Small ubiquitin-like modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in Vitro and in Vivo

Journal of Biological Chemistry

Volumn 287, Issue 24, 2012, Pages 20483-20489

  Han, Lizhang ^a,b   Pan, Yong ^b   Wang, Baolin ^b  

^a SHANDONG UNIVERSITY   (China)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE RESIDUE; CELL-BASED; HEDGEHOG SIGNALING; HISTONE DEACETYLASES; IN-VITRO; LYSINE RESIDUES; PROTEIN KINASE A; PROTEIN MODIFICATIONS; REPORTER ASSAY; SERINE RESIDUES; SMALL UBIQUITIN-LIKE MODIFIERS; SUMOYLATION; TRANSCRIPTIONAL ACTIVITY;

PHOSPHORYLATION; TRANSCRIPTION FACTORS;

AMINO ACIDS;

CYCLIC AMP DEPENDENT PROTEIN KINASE; HISTONE DEACETYLASE 5; SONIC HEDGEHOG PROTEIN; SUMO PROTEIN; TRANSCRIPTION FACTOR GLI2;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONJUGATION; CONTROLLED STUDY; EMBRYO; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SUMOYLATION; TRANSCRIPTION TERMINATION;

ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENETIC LOCI; HEK293 CELLS; HISTONE DEACETYLASES; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MUTATION; SUMO-1 PROTEIN; SUMOYLATION; TRANSCRIPTION, GENETIC;

ERINACEIDAE;

EID: 84861998949     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.359299     Document Type: Article

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