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Volumn 176, Issue 1, 2012, Pages 147-153

Multiple kinase pathways involved in the different de novo sensitivity of pancreatic cancer cell lines to 17-AAG

Author keywords

17 AAG; chemosensitivity; kinase; pancreatic cancer

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOPROTEIN P; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN P53; PROTEIN S6; SMALL INTERFERING RNA; SORAFENIB; TANESPIMYCIN;

EID: 84862001413     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.09.017     Document Type: Article
Times cited : (3)

References (26)
  • 1
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signaling
    • P. Blume-Jensen, and T. Hunter Oncogenic kinase signaling Nature 411 2001 355
    • (2001) Nature , vol.411 , pp. 355
    • Blume-Jensen, P.1    Hunter, T.2
  • 2
    • 0028064940 scopus 로고
    • Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: Essential role for stress proteins in oncogenic transformation
    • L. Whitesell, E.G. Mimnaugh, and B. De Costa Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: Essential role for stress proteins in oncogenic transformation Proc Natl Acad Sci U S A 91 1994 8324
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 8324
    • Whitesell, L.1    Mimnaugh, E.G.2    De Costa, B.3
  • 3
    • 0029008487 scopus 로고
    • Herbimycin A induces the 20 S proteasome- and ubiquitin-dependent degradation of receptor tyrosine kinases
    • L. Sepp-Lorenzino, Z. Ma, and D.E. Lebwohl Herbimycin A induces the 20 S proteasome- and ubiquitin-dependent degradation of receptor tyrosine kinases J Biol Chem 270 1995 16580
    • (1995) J Biol Chem , vol.270 , pp. 16580
    • Sepp-Lorenzino, L.1    Ma, Z.2    Lebwohl, D.E.3
  • 4
    • 0029812759 scopus 로고    scopus 로고
    • Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin
    • E.G. Mimnaugh, C. Chavany, and L. Neckers Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin J Biol Chem 271 1996 22796
    • (1996) J Biol Chem , vol.271 , pp. 22796
    • Mimnaugh, E.G.1    Chavany, C.2    Neckers, L.3
  • 5
    • 2642521990 scopus 로고    scopus 로고
    • Therapeutic and diagnostic implications of Hsp90 activation
    • A. Kamal, M.F. Boehm, and F.J. Burrows Therapeutic and diagnostic implications of Hsp90 activation Trends Mol Med 10 2004 283
    • (2004) Trends Mol Med , vol.10 , pp. 283
    • Kamal, A.1    Boehm, M.F.2    Burrows, F.J.3
  • 6
    • 33746379315 scopus 로고    scopus 로고
    • Using natural product inhibitors to validate Hsp90 as a molecular target in cancer
    • L. Neckers Using natural product inhibitors to validate Hsp90 as a molecular target in cancer Curr Top Med Chem 6 2006 1163
    • (2006) Curr Top Med Chem , vol.6 , pp. 1163
    • Neckers, L.1
  • 7
    • 36849055007 scopus 로고    scopus 로고
    • Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: A phase i dose-escalation study
    • S. Modi, A.T. Stopeck, and M.S. Gordon Combination of trastuzumab and tanespimycin (17-AAG, KOS-953) is safe and active in trastuzumab-refractory HER-2 overexpressing breast cancer: A phase I dose-escalation study J Clin Oncol 25 2007 5410
    • (2007) J Clin Oncol , vol.25 , pp. 5410
    • Modi, S.1    Stopeck, A.T.2    Gordon, M.S.3
  • 8
    • 34250837082 scopus 로고    scopus 로고
    • A strategic framework for novel drug development in multiple myeloma
    • K.C. Anderson, A.L. Hannah, and R. Pazdur A strategic framework for novel drug development in multiple myeloma Br J Haematol 138 2007 153
    • (2007) Br J Haematol , vol.138 , pp. 153
    • Anderson, K.C.1    Hannah, A.L.2    Pazdur, R.3
  • 9
    • 58149340657 scopus 로고    scopus 로고
    • Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma
    • D.B. Solit, I. Osman, and D. Polsky Phase II trial of 17-allylamino-17-demethoxygeldanamycin in patients with metastatic melanoma Clin Cancer Res 14 2008 8302
    • (2008) Clin Cancer Res , vol.14 , pp. 8302
    • Solit, D.B.1    Osman, I.2    Polsky, D.3
  • 10
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • J.A. Endicott, and V. Ling The biochemistry of P-glycoprotein-mediated multidrug resistance Annu Rev Biochem 58 1989 137
    • (1989) Annu Rev Biochem , vol.58 , pp. 137
    • Endicott, J.A.1    Ling, V.2
  • 11
    • 54749126264 scopus 로고    scopus 로고
    • P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response
    • A.K. McCollum, C.J. TenEyck, and B. Stensgard P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response Cancer Res 68 2008 7419
    • (2008) Cancer Res , vol.68 , pp. 7419
    • McCollum, A.K.1    Teneyck, C.J.2    Stensgard, B.3
  • 12
    • 0028104545 scopus 로고
