Etiology of community-acquired pneumonia in a population-based study: Link between etiology and patients characteristics, process-of-care, clinical evolution and outcomes

BMC Infectious Diseases

Volumn 12, Issue , 2012, Pages

  Capelastegui, Alberto ^a   España, Pedro P ^a   Bilbao, Amaia ^b   Gamazo, Julio ^a   Medel, Federico ^c   Salgado, Juan ^c   Gorostiaga, Iñaki ^c   Lopez de Goicoechea, Maria J ^a   Gorordo, Inmaculada ^a   Esteban, Cristobal ^a   Altube, Lander ^a   Quintana, Jose M ^a  

^a HOSPITAL DE GALDAKAO   (Spain)

^b CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^c Family Practice Comarca Interior Bizkaia   (Spain)

Author keywords

Etiology; Pneumonia; Population based study

Indexed keywords

BETA LACTAM; MACROLIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADULT; AGE; AGED; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CHLAMYDOPHILA PNEUMONIAE; CHLAMYDOPHILA PSITTACI; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; COXIELLA BURNETII; DISEASE SEVERITY; FEMALE; GENERAL PRACTITIONER; GERIATRIC PATIENT; HOSPITAL; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; INFLUENZA VIRUS; LEGIONELLA PNEUMOPHILA; MAJOR CLINICAL STUDY; MALE; MORTALITY; MYCOPLASMA PNEUMONIAE; PARAINFLUENZA VIRUS; PATHOGENESIS; PATIENT CARE; POPULATION RESEARCH; PROSPECTIVE STUDY; SPAIN; STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BACTERIA; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PNEUMONIA, BACTERIAL; PROSPECTIVE STUDIES; SPAIN; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84861977316     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-12-134     Document Type: Article

References (34)

