The vitamin e derivative, EPC-K1, suppresses inflammation during hepatic ischemia-reperfusion injury and exerts hepatoprotective effects in rats

Journal of Surgical Research

Volumn 176, Issue 1, 2012, Pages 164-170

  Oishi, Kazushige ^a   Hagiwara, Satoshi ^b   Koga, Satoko ^a   Kawabe, Satoshi ^a   Uno, Takahiro ^a   Iwasaka, Hideo ^b   Noguchi, Takayuki ^b  

^a NATIONAL HOSPITAL ORGANIZATION BEPPU MEDICAL CENTER   (Japan)

^b OITA UNIVERSITY   (Japan)

Author keywords

apoptosis; EPC K1; hepatic ischemia reperfusion injury; mitochondria; necrosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL DERIVATIVE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 7; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LEVO ASCORBIC ACID 2 [3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2 (4,8,12 TRIMETHYLTRIDECYL) 2H 1 BENZOPYRAN 6 YL HYDROGEN PHOSPHATE]POTASSIUM; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CYTOKINE RELEASE; ENZYME ACTIVITY; GENERAL ANESTHESIA; HEPATIC ARTERY; HISTOPATHOLOGY; HYPOTHESIS; IN VIVO STUDY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER; LIVER FUNCTION; LIVER INJURY; LIVER ISCHEMIA; LIVER PROTECTION; MALE; NICK END LABELING; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPERFUSION; REPERFUSION INJURY; SYSTEMATIC REVIEW;

ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASES; HMGB1 PROTEIN; INFLAMMATION; INJECTIONS, SUBCUTANEOUS; INTERLEUKIN-6; L-LACTATE DEHYDROGENASE; LIVER; MALE; MODELS, ANIMAL; RATS; RATS, WISTAR; REPERFUSION INJURY; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN E;

EID: 84862000682     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.03.080     Document Type: Article

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