Systems biology approach to transplant tolerance: Proof of concept experiments using RNA interference (RNAi) to knock down hub genes in Jurkat and hela cells in vitro

Journal of Surgical Research

Volumn 176, Issue 1, 2012, Pages

  Lwin, Wint Wah ^a,b   Park, Ken ^a   Wauson, Matthew ^a   Gao, Qin ^a   Finn, Patricia W ^b   Perkins, David ^a   Khanna, Ajai ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

hub genes; Jurkat cells; knockdown; siRNA; systems biology; transplant tolerance

Indexed keywords

SMALL INTERFERING RNA;

ARTICLE; ATP5C1 GENE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; GENE; GENE INTERACTION; GENE REPRESSION; GENE SILENCING; GENETIC ALGORITHM; HELA CELL; HUB GENE; HUMAN; HUMAN CELL; IL6ST GENE; IMMUNOSTIMULATION; IN VITRO STUDY; LEUKEMIA CELL LINE; MAPK1 GENE; MOLECULAR INTERACTION; ONCOGENE C FOS; ONCOGENE MYC; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PRKCZ GENE; RNA INTERFERENCE; SYSTEMS BIOLOGY;

ADENOSINE TRIPHOSPHATE; CELL LINE; CELL PROLIFERATION; GENE KNOCKDOWN TECHNIQUES; GRAFT REJECTION; HELA CELLS; HUMANS; IMMUNE TOLERANCE; JURKAT CELLS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SYSTEMS BIOLOGY; T-LYMPHOCYTES; TRANSFECTION;

EID: 84862000597     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.12.002     Document Type: Article

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