1. Woodhead MA, Macfarlane JT, McCraken JS, Rose DH, Finch RG. Prospective study of the aetiology and outcome of pneumonia in the community. Lancet 1987, 1:671-674.
2. Jokinen C, Heiskanen L, Juvonen H, Kallinen S, Karkola K, Korppi M, Kurki S, Ronnberg PR, Seppa A, Soimakallio S. Incidence of community-acquired pneumonia in the population of four municipalities in eastern Finland. Am J Epidemiol 1993, 137:977-988.
3. Almirall J, Bolibar I, Vidal J, Sauca G, Coll P, Niklasson B, Bartolome M, Balanzo X. Epidemiology of community-acquired pneumonia in adults: a population-based study. Eur Respir J 2000, 15:757-763. 10.1034/j.1399-3003.2000.15d21.x, 10780770.
4. Benson V, Marano MA. Current estimates from National Health Interview Survey, 1993. Vital & Health Statistics - Series 10: Data from the National Health Survey. Vital Health Stat 1994, 189:13-15.
5. Macfarlane JT, Colville A, Guion A, Macfarlane RM, Rose DH. Prospective study of aetiology and outcome of adult lower respiratory tract infections in the community. Lancet 1993, 341:511-514. 10.1016/0140-6736(93)90275-L, 8094769.
6. Marrie TJ, Peeling RW, Fine MJ, Singer DE, Coley CM, Kapoor WN. Ambulatory patients with community-acquired pneumonia: the frequency of atypical agents and clinical course. Am J Med 1996, 101:508-515. 10.1016/S0002-9343(96)00255-0, 8948274.
7. Ewig S, Torres A. Severe community-acquired pneumococcal pneumonia- what might be done better. Intensive Care Med 1999, 25:143-145. 10.1007/s001340050807, 10193539.
8. Falguera M, Sacristan O, Nogues A, Ruiz-Gonzalez A, Garcia M, Manonelles A, Rubio-Caballero M. Nonsevere community-acquired pneumonia: correlation between cause and severity or comorbidity. Arch Intern Med 2001, 161:1866-1872. 10.1001/archinte.161.15.1866, 11493128.
9. Jokinen C, Heiskanen L, Juvonen H, Kallinen S, Kleemola M, Koskela M, Leinonen M, Ronnberg PR, Saikku P, Sten M, Tarkiainen A, Tukiainen H, Pyorala K, Makela PH. Microbial etiology of community-acquired pneumonia in the adult population of 4 municipalities in eastern Finland. Clin Infect Dis 2001, 32:1141-1154. 10.1086/319746, 11283803.
10. Instituto Vasco de Estadística. Poblational study 2006. Available at:[ http://www.eustat.es/].
11. Espana PP, Capelastegui A, Quintana JM, Soto A, Gorordo I, Garcia-Urbaneja M, Bilbao A. A prediction rule to identify allocation of inpatient care in community-acquired pneumonia. Eur Respir J 2003, 21:695-701. 10.1183/09031936.03.00057302, 12762359.
12. Lim WS, Van der Eerden MM, Laing R, Boersma WG, Karalus N, Town GI, Lewis SA, Macfarlane JT. Defining community-acquired pneumonia severity presentation to hospital: an international derivation and validation study. Thorax 2003, 58:377-382. 10.1136/thorax.58.5.377, 1746657, 12728155.
13. Alfageme I, Aspa J, Bello S, Blanquer R, Borderias L, Bravo C, de Celis R, de Gracia X, Dorca J, Gallardo J, Gallego M, Menendez R, Molinos L, Paredes C, Rajas O, Rello J, Rodriguez de Castro F, Roig J, Sanchez-Gascon F, Torres A, Zalacain R. Grupo de Estudio de la Neumonia Adquirida en la Comunidad. Area de Tuberculosis e Infecciones Respiratorias (TIR)-SEPAR. Guidelines for the diagnosis and management of community-acquired pneumonia. Spanish Society of Pulmonology and Thoracic Surgery (SEPAR). Arch Bronconeumol 2005, 41:272-289.
14. Mandell LA, Wunderink RG, Anzueto A, Bartlett JG, Campbell GD, Dean NC, Dowell SF, File TM, Musher DM, Niederman MS, Torres A, Whitney CG, . Infectious Diseases Society of America. American Thoracic Society Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia. Clin Infect Dis 2007, 44:S27-S72. 10.1086/511159, 17278083, Infectious Diseases Society of America. American Thoracic Society.
15. Menendez R, Torres A, Zalacain R, Aspa J, Martin Villasclaras JJ, Borderias L, Benitez Moya JM, Ruiz-Manzano J, Rodriguez de Castro F, Blanquer J, Perez D, Puzo C, Sanchez Gascon F, Gallardo J, Alvarez C, Molinos L, . Neumofail Group Risk factors of treatment failure in community acquired pneumonia: implications for disease outcome. Thorax 2004, 59:960-965. 10.1136/thx.2003.017756, 1746855, 15516472, Neumofail Group.
16. Levy MM, Fink M, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003, 31:1250-1256. 10.1097/01.CCM.0000050454.01978.3B, 12682500.
