEN METABOLISM; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; ENZYME ACTIVITY; ENZYME REGULATION; EPIDERMIS; FEMALE; FIBROBLAST; GELATIN ZYMOGRAPHY; GRANULATION TISSUE; HISTOPATHOLOGY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OINTMENT; PLANT LEAF; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; SKIN TOXICITY; TOXICITY TESTING; TREATMENT DURATION; UPREGULATION; WOUND CONTRACTION; WOUND HEALING; ZYMOGRAPHY;

ACHYRANTHES; ADMINISTRATION, TOPICAL; ANIMALS; ANTIOXIDANTS; BURNS; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; PLANT EXTRACTS; PLANT LEAVES; RATS; TREATMENT OUTCOME; WOUND HEALING;

ACHYRANTHES; ACHYRANTHES ASPERA; AMARANTHACEAE; ANIMALIA; RATTUS;

EID: 84862021098     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2011.642885     Document Type: Article

References (34)

1. Aebi H. (1984). Catalase-Methods of Enzymatic Analysis. New York: Academic Press.
2. Aziz A, Rahman M, Mondal AK, Muslim T, Rahman A, Quader A. (2005). 3-Acetoxy-6-benzoyloxyapagamide from Achyranthes aspera. Pharmaceutical J, 4, 1816-1820.
3. Barua CC, Begum SA, Talukdar A, Barua AG, Borah P, Lahkar M. (2010a). Effect of Achyranthes aspera on modified forced swimming in rats. Pharmacologyonline, 1, 183-191.
4. Barua CC, Begum SA, Talukdar A, Pathak DC, Sarma DK, Bora RS. (2010b). Wound healing activity of methanolic extract of leaves of Achyranthes aspera Linn using in vivo and in vitro model - a preliminary study. Indian J Anim Sci, 80, 969-972.
5. Barua CC, Talukdar A, Begum SA, Buragohain B, Roy JD, Borah RS, Lahkar M. (2009). Antidepressant-like effects of the methanol extract of Achyranthes aspera Linn. in animal models of depression. Pharmacologyonline, 2, 587-594.
6. Barua CC, Talukdar A, Begum SA, Lahon LC, Sarma DK, Pathak DC, Borah P. (2010c). Antinociceptive activity of methanolic extract of leaves of Achyranthes aspera Linn. (Amaranthaceae) in animal models of nociception. Indian J Exp Biol, 48, 817-821.
7. Beutler E, Duron O, Kelly BM. (1963). Improved method for the determination of blood glutathione. J Lab Clin Med, 61, 882-888.
8. Chakraborty A, Brantner A, Mukainaka T, Nobukuni Y, Kuchide M, Konoshima T, Tokuda H, Nishino H. (2002). Cancer chemopreventive activity of Achyranthes aspera leaves on Epstein- Barr virus activation and two-stage mouse skin carcinogenesis. Cancer Lett, 177, 1-5. (Pubitemid 34102392)
9. Chan K. (2003). Some aspects of toxic contaminants in herbal medicines. Chemosphere, 52, 1361-1371.
10. Clark RA. (1996). Wound Repair: An Overview and General Consideration-Molecular and Cellular Biology of Wound Repair. New York: Plenum Press.
11. Dhiman SC, Bhardwaj P. (2010). Global warming in relation to the occurrence of medicinal plant, Ocimum basilicum Linn. and its tingid bug Monanthia globulifera Walker. J Env Bio Sci, 24, 175-178.
12. Dissemond J, Goos M, Wagner SN. (2002). The role of oxidative stress in the pathogenesis and therapy of chronic wounds. Hautarzt, 53, 718-723. (Pubitemid 36069821)
13. Fridovich I. (1978). The biology of oxygen radicals. Science, 201, 875-880.
14. Gupta A, Upadhyay NK, Sawhney RC, Kumar R. (2008). A poly-herbal formulation accelerates normal and impaired diabetic wound healing. Wound Repair Regen, 16, 784-790.