    • Mechanisms of resistance to ansamycin antibiotics in human breast cancer cell lines
    • M.N. Benchekroun, E. Schneider, and A.R. Safa Mechanisms of resistance to ansamycin antibiotics in human breast cancer cell lines Mol Pharmacol 46 1994 677
    • (1994) Mol Pharmacol , vol.46 , pp. 677
    • Benchekroun, M.N.1    Schneider, E.2    Safa, A.R.3
  • 13
    • 0029038135 scopus 로고
    • Apoptosis, cancer and the p53 tumor suppressor gene
    • J.M. Lee, and A. Bernstein Apoptosis, cancer and the p53 tumor suppressor gene Cancer Metastasis Rev 14 1995 149
    • (1995) Cancer Metastasis Rev , vol.14 , pp. 149
    • Lee, J.M.1    Bernstein, A.2
  • 14
    • 13644260907 scopus 로고    scopus 로고
    • Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
    • G.A. Lang, T. Iwakuma, and Y.A. Suh Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome Cell 119 2004 861
    • (2004) Cell , vol.119 , pp. 861
    • Lang, G.A.1    Iwakuma, T.2    Suh, Y.A.3
  • 15
    • 0029737509 scopus 로고    scopus 로고
    • Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90
    • M.V. Blagosklonny, J. Toretsky, and S. Bohen Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90 Proc Natl Acad Sci USA 93 1996 8379
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8379
    • Blagosklonny, M.V.1    Toretsky, J.2    Bohen, S.3
  • 16
    • 0027451668 scopus 로고    scopus 로고
    • P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • S.W. Lowe, H.E. Ruley, and T. Jacks p53-dependent apoptosis modulates the cytotoxicity of anticancer agents Cell 74 1996 957
    • (1996) Cell , vol.74 , pp. 957
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3
  • 17
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680
    • (1970) Nature , vol.227 , pp. 680
    • Laemmli, U.K.1
  • 18
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • T. Mosmann Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays J Immunol Methods 65 1983 55
    • (1983) J Immunol Methods , vol.65 , pp. 55
    • Mosmann, T.1
  • 19
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • T.C. Chou, and P. Talalay Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors Adv Enzyme Regul 22 1984 27
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27
    • Chou, T.C.1    Talalay, P.2
  • 20
    • 0031035181 scopus 로고    scopus 로고
    • An information-intensive approach to the molecular pharmacology of cancer
    • J.N. Weinstein, T.G. Myers, and P.M. O'Connor An information-intensive approach to the molecular pharmacology of cancer Science 275 1997 343
    • (1997) Science , vol.275 , pp. 343
    • Weinstein, J.N.1    Myers, T.G.2    O'Connor, P.M.3
  • 21
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • J. Zha, H. Harada, and E. Yang Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) Cell 87 1996 619
    • (1996) Cell , vol.87 , pp. 619
    • Zha, J.1    Harada, H.2    Yang, E.3
  • 22
    • 34547638990 scopus 로고    scopus 로고
    • Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1
    • Y. Huang, P.E. Blower, and R. Liu Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1 Pharm Res 24 2007 1702
    • (2007) Pharm Res , vol.24 , pp. 1702
    • Huang, Y.1    Blower, P.E.2    Liu, R.3
  • 23
    • 23044472299 scopus 로고    scopus 로고
    • P-glycoprotein-independent apoptosis induction by a novel synthetic compound, MMPT [5-[(4-methylphenyl)methylene]-2-(phenylamino)-4(5H)-thiazolone]
    • F. Teraishi, S. Wu, and J. Sasaki P-glycoprotein-independent apoptosis induction by a novel synthetic compound, MMPT [5-[(4-methylphenyl)methylene]-2- (phenylamino)-4(5H)-thiazolone] J Pharmacol Exp Ther 314 2005 355
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 355
    • Teraishi, F.1    Wu, S.2    Sasaki, J.3
  • 24
    • 67650999217 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer
    • T. Arumugam, V. Ramachandran, and K.F. Fournier Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer Cancer Res 69 2009 5820
    • (2009) Cancer Res , vol.69 , pp. 5820
    • Arumugam, T.1    Ramachandran, V.2    Fournier, K.F.3
  • 25
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • S.M. Wilhelm, C. Carter, and L. Tang BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis Cancer Res 64 2004 7099
    • (2004) Cancer Res , vol.64 , pp. 7099
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3
  • 26
    • 34447507818 scopus 로고    scopus 로고
    • Inhibitors of the heat shock response: Biology and pharmacology
    • M.V. Powers, and P. Workman Inhibitors of the heat shock response: Biology and pharmacology FEBS Lett 581 2007 3758
    • (2007) FEBS Lett , vol.581 , pp. 3758
    • Powers, M.V.1    Workman, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.