Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure

Journal of Physiology

Volumn 589, Issue 6, 2011, Pages 1367-1382

  Briston, Sarah J ^a   Caldwell, Jessica L ^a   Horn, Margaux A ^a   Clarke, Jessica D ^a   Richards, Mark A ^a   Greensmith, David J ^a   Graham, Helen K ^a   Hall, Mark C S ^b   Eisner, David A ^a   Dibb, Katharine M ^a   Trafford, Andrew W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b LIVERPOOL HEART AND CHEST HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CALCIUM CHANNEL L TYPE; CALCIUM ION; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; EXCITATION CONTRACTION COUPLING; FEMALE; HEART FAILURE; HEART MUSCLE CELL; HEART PACING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOPLASMIC RETICULUM; SHEEP;

ANIMALS; DISEASE MODELS, ANIMAL; EXCITATION CONTRACTION COUPLING; FEMALE; HEART FAILURE; MYOCARDIAL CONTRACTION; RECEPTORS, ADRENERGIC, BETA; SHEEP; TACHYCARDIA, VENTRICULAR;

EID: 79952611078     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.203984     Document Type: Article

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