A feedback control model for cortisol secretion

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Volumn , Issue , 2011, Pages 716-719

  Faghih, Rose T ^a   Savla, Ketan ^a   Dahleh, Munther A ^a   Brown, Emery N ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOCORTICOTROPIC HORMONES; COMPREHENSIVE MODEL; CORTICOTROPIN-RELEASING HORMONE; CORTISOL SECRETION; FEED-BACK LOOP; FEEDBACK CONTROL MODELS; KEY FEATURE; NEURAL FIRING; TIME VARYING;

MODELS; PHYSIOLOGY;

MATHEMATICAL MODELS;

CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; HYDROCORTISONE;

ACTION POTENTIAL; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BLOOD; COMPUTER SIMULATION; FEEDBACK SYSTEM; HUMAN; HYPOTHALAMUS; METABOLISM; NERVE CELL; PHYSIOLOGY; SECRETION (PROCESS); SECRETION;

ACTION POTENTIALS; ADRENOCORTICOTROPIC HORMONE; ANIMALS; COMPUTER SIMULATION; CORTICOTROPIN-RELEASING HORMONE; FEEDBACK, PHYSIOLOGICAL; HUMANS; HYDROCORTISONE; HYPOTHALAMUS; MODELS, NEUROLOGICAL; NEURONS;

EID: 84861931909     PISSN: 1557170X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/IEMBS.2011.6090162     Document Type: Conference Paper

References (14)

1. Brown E.N., Meehan P.M., Dempster A.P. "A stochastic differential equation model of diurnal cortisol patterns." American Journal of Physiology Endocrinology and Metabolism, Vol. 280:E450E461, 2001.
2. Dallman M.F. and E.F. Yates. "Dynamic Asymmetries in the Corticosteroid Feedback Path and Distribution-Metabolism-Binding Elements of the Adrenocortical System." Ann. NY Acad. Sci., vol. 156: 696-721, 1969.
3. Faghih R.T., Savla K, Dahleh M.A., Brown E.N. "The FitzHugh-Nagumo Model: Firing Modes with Time Varying Parameters and Parameter Estimation," Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Buenos Aires, Argentina, p. 4116-4119, Summer 2010.
4. Faghih R.T., 2010. "The FitzHugh-Nagumo model dynamics with an application to the hypothalamic pituitary adrenal axis." Masters Thesis, MIT, p.70.
5. Gupta Sh, Aslakson E, Gurbaxani B.M., Vernon S.D. "Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability." Theoretical Biology and Medical Modelling, 4:8, 2007.
6. Korszun A, Young E.A., Singer K, Carlson N.E., Brown M.B., Crofford L. "Basal Circadian Cortisol Secretion in Women with Temporomandibular Disorders." Journal of Dental Research, Vol. 81: 279-283, 2002.
7. Kyrylov V, Severyanova L.A., Vieira A."Modeling Robust Oscillatory Behavior of the Hypothalamic-Pituitary-Adrenal Axis." IEEE Transaction on Biomedical Engineering, Vol. 52, No. 12:1977-1983, 2005.
8. LeBeau A.P., Robson A.B., McKinnon A.E., Donald R.A., Sneyd J. "Generation of Action Potentials in a Mathematical Model of Corticotrophs." Biophysical Journal, Vol. 73: 1263-1275, 1997.
9. LeBeau A.P., Robson A.B., McKinnon A.E., Sneyd J."Analysis of a Reduced Model of Corticotrophs Action Potentials." J. Theor. Biol., Vol. 192: 319-339, 1998.
10. Savic D and S Jelic. "A mathematical model of the hypothalamopituitary-adrenocortical system and its stability analysis." Chaos Solutions and Fractals, Vol. 26:427-436, 2005.
11. Shorten P.R., Robson A.B., McKinnon AE, Wall DJN, "CRH-induced Electrical Activity and Calcium Signaling in Pituitary Corticotrophs." J. Theor. Biol., Vol. 206: 395-405, 2000.
12. Churilov A, Medvedev A, Shepeljavyi A. "Mathematical model of non-basal testosterone regulation in the male by pulse modulated feedback." Automatica Vol.45:78-85, 2009.
13. Leng G and D Brown. "The Origins and Significance of Pulsatility in Hormone Secretion from the Pituitary." Journal of Neuroenocrinology, Vol. 9:493-513,1997.
14. Terasawa E. "Luteinizing hormone-releasing hormone (LHRH) neurons: mechanism of pulsatile LHRH release." Vitamins and Hormones, Vol. 63: 91-129, 2001.