Dual regeneration of muscle and nerve by intravenous administration of human amniotic fluid-derived mesenchymal stem cells regulated by stromal cell-derived factor-1α in a sciatic nerve injury model: Laboratory investigation

Journal of Neurosurgery

Volumn 116, Issue 6, 2012, Pages 1357-1367

  Yang, Dar Yu ^a   Sheu, Meei Ling ^b   Su, Hong Lin ^b   Cheng, Fu Chou ^c   Chen, Ying Ju ^c   Chen, Chun Jung ^c   Chiu, Wen Ta ^d   Yiin, Jia Jean ^c   Sheehan, Jason ^e   Pan, Hung Chuan ^b,c  

^a CHANG BING SHOW CHWAN MEMORIAL HOSPITAL   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Amniotic fluid derived mesenchymal stem cell; Nerve regeneration; Peripheral nerve; Sciatic nerve crush injury; Stromal cell derived factor 1

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CHEMOKINE RECEPTOR CXCR4; CHOLINERGIC RECEPTOR; CILIARY NEUROTROPHIC FACTOR; DESMIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; PROTEIN S 100; RECOMBINANT PROTEIN; RECOMBINANT STROMAL CELL DERIVED FACTOR 1ALPHA; STROMAL CELL DERIVED FACTOR 1ALPHA; UNCLASSIFIED DRUG;

AMNIOTIC FLUID CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROSCOPY; MUSCLE REGENERATION; MYELINATION; NERVE CRUSH; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCIATIC NERVE INJURY; TREATMENT OUTCOME; WOUND HEALING;

AMNIOTIC FLUID; ANIMALS; CHEMOKINE CXCL12; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MUSCLE, SKELETAL; NERVE CRUSH; NERVE REGENERATION; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CXCR4; SCIATIC NERVE;

EID: 84861997843     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2012.2.JNS111360     Document Type: Article

References (28)

1. Bain JR, Mackinnon SE, Hunter DA: Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat. Plast Reconstr Surg 83:129-138, 1989
2. Cheng FC, Tai MH, Sheu ML, Chen CJ, Yang DY, Su HL, et al: Enhancement of regeneration with glia cell line-derived neurotrophic factor-transduced human amniotic fluid mesenchymal stem cells after sciatic nerve crush injury. Laboratory investigation. J Neurosurg 112:868-879, 2010
3. Clow C, Jasmin BJ: Brain-derived neurotrophic factor regulates satellite cell differentiation and skeltal muscle regeneration. Mol Biol Cell 21:2182-2190, 2010
4. Davis S, Aldrich TH, Ip NY, Stahl N, Scherer S, Farruggella T, et al: Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses. Science 259:1736-1739, 1993
5. Dezawa M, Takahashi I, Esaki M, Takano M, Sawada H: Sciaticnerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells. Eur J Neurosci 14:1771-1776, 2001
6. Ernfors P, Lee KF, Kucera J, Jaenisch R: Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77:503-512, 1994
7. Fischer UM, Harting MT, Jimenez F, Monzon-Posadas WO, Xue H, Savitz SI, et al: Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect. Stem Cells Dev 18:683-692, 2009
8. Gleichmann M, Gillen C, Czardybon M, Bosse F, Greiner-Petter R, Auer J, et al: Cloning and characterization of SDF-1gamma, a novel SDF-1 chemokine transcript with developmentally regulated expression in the nervous system. Eur J Neurosci 12:1857-1866, 2000
9. Helgren ME, Squinto SP, Davis HL, Parry DJ, Boulton TG, Heck CS, et al: Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle. Cell 76:493-504, 1994
10. Ip FC, Cheung J, Ip NY: The expression profiles of neurotrophins and their receptors in rat and chicken tissues during development. Neurosci Lett 301:107-110, 2001
11. Lin KL, Yang DY, Chu IM, Cheng FC, Chen CJ, Ho SP, et al: DuraSeal as a ligature in the anastomosis of rat sciatic nerve gap injury. J Surg Res 161:101-110, 2010
12. Marques MJ, Neto HS: Ciliary neurotrophic factor stimulates in vivo myotube formation in mice. Neurosci Lett 234:43-46, 1997
13. Murakami T, Fujimoto Y, Yasunaga Y, Ishida O, Tanaka N, Ikuta Y, et al: Transplanted neuronal progenitor cells in a peripheral nerve gap promote nerve repair. Brain Res 974:17-24, 2003
14. Nagaya N, Fujii T, Iwase T, Ohgushi H, Itoh T, Uematsu M, et al: Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. Am J Physiol Heart Circ Physiol 287:H2670-H2676, 2004
15. Pan HC, Chen CJ, Cheng FC, Ho SP, Liu MJ, Hwang SM, et al: Combination of G-CSF administration and human amniotic fluid mesenchymal stem cell transplantation promotes peripheral nerve regeneration. Neurochem Res 34:518-527, 2009
16. Pan HC, Cheng FC, Chen CJ, Lai SZ, Lee CW, Yang DY, et al: Post-injury regeneration in rat sciatic nerve facilitated byneurotrophic factors secreted by amniotic fluid mesenchymal stem cells. J Clin Neurosci 14:1089-1098, 2007
17. Pan HC, Chin CS, Yang DY, Ho SP, Chen CJ, Hwang SM, et al: Human amniotic fluid mesenchymal stem cells in combination with hyperbaric oxygen augment peripheral nerve regeneration. Neurochem Res 34:1304-1316, 2009
18. Pan HC, Yang DY, Chiu YT, Lai SZ, Wang YC, Chang MH, et al: Enhanced regeneration in injured sciatic nerve by human amniotic mesenchymal stem cell. J Clin Neurosci 13:570-575, 2006
19. Pan HC, Yang DY, Ou YC, Ho SP, Cheng FC, Chen CJ: Neuroprotective effect of atorvastatin in an experimental model of nerve crush injury. Neurosurgery 67:376-389, 2010
20. Pitts EV, Potluri S, Hess DM, Balice-Gordon RJ: Neurotrophin and Trk-mediated signaling in the neuromuscular system. Int Anesthesiol Clin 44:21-76, 2006
21. Pollock M: Nerve regeneration. Curr Opin Neurol 8:354-358, 1995
22. Rosen JM, Pham HN, Hentz VR: Fascicular tubulization: a comparison of experimental nerve repair techniques in the cat. Ann Plast Surg 22:467-478, 1989
23. Sheard PW, Musaad K, Duxson MJ: Distribution of neurotrophin receptors in the mouse neuromuscular system. Int J Dev Biol 46:569-575, 2002
24. Shen ZL, Lassner F, Becker M, Walter GF, Bader A, Berger A: Viability of cultured nerve grafts: an assessment of proliferation of Schwann cells and fibroblasts. Microsurgery 19: 356-363, 1999
25. Sheu ML, Cheng FC, Su HL, Chen YJ, Chen CJ, Chiang CM, et al: Recruitment by SDF-1 of CD34-positive cells involved in sciatic nerve regeneration. Laboratory investigation. J Neurosurg 116:432-444, 2012
26. Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL, Chang YJ: Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells. Biol Reprod 74:545-551, 2006
27. Wang F, Yasuhara T, Shingo T, Kameda M, Tajiri N, Yuan WJ, et al: Intravenous administration of mesenchymal stem cells exerts therapeutic effects on parkinsonian model of rats: focusing on neuroprotective effects of stromal cell-derived factor-1alpha. BMC Neurosci 11:52, 2010
28. Zhang M, Mal N, Kiedrowski M, Chacko M, Askari AT, Popovic ZB, et al: SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction. FASEB J 21:3197-3207, 2007