15. Iba Y, Shibata A, Kato M, Masukawa T. (2004). Possible involvement of mast cells in collagen remodeling in the late phase of cutaneous wound healing in mice. Int Immunopharmacol, 4, 1873-1880. (Pubitemid 39504827)
16. Inkinen K, Turakainen H, Wolff H, Ravanti L, Kähäri VM, Ahonen J. (2000). Expression and activity of matrix metalloproteinase-2 and -9 in experimental granulation tissue. APMIS, 108, 318-328. (Pubitemid 30456360)
17. Jocelyn H, Bruce-Gregorios MD. (1974). Histopathologic Techniques, Philippines: JMC Press Inc.
18. Kartik R, Rao ChV, Trivedi SP, Pushpangadan P, Reddy GD. (2010). Amelioration effects against N-nitrosodiethylamine and CCl(4)-induced hepatocarcinogenesis in Swiss albino rats by whole plant extract of Achyranthes aspera. Indian J Pharmacol, 42, 370-375.
19. Lee G, Luna HT. (1968). Manual of Histological Staining Methods of the Armed Forces. 3rd ed., New York: Institute of Pathology, American Registry of Pathology, Blakiston Division.
20. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. (1951). Protein measurement with the Folin phenol reagent. J Biol Chem, 193, 265-275.
21. MacKay D, Miller AL. (2003). Nutritional support for wound healing. Altern Med Rev, 8, 359-377. (Pubitemid 37493867)
22. Marklund S, Marklund G. (1974). Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem, 47, 469-474.
23. Mavelli I, Rigo A, Federico R, Ciriolo MR, Rotilio G. (1982). Superoxide dismutase, glutathione peroxidase and catalase in developing rat brain. Biochem J, 204, 535-540. (Pubitemid 12053550)
24. Pierce GF, Mustoe TA. (1995). Pharmacologic enhancement of wound healing. Annu Rev Med, 46, 467-481.
25. Priya KS, Gnanamani A, Radhakrishnan N, Babu M. (2002). Healing potential of Datura alba on burn wounds in albino rats. J Ethnopharmacol, 83, 193-199. (Pubitemid 35333210)
26. Rae JH. (1984). Chemical Determination of Ascorbic Acid, Dehydroascorbic Acid and Diketogluconic Acids - Methods of Biochemical Analysis. New York: Interscience Publishers.
27. Riley V. (1960). Adaptation of orbital bleeding technic to rapid serial blood studies. Proc Soc Exp Biol Med, 104, 751-754.
28. Sandhyakumary K, Boby RG, Indira M. (2002). Impact of feeding ethanolic extracts of Achyranthes aspera Linn. on reproductive functions in male rats. Indian J Exp Biol, 40, 1307-1309. (Pubitemid 35307165)
29. Scortichini M, Pia RM. (1991). Preliminary in vitro evaluation of the antimicrobial activity of triterpenes and terpenoids towards Erwinia amylovora (Burrill). J Bacteriol, 71, 109-112.
30. Singer AJ, Clark RA. (1999). Cutaneous wound healing. N Engl J Med, 341, 738-746. (Pubitemid 29407375)
31. Upadhyay NK, Kumar R, Mandotra SK, Meena RN, Siddiqui MS, Sawhney RC, Gupta A. (2009). Safety and healing efficacy of Sea buckthorn (Hippophae rhamnoides L.) seed oil on burn wounds in rats. Food Chem Toxicol, 47, 1146-1153.
32. Vetrichelvan T, Jegadeesan M. (2003). Effect of alcohol extract of Achyranthes aspera Linn. on acute and subacute inflammation. Phytother Res, 17, 77-79. (Pubitemid 36205464)
33. Woessner Jfr JF. (1961). The determination of hydroxyproline in tissue and protein sample containing small proportions of this amino acid. Arch Biochem Biophys, 93, 440-447.
34. Workineh S, Eyasu M, Legesse Z, Asfaw D. (2006) Effect of Achyranthes aspera L. on fetal abortion, uterine and pituitary weights, serum lipids and hormones. African Health Sciences, 6, 108-112.