17. España PP, Capelastegui A, Gorordo I, Esteban C, Oribe M, Ortega M, Bilbao A, Quintana JM. Development and validation of a clinical prediction rule for severe community-acquired pneumonia. Am J Respir Crit Care Med 2006, 174:1249-1256. 10.1164/rccm.200602-177OC, 16973986.
18. Ruiz-Gonzalez A, Falguera M, Nogues A, Rubio-Caballero M. Is strectococcus pneumoniae the leading cause of pneumonia of unknown etiology? A microbiologic study of lung aspirates in consecutive patients with community-acquired pneumonia. Am J Med 1999, 106:385-390. 10.1016/S0002-9343(99)00050-9, 10225239.
19. Lim WS, Macfarlane JT, Boswell TC, Harrison TG, Rose D, Leinonen M, Saikku P. Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines. Thorax 2001, 56:296-301. 10.1136/thorax.56.4.296, 1746017, 11254821.
20. Sobradillo V, Zalacain R, Capelastegui A, Uresandi F, Corral J. Antibiotic treatment in pneumonia due to Q fever. Thorax 1992, 47:276-278. 10.1136/thx.47.4.276, 463691, 1585291.
21. Sobradillo V, Ansola P, Baranda F, Corral C. Q fever pneumonia: a review of 164 community-acquired cases in the Basque country. Eur Respir J 1989, 2:263-266.
22. Garcia-Perez AL, Astobiza I, Barandica JF, Atxaerandio R, Hurtado A, Juste RA. Short communication: investigation of Coxiella Burnetti occurrence in dairy sheep flocks by bulk-tank milk analysis and antibody level determination. J Dairy Science 2009, 92:1581-1584.
23. Foy HM, Kenny GE, McMahan R, Mansy AM, Grayston JT. Mycoplasma pneumoniae pneumonia in an urban area: five years of surveillance. JAMA 1970, 214:1666-1672. 10.1001/jama.1970.03180090032006, 5536528.
24. Noah ND. Mycoplasma pneumoniae infection in the United Kindom-1967-1973. Br Med J 1974, 2:544-546. 10.1136/bmj.2.5918.544, 1610892, 4407285.
25. Carratala J, Fernandez-Sabe N, Ortega L, Castellsague X, Roson B, Dorca J, Fernandez-Aguera A, Verdaguer R, Martinez J, Manresa F, Gudiol F. Outpatient care compared with hospitalization for community-acquired pneumonia. A randomized trial in low-risk patients. Ann Intern Med 2005, 142:165-172.
26. Lieberman D, Schlaeffer F, Boldur I, Lieberman D, Horowitz S, Friedman MG, Leiononen M, Horovitz O, Manor E, Porath A. Multiple pathogens in adult patients admitted with community-acquired pneumonia: a one year prospective study of 346 consecutive patients. Thorax 1996, 51:179-184. 10.1136/thx.51.2.179, 473032, 8711652.
27. Gutierrez F, Masia M, Rodriguez JC, Mirete C, Soldan B, Padilla S, Hernandez I, Royo G, Martin-Hidalgo A. Community-acquired pneumonia of mixed etiology: prevalence, clinical Characteristics, and outcome. Eur J Clin Microbiol Infect Dis 2005, 24:377-383. 10.1007/s10096-005-1346-2, 15931452.
28. De Roux A, Ewig S, Garcia E, Marcos MA, Mensa J, Lode H, Torres A. Mixed community-acquired pneumonia in hospitalised patients. Eur Respir J 2006, 27:795-800. 10.1183/09031936.06.00058605, 16585087.
29. Almirall J, Boixeda R, Bolibar I, Bassa J, Sauca G, Vidal J, Serra-Prat M, Balanzo X, . GEMPAC Study Group Differences in the etiology of community-acquired pneumonia according to site of care: a population-based study. Respir Med 2007, 101:2168-2175. 10.1016/j.rmed.2007.05.007, 17629472, GEMPAC Study Group.
30. Porath A, Schlaeffer F, Lieberman D. The epidemiology of community-acquired pneumonia among hospitalized patients. J Infect 1993, 34:41-48.
31. Luna CM, Famiglietti A, Absi R, Videla AJ, Nogueira FJ, Fuenzalida AD, Gene RJ. Community-acquired pneumonia. Etiology, epidemiology, and outcome at a teaching hospital in Argentina. Chest 2000, 118:1344-1354. 10.1378/chest.118.5.1344, 11083685.
32. Arnold FW, Summersgill JT, LaJoie AS, Peyrani P, Marrie TJ, Rossi P, Blasi F, Fernandez P, File TM, Rello J, Menendez R, Marzoratti L, Luna CM, Ramirez JA, . Community-Acquired Pneumonia Organization (CAPO) Investigators A worldwide perspective of atypical pathogens in community-acquired pneumonia. Am J Respir Crit Care Med 2007, 175:1086-1093. 10.1164/rccm.200603-350OC, 17332485, Community-Acquired Pneumonia Organization (CAPO) Investigators.
33. Mills GD, Oehley MR, Arrol B. Effectiveness of B lactam antibiotics compared with antibiotics active against atypical pathogens in non-severe community acquired pneumonia: meta-analysis. BMJ 2005, 330:456-462. 10.1136/bmj.38334.591586.82, 549658, 15684024.
34. Fantin B, Aubert JP, Unger P, Lecoeur H, Carbon C. Clinical evaluation of the management of community-acquired pneumonia by general practitioners in France. Chest 2001, 120:185-192. 10.1378/chest.120.1.185, 11451836.