Spectral analyses of cardiovascular control in rodents with spinal cord injury

Journal of Neurotrauma

Volumn 29, Issue 8, 2012, Pages 1638-1649

  Inskip, Jessica A ^a,b   Ramer, Leanne M ^b   Ramer, Matt S ^b   Krassioukov, Andrei V ^b,c   Claydon, Victoria E ^a,b  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c GF STRONG REHABILITATION CENTRE   (Canada)

Author keywords

autonomic nervous system; cardiovascular control; spectral analysis; spinal cord injury

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTONOMIC DYSREFLEXIA; BLOOD PRESSURE REGULATION; BLOOD PRESSURE VARIABILITY; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; HEART RATE VARIABILITY; HUMAN; HYPERTENSION; MALE; NONHUMAN; ORTHOSTATIC HYPOTENSION; RAT; SPINAL CORD INJURY; UNIVARIATE ANALYSIS;

ANIMALS; AUTONOMIC DYSREFLEXIA; AUTONOMIC PATHWAYS; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; HEART RATE; HYPOTENSION, ORTHOSTATIC; MALE; RATS; RATS, WISTAR; SPINAL CORD INJURIES;

EID: 84861980460     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2011.2145     Document Type: Article

References (68)

1. Akselrod, S., Gordon, D., Madwed, J.B., Snidman, N.C., Shannon, D.C., and Cohen, R.J. (1985). Hemodynamic regulation: investigation by spectral analysis. Am. J. Physiol 249, H867-H875. (Pubitemid 16207232)
2. Akselrod, S. (1988). Spectral analysis of fluctuations in cardiovascular parameters: a quantitative tool for the investigation of autonomic control. Trends Pharmacol. Sci. 9, 6-9.
3. Alan, N., Ramer, L.M., Inskip, J.A., Golbidi, S., Ramer, M.S., Laher, I., and Krassioukov, A.V. (2010). Recurrent autonomic dysreflexia exacerbates vascular dysfunction after spinal cord injury. Spine. J. 10, 1108-1117.
4. Anderson, K.D. (2004). Targeting recovery: priorities of the spinal cord-injured population. J. Neurotrauma 21, 1371-1383.
5. Bartoli, F., Baselli, G., and Cerutti, S. (1985). AR identification and spectral estimate applied to the R-R interval measurements. Int. J. Biomed. Comput. 16, 201-215. (Pubitemid 15050119)
6. Baselli, G., Cerutti, S., Civardi, S., Liberati, D., Lombardi, F., Malliani, A., and Pagani, M. (1986). Spectral and cross-spectral analysis of heart rate and arterial blood pressure variability signals. Comput. Biomed. Res. 19, 520-534. (Pubitemid 17223074)
7. Bauman, W.A., Raza, M., Spungen, A.M., and Machac, J. (1994). Cardiac stress testing with thallium-201 imaging reveals silent ischemia in individuals with paraplegia. Arch. Phys. Med. Rehabil. 75, 946-950. (Pubitemid 24288454)
8. Cerutti, C., Barres, C., and Paultre, C. (1994). Baroreflex modulation of blood pressure and heart rate variabilities in rats: assessment by spectral analysis. Am. J. Physiol. 266, H1993-H2000.
9. Cerutti, C., Gustin, M.P., Paultre, C.Z., Lo, M., Julien, C., Vincent, M., and Sassard, J. (1991). Autonomic nervous system and cardiovascular variability in rats: a spectral analysis approach. Am. J. Physiol. 261, H1292-H1299.
10. Cerutti, C., Gustin, M.P., Paultre, C.Z., Lo, M., Julien, C., Vincent, M., and Sassard, J. (1992). Role of the autonomic nervous system in blood pressure and heart rate variability in rats: a spectral analysis approach., in: Blood Pressure and Heart Rate Variability. M. Di Rienzo, G. Mancia, G. Parati, A. Pedotti, and A. Zanchetti (eds). IOS Press: Lansdale, PA, pps. 180-191.
11. Cevese, A., Gulli, G., Polati, E., Gottin, L., and Grasso, R. (2001). Baroreflex and oscillation of heart period at 0.1 Hz studied by alpha-blockade and cross-spectral analysis in healthy humans. J. Physiol. 531, 235-244. (Pubitemid 32178040)
12. Claydon, V.E. and Krassioukov, A.V. (2007). Clinical correlates of frequency analyses of cardiovascular control after spinal cord injury. Am. J. Physiol. 294, H668-H678.
13. Claydon, V.E. and Krassioukov, A.V. (2006). Orthostatic hypotension and autonomic pathways after spinal cord injury. J. Neurotrauma 23, 1713-1725. (Pubitemid 46034446)
