The anti-inflammatory effects of the 5-HT 3 receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes

International Immunopharmacology

Volumn 13, Issue 4, 2012, Pages 398-402

  Stratz, Christian ^a   Bhatia, Harsharan S ^b   Akundi, Ravi Shankar ^b   Nührenberg, Thomas ^a   Trenk, Dietmar ^a   Muñoz, Eduardo ^c   Fiebich, Bernd L ^a,b,d  

^a UNIVERSITY HEART CENTER FREIBURG BAD KROZINGEN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF CÓRDOBA   (Spain)

^d VIVACELL BIOTECHNOLOGY GMBH   (Germany)

Author keywords

Cyclooxygenase; Cytokines; Monocytes; Prostaglandin E 2; Serotonin; Tropisetron

Indexed keywords

INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; SEROTONIN 3 RECEPTOR; TROPISETRON; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MONOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPORTER GENE; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELLS, CULTURED; CYTOKINES; GENE EXPRESSION REGULATION; HUMANS; IMMUNIZATION; INDOLES; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RNA PROCESSING, POST-TRANSCRIPTIONAL; SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861991893     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.05.013     Document Type: Article

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