Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines

Journal of Inorganic Biochemistry

Volumn 114, Issue , 2012, Pages 65-74

  Morais, Tânia S ^a   Silva, Tiago J L ^a,b   Marques, Fernanda ^c   Robalo, M Paula ^d,e   Avecilla, Fernando ^f   Madeira, Paulo J Amorim ^a   Mendes, Paulo J G ^b   Santos, Isabel ^c   Garcia, M Helena ^a  

^a UNIVERSITY OF LISBON   (Portugal)

^b UNIVERSITY OF ÉVORA   (Portugal)

^c INSTITUTO TECNOLÓGICO E NUCLEAR   (Portugal)

^d INSTITUTO SUPERIOR DE ENGENHARIA DE LISBOA   (Portugal)

^e INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^f UNIVERSITY OF A CORUÑA   (Spain)

Author keywords

Cyclopentadienyl; Cytotoxicity; DFT calculations; Heteroaromatic ligand; Organometallic; Ruthenium(II)

Indexed keywords

CISPLATIN; RUTHENIUM COMPLEX;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN A2780; CELL STRAIN A2780 CISR; CELL STRAIN HT29; CELL STRAIN MCF 7; CELL STRAIN MDAMB231; CELL STRAIN PC3; CRYSTAL STRUCTURE; CYTOTOXICITY; DENSITY FUNCTIONAL THEORY; DRUG ACTIVITY; DRUG SYNTHESIS; IC 50; X RAY DIFFRACTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; CRYSTALLOGRAPHY, X-RAY; ELECTROCHEMICAL TECHNIQUES; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; ORGANOMETALLIC COMPOUNDS; QUANTUM THEORY; RUTHENIUM; STATIC ELECTRICITY;

EID: 84861986235     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2012.04.014     Document Type: Article

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