14. Claydon, V.E., Hol, A.T., Eng, J.J., and Krassioukov, A.V. (2006a). Cardiovascular control and post-exercise hypotension following arm cycling exercise in individuals with spinal cord injury. Arch. Phys. Med. Rehabil. 87, 1106-1114. (Pubitemid 44107855)
15. Claydon, V.E., Elliott, S.L., Sheel, A.W., and Krassioukov, A.V. (2006b). Cardiovascular responses to vibrostimulation for sperm retrieval in men with spinal cord injury. J. Spinal Cord Med. 29, 207-216.
16. Claydon, V.E., Steeves, J.D., and Krassioukov, A. (2006c). Orthostatic hypotension following spinal cord injury: understanding clinical pathophysiology. Spinal Cord 44, 341-351. (Pubitemid 43863344)
17. Cohen, M.A. and Taylor, J.A. (2002). Short-term cardiovascular oscillations in man: measuring and modelling the physiologies. J. Physiol. 542, 669-683. (Pubitemid 34947264)
18. Collins, H.L., Rodenbaugh, D.W., and Dicarlo, S.E. (2006). Spinal cord injury alters cardiac electrophysiology and increases the susceptibility to ventricular arrhythmias. Prog. Brain Res. 152, 275-288. (Pubitemid 41392869)
19. Curt, A. and Dietz, V. (1999). Electrophysiological recordings in patients with spinal cord injury: significance for predicting outcome. Spinal Cord 37, 157-165. (Pubitemid 29149992)
20. Curt, A., Weinhadt, C., and Dietz, V. (1996). Significance of sympathetic skin response in the assessment of autonomic failure in patients with spinal cord injury. J. Auton. Nerv. Sys. 61, 175-180. (Pubitemid 26384342)
21. Ditor, D.S., Kamath, M.V., MacDonald, M.J., Bugaresti, J., McCartney, N., and Hicks, A.L. (2005). Reproducibility of heart rate variability and blood pressure variability in individuals with spinal cord injury. Clin. Auton. Res. 15, 387-393. (Pubitemid 41803755)
22. Drory, Y., Ohry, A., Brooks, M.E., Dolphin, D., and Kellermann, J.J. (1990). Arm crank ergometry in chronic spinal cord injured patients. Arch. Phys. Med. Rehabil. 71, 389-392. (Pubitemid 20157647)
23. Duschek, S., Weisz, N., and Schandry, R. (2003). Reduced cognitive performance and prolonged reaction time accompany moderate hypotension. Clin. Auton. Res. 13, 427-432. (Pubitemid 38117573)
24. Elliott, S. and Krassioukov, A. (2005). Malignant autonomic dysreflexia in spinal cord injured men. Spinal Cord 44, 386-392.
25. Furlan, J.C., Fehlings, M.G., Shannon, P., Norenberg, M.D., and Krassioukov, A.V. (2003). Descending vasomotor pathways in humans: correlation between axonal preservation and cardiovascular dysfunction after spinal cord injury. J. Neurotrauma 20, 1351-1363. (Pubitemid 38018371)
26. Garshick, E., Kelley, A., Cohen, S.A., Garrison, A., Tun, C.G., Gagnon, D., and Brown, R. (2005). A prospective assessment of mortality in chronic spinal cord injury. Spinal Cord 43, 408-416. (Pubitemid 41039541)
27. Grasso, R., Schena, F., Gulli, G., and Cevese, A. (1997). Does low-frequency variability of heart period reflect a specific parasympathetic mechanism? J. Auton. Nerv. Syst. 63, 30-38. (Pubitemid 27119837)
28. Grimm, D.R., De Meersman, R.E., Almenoff, P.L., Spungen, A.M., and Bauman, W.A. (1997). Sympathovagal balance of the heart in subjects with spinal cord injury. Am. J. Physiol. 272, H835-H842.
29. Grimm, D.R., DeMeersman, R.E., Garofano, R.P., Spungen, A.M., and Bauman, W.A. (1995). Effect of provocative maneuvers on heart rate variability in subjects with quadriplegia. Am. J. Physiol. 268, H2239-H2245.
30. Gulli, G., Claydon, V.E., Slessarev, M., Zenebe, G., Gebremedhin, A., Rivera-Ch, M., Appenzeller, O., and Hainsworth, R. (2007). Autonomic regulation during orthostatic stress in highlanders: comparison with sea-level residents. Exp. Physiol. 92, 427-435. (Pubitemid 46376314)
31. Gulli, G., Cooper, V.L., Claydon, V.E., and Hainsworth, R. (2003). Cross-spectral analysis of cardiovascular parameters whilst supine may identify subjects with poor orthostatic tolerance. Clin. Sci. 105, 119-126.
32. Gulli, G., Wight, V.L., Hainsworth, R., and Cevese, A. (2001). Spectral and cross-spectral autoregressive analysis of cardiovascular variables in subjects with different degrees of orthostatic tolerance. Clin. Auton. Res. 11, 19-27. (Pubitemid 33027786)
33. Hainsworth, R. and Claydon, V.E. (2007). Syncope and fainting, in: Autonomic Failure. R. Bannister and C. Mathias (eds). Oxford University Press: New York, pps. 761-781.
34. Hol, A.T., Eng, J.J., Miller, W.C., Sproule, S., and Krassioukov, A.V. (2007). Reliability and validity of the six-minute arm test for the evaluation of cardiovascular fitness in people with spinal cord injury. J. Neurotrauma 88, 489-495. (Pubitemid 46482433)
35. Houtman, S., Oeseburg, B., Hughson, R.L., and Hopman, M.T. (2000). Sympathetic nervous system activity and cardiovascular homeostasis during head-up tilt in patients with spinal cord injuries. Clin. Auton. Res. 10, 207-212. (Pubitemid 32268927)
36. Imai, K., Kadowaki, T., and Aizawa, Y. (2004). Standardized indices of mortality among persons with spinal cord injury: accelerated aging process. Ind. Health. 42, 213-218. (Pubitemid 38543917)
37. Inoue, K., Miyake, S., Kumashiro, M., Ogata, H., Ueta, T., and Akatsu, T. (1991). Power spectral analysis of blood pressure variability in traumatic quadriplegic humans. Am. J. Physiol. 260, H842-H847.
38. Inoue, K., Ogata, H., Hayano, J., Miyake, S., Kamada, T., Kuno, M., and Kumashiro, M. (1995). Assessment of autonomic function in traumatic quadriplegic and paraplegic patients by spectral analysis of heart rate variability. J. Auton. Nerv. Syst. 54, 225-234.
39. Inskip, J., Plunet, W., Ramer, L., Ramsey, J.B., Yung, A., Kozlowski, P., Ramer, M., Krassioukov, A. (2010). Cardiometabolic risk factors in experimental spinal cord injury. J. Neurotrauma 27, 275-285.
40. Inskip, J.A., Ramer, L.M., Ramer, M.S., and Krassioukov, A.V. (2009). Autonomic assessment of animals with spinal cord injury: tools, techniques and translation. Spinal Cord 47, 2-35.
41. Jensen, M.P., Kuehn, C.M., Amtmann, D., and Cardenas, D.D. (2007). Symptom burden in persons with spinal cord injury. Arch. Phys. Med. Rehabil. 88, 638-645. (Pubitemid 46627535)
42. Johnsen, S.J. and Andersen, N. (1978). On power estimation in maximum entropy spectral analysis. Geophysics 43, 681-690. (Pubitemid 8610939)
43. Julien, C., Zhang, Z.Q., and Barres, C. (1995). How sympathetic tone maintains or alters arterial pressure. Fundam. Clin. Pharmacol. 9, 343-349.
44. Kleiger, R.E., Stein, P.K., and Bigger, J.T., Jr. (2005). Heart rate variability: measurement and clinical utility. Ann. Noninvasive. Electrocardiol. 10, 88-101. (Pubitemid 40476672)
45. Kooijman, M., de Hoog, M., Rongen, G.A., van Kuppevelt, H.J., Smits, P., and Hopman, M.T. (2007). Local vasoconstriction in spinal cord-injured and able-bodied individuals. J. Appl. Physiol. 103, 1070-1077. (Pubitemid 47358895)
46. Krassioukov, A. and Claydon, V.E. (2006). The clinical problems in cardiovascular control following spinal cord injury: an overview. Prog. Brain Res. 152, 223-229.
47. Krassioukov, A.V. and Weaver, L.C. (1995). Episodic hypertension due to autonomic dysreflexia in acute and chronic spinal cord-injured rats. Am. J. Physiol. 268, H2077-H2083.
48. Krassioukov, A.V., Johns, D.G., and Schramm, L.P. (2002). Sensitivity of sympathetically correlated spinal interneurons, renal sympathetic nerve activity, and arterial pressure to somatic and visceral stimuli after chronic spinal injury. J. Neurotrauma 19, 1521-1529. (Pubitemid 36026209)
49. Krassioukov, A.V., Karlsson, A.K., Wecht, J.M., Wuermser, L.A., Mathias, C.J., and Marino, R.J. (2007). Assessment of autonomic dysfunction following spinal cord injury: Rationale for additions to International Standards for Neurological Assessment. J. Rehabil. Res. Dev. 44, 103-112. (Pubitemid 46890064)
50. Kuwahara, M., Yayou, K., Ishii, K., Hashimoto, S., Tsubone, H., and Sugano, S. (1994). Power spectral analysis of heart rate variability as a new method for assessing autonomic activity in the rat. J. Electrocardiol. 27, 333-337. (Pubitemid 24322519)
51. Laird, A.S., Carrive, P., and Waite, P.M. (2006). Cardiovascular and temperature changes in spinal cord injured rats at rest and during autonomic dysreflexia. J. Physiol. 577, 539-548. (Pubitemid 44804011)
52. Langager, A.M., Hammerberg, B.E., Rotella, D.L., and Stauss, H.M. (2007). Very low-frequency blood pressure variability depends on voltage-gated L-type Ca2 + channels in conscious rats. Am. J. Physiol. Heart Circ. Physiol. 292, H1321-H1327. (Pubitemid 46377119)
53. Mateus, S.R., Beraldo, P.S., and Horan, T.A. (2007). Maximal static mouth respiratory pressure in spinal cord injured patients: correlation with motor level. Spinal Cord 45, 569-575. (Pubitemid 47206964)
54. Mathias, C.J. (2006). Orthostatic hypotension and paroxysmal hypertension in humans with high spinal cord injury. Prog. Brain Res. 152, 231-243.
55. Mayorov, D.N., Adams, M.A., and Krassioukov, A.V. (2001). Telemetric blood pressure monitoring in conscious rats before and after compression injury of spinal cord. J. Neurotrauma 18, 727-736. (Pubitemid 32708989)
56. Munakata, M., Kameyama, J., Kanazawa, M., Nunokawa, T., Moriai, N., and Yoshinaga, K. (1997). Circadian blood pressure rhythm in patients with higher and lower spinal cord injury: simultaneous evaluation of autonomic nervous activity and physical activity. J. Hypertens. 15, 1745-1749. (Pubitemid 28029675)
57. Munakata, M., Kameyama, J., Nunokawa, T., Ito, N., and Yoshinaga, K. (2001). Altered Mayer wave and baroreflex profiles in high spinal cord injury. Am. J Hypertens. 14, 141-148. (Pubitemid 32171566)
58. Myers, J., Lee, M., and Kiratli, J. (2007). Cardiovascular disease in spinal cord injury: an overview of prevalence, risk, evaluation, and management. Am. J. Phys. Med. Rehabil. 86, 142-152. (Pubitemid 46148688)
59. Omboni, S., Parati, G., Di Rienzo, M., Wieling, W., andMancia, G. (1996). Blood pressure and heart rate variability in autonomic disorders: a critical review. Clin. Auton. Res. 6, 171-182. (Pubitemid 26258131)
60. Parati, G., Saul, J.P., Di Rienzo, M., and Mancia, G. (1995). Spectral analysis of blood pressure and heart rate variability in evaluating cardiovascular regulation. A critical appraisal. Hypertension 25, 1276-1286.
61. Perimuter, L.C. and Greenberg, J.J. (1996). Do you mind standing? Cognitive changes in orthostasis. Exp. Brain Res. 22, 325-341.
62. Ramaekers, D., Beckers, F., Demeulemeester, H., and Aubert, A.E. (2002). Cardiovascular autonomic function in conscious rats: a novel approach to facilitate stationary conditions. Ann. Noninvasive. Electrocardiol. 7, 307-318. (Pubitemid 35373397)
63. Ramer, L.M., Inskip, J.A., Ramer, M.S., Steeves, J.D., and Krassioukov, A.V. (2007). The role of peripheral sympathetic-sensory plasticity in autonomic dysreflexia following spinal cord injury. J. Spinal Cord Med. 30, 451.
64. Ramsey, J.B., Ramer, L.M., Inskip, J.A., Alan, N., Ramer, M.S., and Krassioukov, A.V. (2010). Care of rats with complete high-thoracic spinal cord injury. J. Neurotrauma 27, 1709-1722.
65. Randall, D.C., Baldridge, B.R., Zimmerman, E.E., Carroll, J.J., Speakman, R.O., Brown, D.R., Taylor, R.F., Patwardhan, A., and Burgess, D.E. (2005). Blood pressure power within frequency range approximately 0.4Hz in rat conforms to self-similar scaling following spinal cord transection. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288, R737-R741. (Pubitemid 40250587)
66. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. (1996). Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulation 93, 1043-1065.
67. Vidal, J., Javierre, C., Segura, R., Lizarraga, A., Barbany, J.R., and Perez, A. (2003). Physiological adaptations to exercise in people with spinal cord injury. J. Physiol. Biochem. 59, 11-18. (Pubitemid 36889349)
68. Whiteneck, G.G., Charlifue, S.W., Frankel, H.L., Fraser, M.H., Gardner, B.P., Gerhart, K.A., Krishnan, K.R., Menter, R.R., Nuseibeh, I., Short, D.J., and Silver, J.R. (1992). Mortality, morbidity, and psychosocial outcomes of persons spinal cord injured more than 20 years ago. Paraplegia 30, 617-630. (Pubitemid 23010936)